GHBP binds GHR

Stable Identifier
R-HSA-1362465
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

GHBP, the ectodomain of GHR cleaved from membrane-bound GHR can form a heterodimer with GHR. This is not capable of signaling and may be a negative regulatory influence. GHBP can also inhibit signaling by competing with the full length receptor for GH binding.

Participants
Participant Of
Orthologous Events