Phosphorylation of GAB2 by SFKs

Stable Identifier
R-HSA-1433454
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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GAB2 bound to GRB2 on KIT is then phosphorylated on a number of tyrosine residues through the action of Src family kinases (SFKs).

Literature References
PubMed ID Title Journal Year
18697750 Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit

Sun, J, Pedersen, M, Rönnstrand, L

J Biol Chem 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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