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Cytokine Signaling in Immune system
Stable Identifier
R-HSA-1280215
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
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Cytokines are small proteins that regulate and mediate immunity, inflammation, and hematopoiesis. They are secreted in response to immune stimuli, and usually act briefly, locally, at very low concentrations. Cytokines bind to specific membrane receptors, which then signal the cell via second messengers, to regulate cellular activity.
Literature References
PubMed ID
Title
Journal
Year
COPE
Ibelgaufts, Horst
12613569
Cytokines and chemokines in autoimmune disease: an overview
Santamaria, P
Adv Exp Med Biol
2003
IMMPORT:Bioinformatics for the future of immunology
Wiser, J
,
Scheuermann, R
Cytokine Reference
Feldmann, M
,
Oppenheim, J
2002
Participants
Events
Interferon Signaling
(Homo sapiens)
Signaling by Interleukins
(Homo sapiens)
Growth hormone receptor signaling
(Homo sapiens)
Prolactin receptor signaling
(Homo sapiens)
TNFR2 non-canonical NF-kB pathway
(Homo sapiens)
FLT3 Signaling
(Homo sapiens)
Signaling by CSF3 (G-CSF)
(Homo sapiens)
Signaling by CSF1 (M-CSF) in myeloid cells
(Homo sapiens)
Participates
as an event of
Immune System (Homo sapiens)
Orthologous Events
Cytokine Signaling in Immune system (Bos taurus)
Cytokine Signaling in Immune system (Caenorhabditis elegans)
Cytokine Signaling in Immune system (Canis familiaris)
Cytokine Signaling in Immune system (Danio rerio)
Cytokine Signaling in Immune system (Dictyostelium discoideum)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Cytokine Signaling in Immune system (Gallus gallus)
Cytokine Signaling in Immune system (Mus musculus)
Cytokine Signaling in Immune system (Plasmodium falciparum)
Cytokine Signaling in Immune system (Rattus norvegicus)
Cytokine Signaling in Immune system (Saccharomyces cerevisiae)
Cytokine Signaling in Immune system (Schizosaccharomyces pombe)
Cytokine Signaling in Immune system (Sus scrofa)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Authored
Garapati, P V (2011-05-22)
Jupe, S (2011-05-22)
Ray, KP (2011-05-22)
Reviewed
Abdul-Sater, AA (2011-05-29)
Schindler, C (2011-05-29)
Pinteaux, E (2011-05-29)
Created
Garapati, P V (2011-05-12)
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