B-RAF dissociates from S111/S120 p-SPRY2

Stable Identifier
R-HSA-1295604
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

MAPK-dependent serine phosphorylation of SPRY2 disrupts complex formation with B-RAF.

Literature References
PubMed ID Title Journal Year
19690147 Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation

Brady, SC, Coleman, ML, Munro, J, Feller, SM, Morrice, NA, Olson, MF

Cancer Res 2009
Participants
Participant Of
Orthologous Events
Authored
Reviewed