Interaction of other adapter proteins with p-KIT

Stable Identifier
R-HSA-1433501
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Adapter proteins GADS, GRAP, GRB7 and GRB10 interact with activated KIT (Liu & McGlade 1998, Feng et al. 1996, Thömmes et al. 1999, Jahn et al. 2002).

Literature References
PubMed ID Title Journal Year
9872323 Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

Liu, SK, McGlade, CJ

Oncogene 1998
8647802 Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway

Feng, GS, Ouyang, YB, Hu, DP, Shi, ZQ, Gentz, R, Ni, J

J Biol Chem 1996
10377264 Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

Thömmes, K, Lennartsson, J, Carlberg, M, Rönnstrand, L

Biochem J 1999
11809791 Role for the adaptor protein Grb10 in the activation of Akt

Jahn, T, Seipel, P, Urschel, S, Peschel, C, Duyster, J

Mol Cell Biol 2002
16129412 Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

Roskoski, R Jr

Biochem Biophys Res Commun 2005
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created