Reactome | ERBIN [plasma membrane]

ERBIN [plasma membrane]

Stable Identifier

R-HSA-1358718

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

ERBB2IP, LAP2

Locations in the PathwayBrowser for interactor UniProt:Q99569 PKP4

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External Reference Information

External Reference

UniProt:Q96RT1 ERBIN

Gene Names

ERBIN, ERBB2IP, KIAA1225, LAP2

Chain

chain:1-1412

Reference Genes

BioGPS Gene:55914 ERBIN

COSMIC (genes):ERBIN ERBIN

CTD Gene:55914 ERBIN

dbSNP Gene:55914 ERBIN

ENSEMBL:ENSG00000112851 ERBIN

HGNC:15842 ERBIN

KEGG:hsa:55914 ERBIN

Monarch:55914 ERBIN

NCBI Gene:55914 ERBIN

OMIM:606944 ERBIN

UCSC:Q96RT1 ERBIN

Reference Transcript

Participates

as a component of

as an output of

as a candidate of

Inferred To

ERBIN [plasma membrane] (Canis familiaris)

Erbin [plasma membrane] (Mus musculus)

Ghost homologue of ERBIN [plasma membrane] (Bos taurus)

Ghost homologue of ERBIN [plasma membrane] (Caenorhabditis elegans)

Ghost homologue of ERBIN [plasma membrane] (Danio rerio)

Ghost homologue of ERBIN [plasma membrane] (Drosophila melanogaster)

Ghost homologue of ERBIN [plasma membrane] (Gallus gallus)

Ghost homologue of ERBIN [plasma membrane] (Rattus norvegicus)

Ghost homologue of ERBIN [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_001006600.1, NP_061165.1, NP_001240627.1, NP_001240630.1, NP_001240626.1, NP_001240628.1

OpenTargets

ENSG00000112851

ENSEMBL

ENSP00000284037, ENST00000284037, ENST00000506030, ENST00000380938, ENSP00000370330, ENSG00000112851, ENST00000508515, ENST00000511297, ENSP00000422766, ENSP00000514078, ENST00000380943, ENSP00000426632, ENSP00000514079, ENSP00000370325, ENSP00000422015, ENST00000699001, ENST00000699000

HPA

ENSG00000112851-ERBIN

GeneCards

ERBIN

PRO

Q96RT1

Pharos - Targets

Q96RT1

Orphanet

ERBIN

GlyGen

Q96RT1

PDB

6Q0N, 6Q0M, 3CH8, 2QBW, 6UBH, 2H3L, 1MFL, 7LUL, 1N7T, 1MFG, 6Q0U

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.671	6
UniProt:Q9HC29 NOD2	1	NOD2 [cytosol] (R-HSA-168411)	0.664	5
UniProt:Q9UQ13 SHOC2	4	SHOC2 [cytosol] (R-HSA-9658444) SHOC2 M173I [cytosol] (R-HSA-9660486) SHOC2 Q269_H270delinsHY [cytosol] (R-HSA-9660464) SHOC2 S2G [cytosol] (R-HSA-9660457)	0.623	4
UniProt:Q99569 PKP4	2	PKP4 [cornified envelope] (R-HSA-8847721) PKP4 [plasma membrane] (R-HSA-6814401)	0.621	4
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.569	3
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.483	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	7
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.483	3