SFN [cytosol]

Stable Identifier
R-HSA-1445105
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
14-3-3 sigma, 14-3-3 protein sigma, 1433S_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q13322 GRB10
External Reference Information
External Reference
Gene Names
SFN, HME1
Chain
chain:1-248
Reference Transcript
Other Identifiers
11717576_a_at
16661314
209260_PM_at
209260_at
2326775
2326776
2326777
2326778
2326779
2326780
2810
33322_3p_i_at
33322_PM_i_at
33322_i_at
33323_PM_r_at
33323_r_at
75288_at
7899265
A_14_P133833
A_23_P63254
A_33_P3389286
GE79528
GO:0000122
GO:0001836
GO:0003334
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006469
GO:0006611
GO:0006886
GO:0006913
GO:0007005
GO:0007165
GO:0008426
GO:0008630
GO:0010482
GO:0010737
GO:0010839
GO:0012501
GO:0019901
GO:0023052
GO:0030154
GO:0030216
GO:0030307
GO:0031424
GO:0036211
GO:0042802
GO:0043154
GO:0043226
GO:0043588
GO:0043616
GO:0045296
GO:0045606
GO:0046827
GO:0048856
GO:0051219
GO:0051726
GO:0061436
GO:0070062
GO:0072089
GO:0098772
GO:2000647
HMNXSV003053202
ILMN_1806607
PH_hs_0029373
PH_hs_0030806
TC01000353.hg
X57348_s_at
g12653124_3p_at
g12653124_3p_x_at
Participates
Inferred To
Cross References
RefSeq
OpenTargets
GeneCards
ZINC target
PRO
Pharos - Targets
PDB
7NSV, 7B15, 6ZCJ, 6SLX, 7BIW, 6FI4, 8AXE, 6RWI, 8AQC, 4DHU, 7OPW, 4DHR, 6YLU, 7BJF, 7O07, 7OBL, 8APS, 8AR4, 8BZ9, 6RHC, 7NPB, 7OQW, 7O3P, 7NJ9, 6HKF, 8B4Q, 7OQS, 8BZW, 7BDY, 5OMA, 7OB5, 8BXM, 6YOW, 8ATR, 3MHR, 6SIP, 7O5S, 8C4F, 6FBW, 8B2I, 7AOG, 7OBG, 7B9M, 6GHP, 8BY9, 7AZ2, 3SMN, 7BGQ, 6G8J, 6FBB, 1YZ5, 8BJG, 4JDD, 7AXN, 7BAB, 8BYZ, 8BX0, 4DHN, 7O6I, 7OQ7, 7ORG, 7NJB, 6SLW, 8ATP, 7NXT, 6Y3M, 7BA3, 7BKH, 7O5A, 8ARO, 6G8P, 6QDT, 8BM5, 7OR5, 7NMH, 6HN2, 6RX2, 3U9X, 6Y44, 7O5G, 5LTW, 3IQV, 8BI7, 4JC3, 6YR6, 8AFN, 6RKK, 8C3C, 3SMM, 8AU2, 7O5X, 7OQA, 5N5T, 7NM9, 7OQ8, 7NXW, 6YPY, 8BYC, 6SIO, 6RL6, 5HF3, 6RJZ, 6QDU, 4Y5I, 7AEW, 7O57, 7O6F, 5MHC, 7NIG, 8BXO, 7O5O, 5MYC, 7OQ9, 6Y3R, 7O5C, 7BMC, 6G8Q, 8ARY, 6TLG, 8BYO, 5OK9, 6Y58, 8AQE, 6YE9, 8AV8, 8ALT, 6YIA, 8AQ1, 7NJA, 6T5F, 6Y7T, 7OBS, 6RKM, 7BJL, 6YQ2, 7BFW, 7NN2, 7NPG, 7O59, 6FI5, 8B2K, 8A6F, 8BXN, 3UX0, 6Y8E, 5MOC, 8C2G, 8AM7, 4DHS, 3T0L, 7NXY, 3P1S, 8AT9, 6Y18, 6QDR, 7BDP, 6R5L, 6G8K, 7OBD, 7O6O, 5LU1, 8AV4, 8ARW, 7O5F, 5N5W, 6RJL, 7NZV, 7BGW, 8C4G, 7OB8, 6YP3, 6TLF, 7BA5, 7NRK, 8C0K, 4DAT, 7OBH, 8C2D, 7BA8, 6Y3W, 7OQG, 7OBT, 3P1R, 7NYG, 7NM1, 8BX3, 6RM5, 6YR7, 3SPR, 7O3S, 4Y32, 6XWD, 7OBY, 6FAU, 8BWJ, 6Y3O, 6W0L, 8AS1, 7NLA, 7O3A, 7NWS, 6ZVC, 6Y8D, 7NK3, 6RK8, 7BM9, 3IQJ, 7NRL, 8ANC, 7NYE, 7NZG, 8BZA, 7QIK, 5MXO, 7NJ6, 6HMT, 8BXQ, 8AXU, 6S39, 3SMK, 7NNE, 8AV0, 5OKF, 6S3C, 6RL3, 8BYY, 5BTV, 6FBY, 8ARQ, 7ORH, 1YWT, 5OEG, 3LW1, 4DAU, 8ARZ, 6YOX, 6Y3S, 5N75, 6QZR, 6XXC, 6RWU, 7O5U, 7O3F, 6YR5, 7NP2, 8ANB, 7OR7, 6RKI, 7NXS, 7BGR, 6TCH, 8BYD, 6RM7, 7ZMU, 6RL4, 8A6H, 7BJW, 8AUS, 8ALV, 4DHT, 7BA6, 8ARX, 3SMO, 8AR5, 8AV7, 7BJB, 7BDT, 8Q4L, 3P1Q, 4FR3, 8ALR, 7NV4, 8BZ0, 8BFC, 7O3Q, 7OBX, 7BI3, 6YP8, 6QHL, 7BIY, 7NIX, 7B9R, 6NV2, 6RWS, 7NVI, 6G6X, 4FL5, 4IEA, 8BYF, 8A65, 7NFW, 4DHO, 8BX4, 8BWX, 6T5H, 7OBC, 3SML, 3P1P, 6FAV, 6SIN, 8ANF, 7OBK, 6TWZ, 7O6J, 7NMW, 8AOY, 7O6G, 6SIQ, 8BXI, 6HHP, 6QHM, 6ZVD, 7AYF, 8AWG, 7ORT, 7NMA, 7BA9, 7NJ8, 4DHP, 5LU2, 8C04, 3O8I, 8AI0, 6Y1D, 7PWZ, 6SLV, 8BWZ, 6T80, 7PWT, 6YP2, 3P1N, 7BIQ, 6Y8B, 3T0M, 6Y3V, 7NK5, 4Y3B, 6Y40, 4DHQ, 7O6K, 7OQU, 7NZK, 6FCP, 4QLI, 6YIC, 7NQP, 8A62, 7NYF, 6TL3, 7BGV, 7ORS, 8BYE, 8AQZ, 8AUY, 7BG3, 6Y1J, 7O3R, 7NMX, 3P1O, 6ZVB, 6RWH, 5OEH, 7OR8, 8ARG, 7QIP, 6S9Q, 7OQJ, 7NY4, 6ZVE, 5OM0, 7NZ6, 7BA7, 8BZB, 7O5D, 8BXS, 7NR7, 8B39, 3IQU, 6FAW, 7BAA, 6Y8A, 6HKB, 4DHM, 7ZMW, 6RJQ, 7O34, 7NM3, 8ALW, 8A68, 6S40, 8B5P, 6YOY, 5MY9, 3SP5, 7AZ1, 6HMU, 8BYG, 7B9T, 6YIB, 6TM7, 6G8I, 8ATS, 7OR3, 7B13, 6XY5, 8BYB, 5N5R, 7NIZ, 6TJM, 7O5P, 6RP6, 6QDS, 7O6M, 6G8L, 7NLE, 6QZS, 8BJN, 7NND, 7NIF, 6QIU, 6YPL, 8ADM, 8ARR, 8AV3, 8AZE
Interactors (134)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  20 0.887 9
 UniProt:Q92934 BAD  4 0.873 8
 UniProt:P00533 EGFR  20 0.833 9
 UniProt:P56524 HDAC4  3 0.783 8
 UniProt:P10398 ARAF  4 0.758 4
 UniProt:P31947 SFN  1 0.756 5
 UniProt:P04637 TP53  20 0.738 5
 UniProt:P63104 YWHAZ  2 0.731 6
 UniProt:P27448 MARK3  1 0.72 5
 UniProt:Q8NHY2 RFWD2  3 0.718 6
 UniProt:P15056 BRAF  20 0.713 5
 UniProt:Q5S007 LRRK2  1 0.713 5
 UniProt:Q8WUI4 HDAC7  1 0.688 3
 UniProt:Q9Y2U5 M3K2      0.688 3
 UniProt:Q13470 TNK1      0.688 3
 UniProt:P30305 CDC25B  3 0.688 3
 UniProt:P98177 FOXO4  8 0.675 4
 UniProt:P00519 ABL1  5 0.667 5
 UniProt:P30291 WEE1  3 0.667 5
 UniProt:Q96HA8 NTAQ1      0.666 4
 UniProt:P51946 CCNH  1 0.666 4
 UniProt:Q7L5N1 COPS6  2 0.653 7
 UniProt:O00444 PLK4  1 0.646 3
 UniProt:Q9H2C0 GAN  1 0.641 3
 UniProt:Q99959 PKP2  2 0.628 5
 UniProt:O96013 PAK4  1 0.628 5
 UniProt:O75494 SRSF10  1 0.628 3
 UniProt:Q9UPU9 SMAG1      0.628 4
 UniProt:P40818 USP8  2 0.628 5
 UniProt:O14639 ABLIM1  1 0.628 5
 UniProt:Q5VV41 ARHGEF16  1 0.628 5
 UniProt:Q9H0B6 KLC2  1 0.628 5
 UniProt:Q86W92 PPFIBP1  5 0.628 4
 UniProt:Q5T1R4 HIVEP3  1 0.618 5
 UniProt:Q9UQC2 GAB2  5 0.615 6
 UniProt:P62258 YWHAE  1 0.604 5
 UniProt:Q14103-4 HNRNPD  2 0.602 7
 UniProt:O15151 MDM4  5 0.589 2
 UniProt:Q6ICG6 K0930      0.589 2
 UniProt:Q86X27 RGPS2      0.589 2
 UniProt:Q86YV5 SGK223  1 0.589 2
 UniProt:P35568 IRS1  5 0.589 2
 UniProt:Q9H1K1 ISCU  1 0.589 2
 UniProt:O60269 GRIN2      0.573 2
 UniProt:P49815 TSC2  4 0.571 3
 UniProt:Q08881 ITK  3 0.564 2
 UniProt:Q6NUK4 REEP3      0.564 2
 UniProt:O95382 M3K6      0.564 2
 UniProt:P22681 CBL  20 0.564 2
 UniProt:Q9H093 NUAK2      0.564 2
 UniProt:P61981 YWHAG  1 0.564 2
 UniProt:Q16288 NTRK3  6 0.564 2
 UniProt:Q02156 PRKCE  2 0.564 2
 UniProt:Q13322 GRB10  2 0.564 2
 UniProt:P10636-2 MAPT      0.558 2
 UniProt:Q86Z20 CC125      0.556 3
 UniProt:Q9NYF3 FA53C      0.556 3
 UniProt:Q17RB8 LONRF1  1 0.556 3
 UniProt:Q8IZU0 FAM9B      0.556 3
 UniProt:Q68D86 C102B      0.556 3
 UniProt:P43355 MAGA1      0.556 3
 UniProt:Q9UJM3 ERRFI      0.556 3
 UniProt:Q13064 MKRN3      0.556 3
 UniProt:Q53FD0 ZC21C      0.556 3
 UniProt:P55771 PAX9      0.556 3
 UniProt:Q03373 DIG2      0.556 3
 UniProt:Q96QF0 RAB3IP  1 0.556 3
 UniProt:Q9UQL6 HDAC5  1 0.547 3
 UniProt:Q8NFH8 REPS2  1 0.544 2
 UniProt:Q6R327 RICTOR  1 0.536 4
 UniProt:Q5T5U3 ARHGAP21  1 0.536 4
 UniProt:Q96F86 EDC3  1 0.536 4
 UniProt:O94885 SASH1      0.536 4
 UniProt:Q9P2M7 CGN  1 0.536 4
 UniProt:P56945 BCAR1  4 0.536 2
 UniProt:Q6P1L5 F117B      0.536 4
 UniProt:O94875 SRBS2      0.536 4
 UniProt:Q9P0V3 SH3BP4  1 0.536 2
 UniProt:Q92625 ANS1A      0.536 4
 UniProt:Q02241 KIF23  3 0.536 4
 UniProt:P78524 ST5  1 0.536 2
 UniProt:Q8TF72 SHRM3      0.536 2
 UniProt:Q9NYL2 M3K20      0.536 4
 UniProt:Q8TEW8 PAR3L      0.536 2
 UniProt:O15056 SYNJ2  1 0.536 2
 UniProt:Q9H6H4 REEP4      0.536 4
 UniProt:Q8TEW0 PARD3  3 0.536 4
 UniProt:A7KAX9 ARHGAP32  1 0.536 3
 UniProt:Q12774 ARHGEF5  1 0.536 4
 UniProt:O75592 MYCB2      0.536 4
 UniProt:O00750 PIK3C2B  1 0.536 4
 UniProt:O60292 SI1L3      0.536 4
 UniProt:P33176 KIF5B  3 0.536 2
 UniProt:Q6WCQ1 MPRIP  2 0.536 3
 UniProt:P25054 APC  20 0.536 2
 UniProt:O43166 SIPA1L1  1 0.536 3
 UniProt:Q9Y4H2 IRS2  4 0.536 4
 UniProt:P13569 CFTR  17 0.527 15
 UniProt:Q96IF1 AJUBA  3 0.524 2
 UniProt:Q16352 AINX      0.499 2
 UniProt:Q7Z6J0 SH3RF1  1 0.499 2
 UniProt:P25685 DNAJB1  3 0.499 2
 UniProt:Q04917 YWHAH  1 0.483 4
 UniProt:P10636 MAPT  3 0.483 2
 UniProt:Q9UQB8 BAIAP2  1 0.471 4
 UniProt:Q9NSK0 KLC4  1 0.471 4
 UniProt:Q8IVT5 KSR1  5 0.471 2
 UniProt:Q6PKG0 LARP1  1 0.471 4
 UniProt:Q96PU5 NEDD4L  2 0.471 2
 UniProt:O60343 TBC1D4  2 0.471 4
 UniProt:Q86V48 LUZP1      0.471 4
 UniProt:Q6IQ23 PKHA7      0.471 4
 UniProt:Q9Y3R0 GRIP1  2 0.471 2
 UniProt:Q8N8E3 CE112      0.471 2
 UniProt:Q96S53 TESK2      0.471 2
 UniProt:O43379 WDR62      0.471 4
 UniProt:O14654 IRS4  2 0.471 4
 UniProt:O43491 EPB41L2  1 0.471 3
 UniProt:Q7Z460 CLASP1  1 0.471 3
 UniProt:Q92974 ARHGEF2  1 0.471 4
 UniProt:Q8NEY1 NAV1      0.471 4
 UniProt:O95819 MAP4K4  1 0.471 2
 UniProt:Q6P0Q8 MAST2      0.471 2
 UniProt:Q8N4C8 MINK1  1 0.471 3
 UniProt:O60333 KIF1B  1 0.471 4
 UniProt:Q9H4A3 WNK1  1 0.471 4
 UniProt:O75122 CLASP2  1 0.471 4
 UniProt:Q15750 TAB1  6 0.471 2
 UniProt:P46937 YAP1  7 0.471 2
 UniProt:P47974 ZFP36L2  1 0.471 4
 UniProt:Q14671 PUM1  1 0.471 4
 UniProt:O43524 FOXO3  9 0.471 3
 UniProt:Q51451 Q51451      0.469 2
 UniProt:P06493 CDK1  11 0.463 2
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