Reactome | WWOX [cytosol]

WWOX [cytosol]

Stable Identifier

R-HSA-1253335

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

WW domain-containing oxidoreductase, FOR, WOX1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NZC7 WWOX

Gene Names

WWOX, FOR, SDR41C1, WOX1

Chain

chain:1-414

Reference Genes

BioGPS Gene:51741 WWOX

COSMIC (genes):WWOX WWOX

CTD Gene:51741 WWOX

dbSNP Gene:51741 WWOX

ENSEMBL:ENSG00000186153 WWOX

HGNC:12799 WWOX

KEGG Gene (Homo sapiens):51741 WWOX

Monarch:51741 WWOX

NCBI Gene:51741 WWOX

OMIM:605131 WWOX

UCSC:Q9NZC7 WWOX

Reference Transcript

Other Identifiers

0000610400

0003780390

0005910377

0006760575

11721287_a_at

11721288_a_at

11726214_x_at

11730156_a_at

11749046_a_at

16821193

210695_s_at

219077_s_at

221147_x_at

223747_x_at

223868_s_at

3669651

3669652

3669653

3669654

3669657

3669658

3669660

3669674

3669675

3669697

3669710

3669722

3669724

3669786

3669808

3669849

3669850

3669851

3669852

3669853

3670159

39995_s_at

51741

57272_at

77289_at

7997352

89102_i_at

89104_r_at

A_14_P103995

A_14_P129523

A_23_P206413

A_23_P71972

A_23_P83368

A_24_P116606

A_33_P3305023

GE62832

GO:0000122

GO:0001649

GO:0003674

GO:0003713

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005794

GO:0005829

GO:0005886

GO:0005902

GO:0006915

GO:0007165

GO:0007267

GO:0008150

GO:0008219

GO:0009058

GO:0016055

GO:0016491

GO:0019899

GO:0030154

GO:0030178

GO:0032991

GO:0034641

GO:0043226

GO:0045944

GO:0048705

GO:0048856

GO:0055114

GO:0071560

GO:0072332

GO:0090575

GO:0097191

GO:2001238

GO:2001241

ILMN_1660636

ILMN_1730570

ILMN_1734600

ILMN_1804841

ILMN_2415776

PH_hs_0000063

TC16000631.hg

U13395_at

g13699257_3p_s_at

g538131_3p_s_at

g7706522_3p_a_at

g8927392_3p_s_at

g8927394_3p_at

Participant Of

input

hasComponent

Inferred To

WWOX [cytosol] (Bos taurus)

WWOX [cytosol] (Canis familiaris)

WWOX [cytosol] (Gallus gallus)

WWOX [cytosol] (Sus scrofa)

wwox [cytosol] (Danio rerio)

dhs-7 [cytosol] (Caenorhabditis elegans)

Wwox [cytosol] (Drosophila melanogaster)

Wwox [cytosol] (Mus musculus)

Cross References

RefSeq

NP_001278926.1, NP_057457.1, NP_570607.1

OpenTargets

ENSG00000186153

GeneCards

Q9NZC7

HPA

ENSG00000186153-WWOX

Ensembl

ENST00000566780, ENSP00000384238, ENST00000408984, ENSP00000348119, ENST00000569818, ENST00000355860, ENSP00000386161, ENSP00000384495, ENSP00000454485, ENSP00000457230, ENSG00000186153, ENST00000406884, ENST00000402655

PRO

Q9NZC7

Orphanet

15732

PDB

1WMV

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99732 LITAF			0.61	5
UniProt:Q96G27 WBP1			0.591	3
UniProt:O15350-2 TP73			0.591	5
UniProt:O15350 TP73	3	TP73 [cytosol] (R-HSA-8957239) PolyUb-TP73 [cytosol] (R-HSA-8957256) TP73 [nucleoplasm] (R-HSA-6798094)	0.556	7
UniProt:Q8N114 SHISA5	2	SHISA5 [endoplasmic reticulum lumen] (R-HSA-8956782) p-SHISA5 [endoplasmic reticulum lumen] (R-HSA-8956987)	0.524	2
UniProt:P81408 F189B			0.524	2
UniProt:Q67FY2	1	Bcl9l [nucleoplasm] (R-MMU-3305843)	0.463	3
UniProt:Q61527	14	phospho-Erbb4 [mitochondrial matrix] (R-MMU-1254387) phospho-Erbb4 [mitochondrial matrix] (R-MMU-1254405) phospho-Erbb4 [nucleoplasm] (R-MMU-1252010) phospho-Erbb4 [nucleoplasm] (R-MMU-1252017) phospho-Erbb4 [cytosol] (R-MMU-1251987) phospho-Erbb4 [plasma membrane] (R-MMU-1251984) phospho-Erbb4 [plasma membrane] (R-MMU-1252004) phospho-Erbb4 [cytosol] (R-MMU-1251964) Erbb4 [plasma membrane] (R-MMU-1233232) Erbb4 [plasma membrane] (R-MMU-1233237) Erbb4 [plasma membrane] (R-MMU-1227940) phospho-Erbb4 [plasma membrane] (R-MMU-1250313) phospho-Erbb4 [plasma membrane] (R-MMU-1250307) phospho-Erbb4 [plasma membrane] (R-MMU-1250319)	0.463	3
UniProt:O43493 TGOLN2	8	p-TGOLN2 [endoplasmic reticulum lumen] (R-HSA-8956886) TGOLN2 [endoplasmic reticulum lumen] (R-HSA-8956702) TGOLN2 [transport vesicle] (R-HSA-6811011) TGOLN2 [trans-Golgi network membrane] (R-HSA-6811008) TGOLN2 [cytoplasmic vesicle membrane] (R-HSA-429818) TGOLN2 [Golgi membrane] (R-HSA-434342) TGOLN2 [plasma membrane] (R-HSA-8864458) TGOLN2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869127)	0.462	2
UniProt:P27824 CANX	2	CANX [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.462	2

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