CysGly translocates from extracellular region to cytosol

Stable Identifier
R-HSA-1247939
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The hydrolysis product of glutathione, cysteinylglycine (CysGly) is transported back into the cell to replenish the precursor resevoir for the resynthesis of glutathione. The exact mechanism of uptake is unknown (Griffith et al. 1978).
Literature References
PubMed ID Title Journal Year
31622 Evidence that the gamma-glutamyl cycle functions in vivo using intracellular glutathione: effects of amino acids and selective inhibition of enzymes

Bridges, RJ, Meister, A, Griffith, OW

Proc Natl Acad Sci U S A 1978
Participants
Participates
Authored
Reviewed
Created
Cite Us!