antithrombin III + heparin -> antithrombin III:heparin

Stable Identifier
R-HSA-140806
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Antithrombin III binds to membrane-associated heparin, e.g., on the surface of a normal endothelial cell. This binding event increases the affinity of antithrombin III for thrombin approximately 1000-fold.

Literature References
PubMed ID Title Journal Year
12907439 Heparin-induced substrate behavior of antithrombin Cambridge II

Mushunje, A, Zhou, A, Carrell, RW, Huntington, JA

Blood 2003
Participants
Participant Of
Orthologous Events
Authored
Created