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factor V [platelet alpha granule lumen]
Stable Identifier
R-HSA-141766
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule lumen
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Exocytosis of platelet alpha granule contents (Homo sapiens)
Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)
factor V [platelet alpha granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12259 F5
Gene Names
F5
Chain
signal peptide:1-28, chain:29-2224, chain:29-737, propeptide:738-1573, chain:1574-2224
Reference Genes
BioGPS Gene:2153 F5
COSMIC (genes):F5 F5
CTD Gene:2153 F5
dbSNP Gene:2153 F5
ENSEMBL:ENSG00000198734 F5
HGNC:3542 F5
KEGG Gene (Homo sapiens):2153 F5
Monarch:2153 F5
NCBI Gene:2153 F5
OMIM:612309 F5
UCSC:P12259 F5
Reference Transcript
RefSeq:NM_000130.4 F5
Other Identifiers
0006200270
11723553_at
11723554_at
11751042_a_at
11758395_s_at
16696187
204713_s_at
204714_s_at
2153
231029_at
2443369
2443371
2443372
2443373
2443374
2443375
2443377
2443378
2443381
2443382
2443383
2443384
2443385
2443386
2443388
2443389
2443391
2443392
2443393
2443394
2443395
2443396
2443397
2443398
2443399
2443400
2443402
2443403
2443404
2443405
2443406
2443407
2443408
2443410
2443412
2443413
2443414
2443415
35245_at
62710_at
7922174
A_23_P148768
A_32_P41604
GE57848
GO:0002576
GO:0003013
GO:0003674
GO:0005507
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0005886
GO:0006464
GO:0006810
GO:0006888
GO:0006950
GO:0007596
GO:0007599
GO:0008015
GO:0008150
GO:0016020
GO:0016192
GO:0022607
GO:0030134
GO:0031091
GO:0031093
GO:0031410
GO:0033116
GO:0043167
GO:0043226
GO:0043687
GO:0044267
GO:0046872
GO:0048208
GO:0061024
GO:0065003
GO:1903561
HMNXSV003023557
Hs.165077.0.A1_3p_at
Hs.30054.0.S1_3p_a_at
ILMN_1709233
M16967_at
PH_hs_0002589
PH_hs_0020466
TC01003498.hg
g10518500_3p_a_at
Participates
as a member of
Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)
Other forms of this molecule
F5(535-737) [extracellular region]
F5(335-534) [extracellular region]
F5(29-334) [extracellular region]
F5(29-534) [extracellular region]
factor V activation peptide [extracellular region]
Factor V precursor [endoplasmic reticulum lumen]
p-Factor V precursor [endoplasmic reticulum lumen]
Factor V precursor [COPII-coated ER to Golgi transport vesicle]
Factor V precursor [endoplasmic reticulum-Golgi intermediate compartment membrane]
factor Va light chain [plasma membrane]
factor Va heavy chain [plasma membrane]
factor Va light chain [extracellular region]
factor Va heavy chain [extracellular region]
factor V [extracellular region]
Inferred To
F5 [platelet alpha granule lumen]
(Bos taurus)
F5 [platelet alpha granule lumen]
(Canis familiaris)
F5 [platelet alpha granule lumen]
(Gallus gallus)
F5 [platelet alpha granule lumen]
(Mus musculus)
F5 [platelet alpha granule lumen]
(Sus scrofa)
f5 [platelet alpha granule lumen]
(Danio rerio)
factor V [platelet alpha granule lumen]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000121.2
Guide to Pharmacology - Targets
2606
OpenTargets
ENSG00000198734
ZINC - Substances
FA5_HUMAN
ZINC target
P12259
PRO
P12259
GlyGen
P12259
PDB
3P6Z
,
3S9C
,
1CZV
,
7KVE
,
3P70
,
7KVF
,
1CZT
,
7KXY
,
1CZS
GeneCards
P12259
HPA
ENSG00000198734-F5
Ensembl
ENSG00000198734
,
ENSP00000356771
,
ENST00000367797
Pharos - Targets
P12259
ZINC - Predictions - Purchasable
FA5_HUMAN
Orphanet
16014
HMDB Protein
HMDBP02118
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