Binding of cAMP to HCN channels

Stable Identifier
R-HSA-1297444
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

HCN channels require cAMP binding and hyperpolarization of membrane potential for channel opening.

Literature References
PubMed ID Title Journal Year
11328811 Hyperpolarization-activated cyclic nucleotide-gated channel 1 is a molecular determinant of the cardiac pacemaker current I(f)

Moroni, A, Gorza, L, Beltrame, M, Gravante, B, Vaccari, T, Bianchi, ME, Altomare, C, Longhi, R, Heurteaux, C, Vitadello, M, Malgaroli, A, DiFrancesco, D

J Biol Chem 2001
Participants
Participant Of
hasEvent
Orthologous Events
Authored
Reviewed