factor V -> factor Va + factor V activation peptide

Stable Identifier
R-HSA-140696
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Activated thrombin (factor IIa) catalyzes the conversion of factor V to factor Va (activated factor V). The activation peptide released in this reaction has no known function.

Literature References
PubMed ID Title Journal Year
14982929 The factor V activation paradox

Orfeo, T, Brufatto, N, Nesheim, ME, Xu, H, Butenas, S, Mann, KG

J Biol Chem 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
serine-type endopeptidase activity of activated thrombin (factor IIa) [extracellular region]
Physical Entity
Activity
This event is regulated
Orthologous Events
Authored
Created