Reactome | PMPCB [mitochondrial matrix]

PMPCB [mitochondrial matrix]

Stable Identifier

R-HSA-1299434

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Mitochondrial-processing peptidase subunit beta, MPPB_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75439 PMPCB

Gene Names

PMPCB, MPPB

Chain

transit peptide:1-43, chain:44-489

Reference Genes

BioGPS Gene:9512 PMPCB

COSMIC (genes):PMPCB PMPCB

CTD Gene:9512 PMPCB

dbSNP Gene:9512 PMPCB

ENSEMBL:ENSG00000105819 PMPCB

HGNC:9119 PMPCB

KEGG:hsa:9512 PMPCB

Monarch:9512 PMPCB

NCBI Gene:9512 PMPCB

OMIM:603131 PMPCB

UCSC:O75439 PMPCB

Reference Transcript

RefSeq:NM_004279.2 PMPCB

Other Identifiers

11732121_a_at

11732122_at

11760355_a_at

11760356_at

1570542_PM_a_at

1570542_a_at

17049939

201682_PM_at

201682_at

244534_PM_at

244534_at

3017155

3017156

3017157

3017158

3017161

3017162

3017163

3017164

3017165

3017166

3017167

3017168

3017169

3017170

3017171

3017172

3017173

3017174

3017175

3017176

3017177

3017178

3017179

3017180

3017181

3017182

3017183

3017184

3017185

3017186

3017189

3017190

3017191

32167_at

8135235

83021_s_at

83022_r_at

88115_f_at

88117_at

9512

A_14_P114735

A_14_P137807

A_23_P134464

A_33_P3294162

GE61431

GE81374

GE86820

GE888638

GO:0003824

GO:0004222

GO:0005739

GO:0005759

GO:0006508

GO:0006627

GO:0006851

GO:0008237

GO:0016787

GO:0017087

GO:0043226

GO:0046872

GO:0051604

GO:0055085

GO:0140096

HMNXSV003006747

HMNXSV003013311

Hs.147877.0.A1_3p_at

Hs2.156379.1.A1_3p_s_at

ILMN_1728660

PH_hs_0010853

TC07000672.hg

g4758733_3p_at

Participates

as a component of

PMPCB:Zn2+ [mitochondrial matrix] (Homo sapiens)

Inferred To

UQCR-C1 [mitochondrial matrix] (Drosophila melanogaster)

PMPCB [mitochondrial matrix] (Bos taurus)

PMPCB [mitochondrial matrix] (Caenorhabditis elegans)

PMPCB [mitochondrial matrix] (Canis familiaris)

PMPCB [mitochondrial matrix] (Gallus gallus)

PMPCB [mitochondrial matrix] (Mus musculus)

PMPCB [mitochondrial matrix] (Rattus norvegicus)

PMPCB [mitochondrial matrix] (Sus scrofa)

Cross References

ENSEMBL

ENSG00000105819, ENST00000249269, ENSP00000249269

OpenTargets

ENSG00000105819

GeneCards

PMPCB

HPA

ENSG00000105819-PMPCB

PRO

O75439

Pharos - Targets

O75439

GlyGen

O75439

Orphanet

PMPCB

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.643	3
UniProt:Q9HC36 MRM3	1	RNMTL1 [mitochondrial matrix] (R-HSA-6793067)	0.527	2
UniProt:P01160 NPPA	5	NPPA(124-151) [extracellular region] (R-HSA-5578799) NPPA(1-151) [extracellular region] (R-HSA-976950) NPPA(1-25) [extracellular region] (R-HSA-5578791) NPPA(56-123) [extracellular region] (R-HSA-5578797) NPPA(26-55) [extracellular region] (R-HSA-5578794)	0.527	2
UniProt:Q80H93 8b	1	8b [cytosol] (R-COV-9678168)	0.527	2
UniProt:Q9BQB4 SOST	1	SOST [extracellular region] (R-HSA-3769322)	0.527	3