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LNPEP [early endosome lumen]
Stable Identifier
R-HSA-1236834
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
early endosome lumen
Synonyms
IRAP, LAP, Leucyl-cystinyl aminopeptidase, LNPEP, LCAP_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
Endosomal/Vacuolar pathway (Homo sapiens)
Trimming of peptides by IRAP in endocytic vesicles (Homo sapiens)
IRAP in complex with MHC class I [early endosome membrane] (Homo sapiens)
LNPEP [early endosome lumen] (Homo sapiens)
LNPEP [early endosome lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UIQ6 LNPEP
Gene Names
LNPEP, OTASE
Chain
chain:1-1025, chain:155-1025
Reference Genes
BioGPS Gene:4012 LNPEP
COSMIC (genes):LNPEP LNPEP
CTD Gene:4012 LNPEP
dbSNP Gene:4012 LNPEP
ENSEMBL:ENSG00000113441 LNPEP
HGNC:6656 LNPEP
KEGG Gene (Homo sapiens):4012 LNPEP
Monarch:4012 LNPEP
NCBI Gene:4012 LNPEP
OMIM:151300 LNPEP
UCSC:Q9UIQ6 LNPEP
Reference Transcript
RefSeq:NM_005575.2 LNPEP
RefSeq:NM_175920.3 LNPEP
Other Identifiers
0004850377
11729353_a_at
16987565
207904_s_at
225176_at
231866_3p_at
231866_at
243532_at
2821425
2821429
2821430
2821432
2821434
2821436
2821437
2821440
2821441
2821444
2821446
2821447
2821449
2821451
2821452
2821453
2821456
2821459
2821463
2821464
2821466
2821467
2821468
2821469
2821470
2821471
2821472
2821473
2821474
2821475
2821476
2821477
2821478
2821480
2821482
35421_at
4012
43642
44720_at
4P8Q
4PJ6
4Z7I
5C97
5JHQ
5MJ6
60491_at
69509_f_at
69511_r_at
73530_at
76557_at
79589_g_at
8107066
82675_f_at
A_14_P108542
A_14_P118676
A_23_P144677
A_23_P156061
A_24_P132019
A_32_P69475
AAB66672
AAB66673
AB208883
AJ131023
AJ131025
AJ131026
AJ131027
AJ131028
AJ131029
AJ131030
AJ131031
AJ131032
AJ131033
AJ131034
AJ131035
AJ131036
AJ131037
AJ131038
AJ131039
BAA09436
BAD92120
CAB61646
CAB94753
CCDS4087
CCDS43346
D50810
D50810_at
ENSG00000113441
ENSP00000231368
ENSP00000379117
ENST00000231368
ENST00000231368.9
ENST00000395770
ENST00000395770.3
EntrezGene:4012
EntrezGene:LNPEP
g5031880_3p_a_at
GE55213
GE885073
GO:0000003
GO:0000209
GO:0002376
GO:0002480
GO:0003674
GO:0004177
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005623
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005829
GO:0005886
GO:0005887
GO:0006464
GO:0006508
GO:0007165
GO:0007267
GO:0007565
GO:0008150
GO:0008233
GO:0008237
GO:0008270
GO:0009056
GO:0016020
GO:0016021
GO:0016787
GO:0030163
GO:0030659
GO:0031410
GO:0031905
GO:0034641
GO:0042277
GO:0042592
GO:0043167
GO:0043171
GO:0043226
GO:0046872
GO:0048471
GO:0060395
GO:0070006
GO:0120163
HGNC:6656
HPA043642
Hs.107882.1.A1_3p_s_at
Hs.116278.0.S1_3p_at
Hs.116278.0.S1_3p_x_at
Hs.123337.0.A1_3p_at
ILMN_1720934
ILMN_1758661
ILMN_1814737
ILMN_1875342
IPR001930
IPR014782
IPR024571
IPR034016
IPR034017
IPR042097
LNPEP
LNPEP-201
LNPEP-202
MIM:151300
NM_005575
NM_175920
NP_005566
NP_787116
PF01433
PF11838
PF17900
PH_hs_0006922
PH_hs_0025695
PR00756
TC05000472.hg
U62768
U62769
UPI000013C94B
UPI00004EC287
XM_024446045
XP_024301813
Participant Of
hasComponent
IRAP in complex with MHC class I [early endosome membrane]
Other forms of this molecule
LNPEP [cytoplasmic vesicle membrane]
LNPEP [cytosol]
Inferred To
LNPEP [early endosome lumen] (Bos taurus)
LNPEP [early endosome lumen] (Danio rerio)
LNPEP [early endosome lumen] (Gallus gallus)
LNPEP [early endosome lumen] (Mus musculus)
LNPEP [early endosome lumen] (Rattus norvegicus)
LNPEP [early endosome lumen] (Sus scrofa)
LNPEP [early endosome lumen] (Xenopus tropicalis)
Cross References
RefSeq
NP_787116.2
,
NP_005566.2
ZINC - Metabolites
LCAP_HUMAN
OpenTargets
ENSG00000113441
IntEnz
3.4.11.3
ZINC - Substances
LCAP_HUMAN
GeneCards
Q9UIQ6
ZINC - Biogenic
LCAP_HUMAN
ZINC target
Q9UIQ6
PRO
Q9UIQ6
ZINC - Predictions - Purchasable
LCAP_HUMAN
HMDB Protein
HMDBP02475
PDB
5JHQ
,
5C97
,
4PJ6
,
4Z7I
,
4P8Q
,
5MJ6
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27824 CANX
2
CANX [integral component of lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.527
2
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