TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa

Stable Identifier
R-HSA-140825
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
Inactivation of factor VIIa by TFPI
ReviewStatus
5/5
Locations in the PathwayBrowser
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TFPI binds to the factor VIIa:TF complex and to factor Xa at the endothelial surface, forming a stable heterotetrameric complex in which factor VIIa is catalytically inactive.
Literature References
PubMed ID Title Journal Year
2271516 Regulation of coagulation by a multivalent Kunitz-type inhibitor

Novotny, WF, Girard, TJ, Broze, GJ Jr

Biochemistry 1990
Participants
Participates
Event Information
Orthologous Events
Authored
Created
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