TWIK-related alkaline pH activated K+ channel (TALK)

Stable Identifier
R-HSA-1299361
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
Click the image above or here to open this pathway in the Pathway Browser

TWIK related alkaline pH activated K+ channels are activated by increase in the extracellular pH. TALK1 and TALK 2 are members of the TALK subfamily and are both are activated by rise in extracellular pH. TALK 2 is expressed in proximal tubule cells and collecting duct cells. TASK 2 is involved in the resorption of bicarbonate.

Literature References
PubMed ID Title Journal Year
20393194 Molecular background of leak K+ currents: two-pore domain potassium channels

Enyedi, P, Czirják, G

Physiol Rev 2010
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created