Reactome | NCOR1 [cytosol]

NCOR1 [cytosol]

Stable Identifier

R-HSA-1253310

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Nuclear receptor corepressor 1, NCOR1_HUMAN

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75376 NCOR1

Gene Names

NCOR1, KIAA1047

Chain

chain:1-2440

Reference Genes

BioGPS Gene:9611 NCOR1

COSMIC (genes):NCOR1 NCOR1

CTD Gene:9611 NCOR1

dbSNP Gene:9611 NCOR1

ENSEMBL:ENSG00000141027 NCOR1

HGNC:7672 NCOR1

KEGG:hsa:9611 NCOR1

Monarch:9611 NCOR1

NCBI Gene:9611 NCOR1

OMIM:600849 NCOR1

UCSC:O75376 NCOR1

Reference Transcript

Participates

as a component of

TAB2:NCOR1 [cytosol] (Homo sapiens)

Other forms of this molecule

NCOR1 [nucleoplasm]

Cross References

RefSeq

NP_001177367.1, NP_001177369.1, NP_006302.2, XP_011522388.1

OpenTargets

ENSG00000141027

ENSEMBL

ENSP00000379189, ENSG00000141027, ENST00000395851, ENSP00000268712, ENST00000268712, ENSP00000379192, ENST00000395848

HPA

ENSG00000141027-NCOR1

GeneCards

NCOR1

PRO

O75376

Pharos - Targets

O75376

GlyGen

O75376

PDB

8D8I, 4MDD, 3H52, 6Y17, 6XZZ, 8DKV, 8DKN, 6XXS, 6ONI, 8AS9, 8FHE, 4WVD, 6WMQ, 2EQR, 6WMS, 3KMZ, 8FKD, 6XYX, 8FKC, 8FKF, 3N00, 6ZBU, 8FKE, 8FHG, 8FKG

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15379 HDAC3	2	HDAC3 [nucleoplasm] (R-HSA-442464) Unfolded HDAC3 [cytosol] (R-HSA-6813777)	0.802	6
UniProt:P10276 RARA	3	RARA [nucleoplasm] (R-HSA-446164) polySUMO2-K166,K171,K399-RARA [nucleoplasm] (R-HSA-4341042) SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm] (R-HSA-5334830)	0.802	6
UniProt:Q06455 MTG8			0.72	5
UniProt:P12755 SKI	1	SKI [nucleoplasm] (R-HSA-173473)	0.669	4
UniProt:Q07869 PPARA	2	PPARA [nucleoplasm] (R-HSA-400186) monoSUMO1-K185-PPARA [nucleoplasm] (R-HSA-4341099)	0.658	3
UniProt:Q13133 NR1H3	1	NR1H3 [nucleoplasm] (R-HSA-8854957)	0.642	3
UniProt:P20393 NR1D1	1	NR1D1 [nucleoplasm] (R-HSA-375499)	0.602	3
UniProt:P37231 PPARG	2	PPARG [nucleoplasm] (R-HSA-446172) monoSUMO1-K107,K395-PPARG [nucleoplasm] (R-HSA-4717444)	0.571	2
UniProt:P10275 AR	4	AR [nucleoplasm] (R-HSA-446174) AR [cytosol] (R-HSA-5618082) monoSUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) PolyUb-AR [nucleoplasm] (R-HSA-6782984)	0.569	4
UniProt:P61764 STXBP1	2	STXBP1 [cytosol] (R-HSA-6794256) STXBP1 [plasma membrane] (R-HSA-2980862)	0.556	3
UniProt:P62937 PPIA	5	PPIA [cytosol] (R-HSA-173123) PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [extracellular region] (R-HSA-173646) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [extracellular exosome] (R-HSA-6801538)	0.556	3
UniProt:Q8IUQ4-2 SIAH1			0.556	3
UniProt:Q9UJC3 HOOK1			0.556	3
IntAct:EBI-25907740 CCSB			0.556	3
UniProt:I6L9F6 I6L9F6			0.556	3
UniProt:Q99719 SEPT5			0.556	3
UniProt:Q13263 TRIM28	3	TRIM28 [nucleoplasm] (R-HSA-974998) SUMO2-K554,K575,K676,K750,K779,K804-TRIM28 [nucleoplasm] (R-HSA-9842867) SUMO1-K554,575,676,750,779,804-TRIM28 [nucleoplasm] (R-HSA-3782600)	0.556	4
UniProt:Q9BUG6 ZSA5A			0.527	2
UniProt:Q13227 GPS2	1	GPS2 [nucleoplasm] (R-HSA-351642)	0.527	3
UniProt:Q5SZD1 CF141			0.527	2
UniProt:P56524 HDAC4	3	HDAC4 [nucleoplasm] (R-HSA-351581) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029)	0.527	2
UniProt:Q9BQ87 TBL1Y			0.527	4
UniProt:P55055 NR1H2	3	NR1H2 [nucleoplasm] (R-HSA-375500) polySUMO2,3-K409,K447-NR1H2 [nucleoplasm] (R-HSA-4720435) NR1H2 [cytosol] (R-HSA-9619753)	0.525	6
UniProt:Q92922 SMARCC1	1	SMARCC1 [nucleoplasm] (R-HSA-389257)	0.524	3
UniProt:Q12824 SMARCB1	1	SMARCB1 [nucleoplasm] (R-HSA-389261)	0.524	3
UniProt:P51532 SMARCA4	1	SMARCA4 [nucleoplasm] (R-HSA-201686)	0.524	2
UniProt:Q8TAQ2 SMARCC2	1	SMARCC2 [nucleoplasm] (R-HSA-389263)	0.524	3
UniProt:P06429 VE7			0.488	2
UniProt:P48431 SOX2	1	SOX2 [nucleoplasm] (R-HSA-452271)	0.483	2

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