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HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane]
Stable Identifier
R-HSA-1236793
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
phagocytic vesicle membrane
Synonyms
HLAE_HUMAN, HLA-E
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
ER-Phagosome pathway (Homo sapiens)
Export of peptide loaded MHC class I complex to PM (Homo sapiens)
Ag peptide bound class I MHC [phagocytic vesicle membrane] (Homo sapiens)
Class I MHC HC:B2M [phagocytic vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [phagocytic vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane] (Homo sapiens)
Fusion of ERC and phagosome (Homo sapiens)
Class I MHC HC:B2M:Erp57 [phagocytic vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [phagocytic vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane] (Homo sapiens)
Peptide loading on MHC class I in phagosome (Homo sapiens)
Ag peptide bound class I MHC [phagocytic vesicle membrane] (Homo sapiens)
Class I MHC HC:B2M [phagocytic vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [phagocytic vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane] (Homo sapiens)
Class I MHC HC:B2M:Erp57 [phagocytic vesicle membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [phagocytic vesicle membrane] (Homo sapiens)
HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P13747 HLA-E
Gene Names
HLA-E, HLA-6.2, HLAE
Chain
signal peptide:1-21, chain:22-358, chain:22-
Reference Genes
BioGPS Gene:3133 HLA-E
COSMIC (genes):HLA-E HLA-E
CTD Gene:3133 HLA-E
dbSNP Gene:3133 HLA-E
ENSEMBL:ENSG00000204592 HLA-E
ENSEMBL_homo_sapiens_GENE:ENSG00000204592.9 HLA-E
ENSEMBL_homo_sapiens_GENE:ENSG00000206493.7 HLA-E
ENSEMBL_homo_sapiens_GENE:ENSG00000225201.6 HLA-E
ENSEMBL_homo_sapiens_GENE:ENSG00000229252.6 HLA-E
ENSEMBL_homo_sapiens_GENE:ENSG00000230254.7 HLA-E
ENSEMBL_homo_sapiens_GENE:ENSG00000233904.6 HLA-E
ENSEMBL_homo_sapiens_GENE:ENSG00000236632.5 HLA-E
HGNC:4962 HLA-E
KEGG Gene (Homo sapiens):3133 HLA-E
Monarch:3133 HLA-E
NCBI Gene:3133 HLA-E
OMIM:143010 HLA-E
UCSC:P13747 HLA-E
Reference Transcript
RefSeq:NM_005516.5 HLA-E
Other Identifiers
11723195_x_at
11744829_s_at
11748332_x_at
11751618_x_at
11753404_x_at
11758879_s_at
17006261
17027443
17030288
17032993
17035115
17037774
17040488
200904_PM_at
200904_at
200905_PM_x_at
200905_x_at
217456_3p_x_at
217456_PM_x_at
217456_x_at
2900990
2901162
2901216
2901621
2901622
2901624
2901625
2901627
2901628
2901629
2901630
2901631
2901632
2901633
2901634
2901637
2901639
2901641
2901642
2901643
2901644
2901645
2901646
2901647
2901648
2948945
2948946
3133
32321_at
8117890
8177788
8179103
A_23_P30848
A_24_P326082
A_32_P460973
GE61370
GE81522
GO:0000139
GO:0001815
GO:0001916
GO:0002250
GO:0002376
GO:0002474
GO:0002476
GO:0002477
GO:0002486
GO:0002519
GO:0002639
GO:0002715
GO:0002717
GO:0002729
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005768
GO:0005783
GO:0005794
GO:0005886
GO:0006954
GO:0006955
GO:0007155
GO:0009897
GO:0009986
GO:0012507
GO:0016020
GO:0019731
GO:0019882
GO:0030670
GO:0030881
GO:0031410
GO:0031901
GO:0032398
GO:0032736
GO:0032753
GO:0032759
GO:0032760
GO:0032815
GO:0032816
GO:0032819
GO:0036037
GO:0042130
GO:0042270
GO:0042288
GO:0042605
GO:0042608
GO:0042612
GO:0043226
GO:0045087
GO:0045953
GO:0045954
GO:0046703
GO:0048856
GO:0050830
GO:0055038
GO:0070062
GO:0098542
GO:0098553
GO:2000566
GO:2001187
HMNXSV003053079
Hs.181392.0.A2_3p_at
Hs.181392.1.A1_3p_a_at
Hs.181392.1.A1_3p_x_at
ILMN_1765258
PH_hs_0038975
TC06000338.hg
TC6_cox_hap2000036.hg
TC6_dbb_hap3000029.hg
TC6_mann_hap4000031.hg
TC6_mcf_hap5000023.hg
TC6_qbl_hap6000029.hg
TC6_ssto_hap7000029.hg
X56841_at
Participates
as a member of
Class I MHC heavy chain (MHC HC) [phagocytic vesicle membrane] (Homo sapiens)
Other forms of this molecule
HLA class I histocompatibility antigen, E alpha chain precursor [early endosome membrane]
HLA class I histocompatibility antigen, E alpha chain precursor [recycling endosome membrane]
HLA class I histocompatibility antigen, E alpha chain precursor [Golgi membrane]
HLA class I histocompatibility antigen, E alpha chain precursor [ER to Golgi transport vesicle membrane]
HLA class I histocompatibility antigen, E alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane]
HLA class I histocompatibility antigen, E alpha chain precursor [plasma membrane]
Inferred To
Homologues of HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane]
(Danio rerio)
Homologues of HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane]
(Gallus gallus)
dZ63M10.1 [phagocytic vesicle membrane]
(Danio rerio)
hlazel [phagocytic vesicle membrane]
(Danio rerio)
UBA*01 [phagocytic vesicle membrane]
(Danio rerio)
si:ch211-287j19.6 [phagocytic vesicle membrane]
(Danio rerio)
BF1 [phagocytic vesicle membrane]
(Gallus gallus)
CH73-211L2.2 [phagocytic vesicle membrane]
(Danio rerio)
HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane]
(Danio rerio)
HLA class I histocompatibility antigen, E alpha chain precursor [phagocytic vesicle membrane]
(Gallus gallus)
Cross References
RefSeq
NP_005507.3
OpenTargets
ENSG00000204592
GeneCards
P13747
HPA
ENSG00000204592-HLA-E
Ensembl
ENSG00000233904
,
ENSP00000390707
,
ENST00000383597
,
ENST00000415289
,
ENSG00000225201
,
ENSG00000236632
,
ENSP00000409910
,
ENST00000376630
,
ENSP00000400458
,
ENST00000425603
,
ENST00000444683
,
ENST00000427936
,
ENSG00000206493
,
ENSG00000204592
,
ENST00000415649
,
ENSP00000365817
,
ENSP00000402694
,
ENSP00000373091
,
ENSP00000397420
,
ENSG00000230254
,
ENSG00000229252
PRO
P13747
Pharos - Targets
P13747
PDB
6ZKW
,
6GHN
,
1KPR
,
5W1V
,
6ZKZ
,
7NDT
,
3BZF
,
7NDQ
,
6GH1
,
3CII
,
6ZKY
,
6ZKX
,
6GGM
,
3BZE
,
1KTL
,
2ESV
,
7BH8
,
7NDU
,
6GH4
,
3AM8
,
6GL1
,
1MHE
,
5W1W
,
7P49
,
3CDG
,
7P4B
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