Reactome: A Curated Pathway Database

TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10

Stable Identifier
R-HSA-141316
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Caspase-10 precursor is recruited to the TRAIL:TRAIL receptor-2:FADD complex (TNFSF10:TNFRSF10B:FADD) as well as TRAIL:TRAIL receptor-1:FADD complex (TNFSF10:TNFRSF10A:FADD) (Sprick et al. 2002) through interaction of death effector domains of caspase-10 and FADD (Wang et al. 2001).

Literature References
Participants
Participant Of
hasEvent
Orthologous Events