JAK2 binds to p-KIT

Stable Identifier
R-HSA-1433451
Type
Reaction
Species
Homo sapiens
Compartment
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Janus kinase 2 (JAK2) plays an important role in SCF-induced proliferation (Radosevic et al. 2004). JAK2 was observed to pre-associate with KIT, with increased association after SCF stimulation of KIT (Weiler et al. 1996).

Literature References
PubMed ID Title Journal Year
8611693 JAK2 is associated with the c-kit proto-oncogene product and is phosphorylated in response to stem cell factor

Weiler, SR, Mou, S, DeBerry, CS, Keller, JR, Ruscetti, FW, Ferris, DK, Longo, DL, Linnekin, D

Blood 1996
Participants
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Orthologous Events
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