Reactome | ZNF420 [nucleoplasm]

ZNF420 [nucleoplasm]

Stable Identifier

R-HSA-1247509

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Zinc finger protein 420, ZN420_HUMAN, Apak, ATM and p53-associated KZNF protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8TAQ5 ZNF420

Gene Names

ZNF420

Chain

chain:1-688

Reference Genes

BioGPS Gene:147923 ZNF420

COSMIC (genes):ZNF420 ZNF420

CTD Gene:147923 ZNF420

dbSNP Gene:147923 ZNF420

ENSEMBL:ENSG00000197050 ZNF420

ENSEMBL_homo_sapiens_GENE:ENSG00000197050.11 ZNF420

HGNC:20649 ZNF420

KEGG Gene (Homo sapiens):147923 ZNF420

Monarch:147923 ZNF420

NCBI Gene:147923 ZNF420

UCSC:Q8TAQ5 ZNF420

Reference Transcript

Other Identifiers

11744188_at

147923

16861500

238937_PM_at

238937_at

242761_PM_s_at

242761_s_at

3831699

3831703

3831704

3831705

3831707

3831708

3831709

3831710

3831711

3831712

3831713

3831714

3831715

3831716

3831717

3831718

3831719

3831720

3831721

3831722

3831723

3831724

3871911

64224_at

76767_at

8028219

A_14_P105591

A_23_P380951

A_33_P3395389

A_33_P3395396

GE477890

GO:0000978

GO:0000981

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0006351

GO:0006355

GO:0006357

GO:0043226

GO:0046872

GO:0140110

HMNXSV003005573

HMNXSV003006014

Hs.133437.0.A1_3p_at

Hs.31511.0.A1_3p_at

ILMN_1720431

PH_hs_0008035

TC19000511.hg

Participates

as a candidate of

KRAB-ZNF [nucleoplasm] (Homo sapiens)

as a component of

ZNF420:TP53AIP1 Gene [nucleoplasm] (Homo sapiens)

as an input of

Other forms of this molecule

p-S68-ZNF420 [nucleoplasm]

Inferred To

Phs [nucleoplasm] (Drosophila melanogaster)

ZNF383 [nucleoplasm] (Bos taurus)

Dmel\CG5245 [nucleoplasm] (Drosophila melanogaster)

Zfp420 [nucleoplasm] (Mus musculus)

Zfp420 [nucleoplasm] (Rattus norvegicus)

ZNF529 [nucleoplasm] (Bos taurus)

Homologues of ZNF420 [nucleoplasm] (Bos taurus)

Homologues of ZNF420 [nucleoplasm] (Drosophila melanogaster)

Homologues of ZNF420 [nucleoplasm] (Gallus gallus)

LOC100336984 [nucleoplasm] (Bos taurus)

LOC100682968 [nucleoplasm] (Canis familiaris)

ZNF420 [nucleoplasm] (Bos taurus)

ZNF420 [nucleoplasm] (Drosophila melanogaster)

ZNF420 [nucleoplasm] (Gallus gallus)

ZNF420 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

XP_011524805.1, NP_653290.2, XP_011524806.1, NP_001316451.1

OpenTargets

ENSG00000197050

GeneCards

Q8TAQ5

HPA

ENSG00000197050-ZNF420

Ensembl

ENSG00000197050, ENSP00000306102, ENST00000304239, ENST00000337995, ENSP00000338770

PRO

Q8TAQ5

Pharos - Targets

Q8TAQ5

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N726 CDKN2A	12	p14ARF [nucleoplasm] (R-HSA-1629813) p14ARF [cytosol] (R-HSA-9645669) p14ARF [mitochondrial matrix] (R-HSA-9645695) p14ARF R98L;R99S [cytosol] (R-HSA-9645730) p14ARF R82C [cytosol] (R-HSA-9645750) p14ARF R90H [cytosol] (R-HSA-9645755) p14ARF R88Q [cytosol] (R-HSA-9645754) p14ARF R87C [cytosol] (R-HSA-9645759) p14ARF R81G [cytosol] (R-HSA-9645741) p14ARF R98Q [cytosol] (R-HSA-9645757) p14ARF R99C [cytosol] (R-HSA-9645756) p14ARF V22Pfs*46 [cytosol] (R-HSA-9646285)	0.644	8
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.591	4
UniProt:Q9NX04 AIRIM			0.556	3
UniProt:Q96LK0 CEP19			0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:P36508 ZNF76			0.556	3
UniProt:Q9NQT4 EXOSC5	2	EXOSC5 [cytosol] (R-HSA-429889) EXOSC5 [nucleoplasm] (R-HSA-6791550)	0.556	3
UniProt:P16104 H2AFX	7	Me2sR4-H2AFX [nucleoplasm] (R-HSA-5218317) H2AFX [nucleoplasm] (R-HSA-56151) p-Y143-H2AFX [nucleoplasm] (R-HSA-5683942) p-S140,Y143-H2AFX [nucleoplasm] (R-HSA-5683953) p-S140-H2AFX [nucleoplasm] (R-HSA-75170) K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm] (R-HSA-5682847) H2AFX [extracellular region] (R-HSA-977583)	0.527	2
UniProt:Q9H4B6 SAV1	2	SAV1 [cytosol] (R-HSA-2028283) p-SAV1 [cytosol] (R-HSA-2028276)	0.527	2
UniProt:Q9BWF3 RBM4	1	RBM4 [cytosol] (R-HSA-8878898)	0.527	2
UniProt:Q13188 STK3	4	p-T180-STK3(1-322) [cytosol] (R-HSA-2028696) STK3(323-491) [cytosol] (R-HSA-2028684) STK3(1-491) [cytosol] (R-HSA-2028280) p-T180-STK3(1-491) [cytosol] (R-HSA-2028274)	0.527	2

Cite Us!