Mad1 binds kinetochore

Stable Identifier
R-HSA-141409
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Mad1 binds kinetochore
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The association of Mad1 with the kinetochore is the first step in the process of Mad2 mediated amplification of the signal from defective kinetochores.

Literature References
PubMed ID Title Journal Year
11181178 Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase

Campbell, MS, Chan, GK, Yen, TJ

J Cell Sci 2001
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
Mad1 binds kinetochore (Canis familiaris)
Mad1 binds kinetochore (Danio rerio)
Mad1 binds kinetochore (Gallus gallus)
Mad1 binds kinetochore (Mus musculus)
Mad1 binds kinetochore (Rattus norvegicus)
Mad1 binds kinetochore (Sus scrofa)
Authored
Yen, TJ  (2004-05-05)
Created
Yen, TJ  (2004-05-05)
Cite Us!