Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GRB2:p-SHP2:p-KIT complex [plasma membrane]
Stable Identifier
R-HSA-1433549
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
GRB2:p-SHP2:SFKs:p-7Y-KIT:sSCF dimer:p-7Y-KIT
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by SCF-KIT (Homo sapiens)
GRB2 is indirectly recruited to p-KIT through SHP2 (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
Indirect recruitment of GAB2 to p-KIT (Homo sapiens)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Homo sapiens)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation of GAB2 by SFKs (Homo sapiens)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
Synthesis of PIP3 from PIP2 by PI3K (Homo sapiens)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
Participants
components
GRB2-1 [cytosol]
(Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane]
(Homo sapiens)
Participates
as an output of
GRB2 is indirectly recruited to p-KIT through SHP2 (Homo sapiens)
as an input of
Indirect recruitment of GAB2 to p-KIT (Homo sapiens)
as a component of
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
Inferred To
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Bos taurus)
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Danio rerio)
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Mus musculus)
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Rattus norvegicus)
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Sus scrofa)
GRB2:p-SHP2:p-KIT complex [plasma membrane]
(Xenopus tropicalis)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text