TWIK-related alkaline pH activated K+ channel (TALK)

Stable Identifier
R-HSA-1299361
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

TWIK related alkaline pH activated K+ channels are activated by increase in the extracellular pH. TALK1 and TALK 2 are members of the TALK subfamily and are both are activated by rise in extracellular pH. TALK 2 is expressed in proximal tubule cells and collecting duct cells. TASK 2 is involved in the resorption of bicarbonate.

Literature References
PubMed ID Title Journal Year
20393194 Molecular background of leak K+ currents: two-pore domain potassium channels

Enyedi, P, Czirják, G

Physiol Rev 2010
Participants
Participant Of
Orthologous Events
Authored
Reviewed