B-RAF dissociates from S111/S120 p-SPRY2

Stable Identifier
R-HSA-1295604
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

MAPK-dependent serine phosphorylation of SPRY2 disrupts complex formation with B-RAF.

Literature References
PubMed ID Title Journal Year
19690147 Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation

Brady, SC, Coleman, ML, Munro, J, Feller, SM, Morrice, NA, Olson, MF

Cancer Res 2009
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created