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What is Reactome ?
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Table of Contents
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SFN [cytosol]
Stable Identifier
R-HSA-1445105
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
14-3-3 sigma, 14-3-3 protein sigma, 1433S_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q8WUI4 HDAC7
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Homo sapiens)
SFN dimerizes (Homo sapiens)
SFN [cytosol] (Homo sapiens)
TP53 stimulates SFN expression (Homo sapiens)
SFN [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P31947 SFN
Gene Names
SFN, HME1
Chain
chain:1-248
Reference Genes
BioGPS Gene:2810 SFN
COSMIC (genes):SFN SFN
CTD Gene:2810 SFN
dbSNP Gene:2810 SFN
ENSEMBL:ENSG00000175793 SFN
HGNC:10773 SFN
KEGG Gene (Homo sapiens):2810 SFN
Monarch:2810 SFN
NCBI Gene:2810 SFN
OMIM:601290 SFN
UCSC:P31947 SFN
Reference Transcript
RefSeq:NM_006142.3 SFN
Other Identifiers
0001230056
11717576_a_at
16661314
209260_at
2326775
2326776
2326777
2326778
2326779
2326780
2810
33322_3p_i_at
33322_i_at
33323_r_at
75288_at
7899265
A_14_P133833
A_23_P63254
A_33_P3389286
GE79528
GO:0000079
GO:0000278
GO:0001836
GO:0003334
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005739
GO:0005829
GO:0006464
GO:0006469
GO:0006810
GO:0006913
GO:0006950
GO:0006977
GO:0007005
GO:0007049
GO:0007165
GO:0008150
GO:0008219
GO:0008283
GO:0008426
GO:0008630
GO:0010482
GO:0010839
GO:0015031
GO:0019899
GO:0019901
GO:0030154
GO:0030216
GO:0030234
GO:0030307
GO:0031424
GO:0040007
GO:0042592
GO:0042802
GO:0043154
GO:0043226
GO:0043588
GO:0045296
GO:0045606
GO:0046827
GO:0048856
GO:0051219
GO:0051301
GO:0051726
GO:0061024
GO:0061436
GO:0070062
GO:0071901
GO:1900740
ILMN_1806607
PH_hs_0029373
PH_hs_0030806
TC01000353.hg
X57348_s_at
g12653124_3p_at
g12653124_3p_x_at
Participant Of
output
TP53 stimulates SFN expression
input
SFN dimerizes
hasComponent
SFN dimer [cytosol]
SFN Dimer [cytosol]
Inferred To
14-3-3 sigma [cytosol] (Mus musculus)
Sfn [cytosol] (Rattus norvegicus)
14-3-3zeta [cytosol] (Drosophila melanogaster)
par-5 [cytosol] (Caenorhabditis elegans)
ywhaqb [cytosol] (Danio rerio)
ywhaq [cytosol] (Xenopus tropicalis)
Homologues of SFN [cytosol] (Caenorhabditis elegans)
Homologues of SFN [cytosol] (Danio rerio)
SFN [cytosol] (Bos taurus)
SFN [cytosol] (Canis familiaris)
SFN [cytosol] (Gallus gallus)
SFN [cytosol] (Plasmodium falciparum)
ywhaqa [cytosol] (Danio rerio)
ftt-2 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
NP_006133.1
OpenTargets
ENSG00000175793
HPA
ENSG00000175793-SFN
GeneCards
P31947
ZINC target
P31947
Ensembl
ENSP00000340989
,
ENSG00000175793
,
ENST00000339276
PRO
P31947
PDB
3SMO
,
6RL4
,
6QDU
,
6FBB
,
6SLX
,
6SIQ
,
6G8K
,
6TJM
,
5MYC
,
5N5R
,
3IQJ
,
3P1R
,
4QLI
,
5N5W
,
3SPR
,
6TCH
,
3SML
,
6TM7
,
6G8L
,
6S39
,
6Y1J
,
3SMK
,
6HN2
,
5LU1
,
6GHP
,
4DHS
,
6TWZ
,
6RP6
,
4DAU
,
4Y5I
,
6FI5
,
3T0L
,
6RWU
,
4DHP
,
1YZ5
,
6RJQ
,
6S40
,
3P1S
,
4DHO
,
6RJZ
,
5MOC
,
4Y32
,
4JDD
,
6QZR
,
4DHT
,
6FAU
,
3UX0
,
3P1P
,
6RWS
,
6W0L
,
6RKK
,
6FAV
,
6FBY
,
3O8I
,
6RHC
,
6QDR
,
6QDS
,
3IQV
,
6SIP
,
6RKM
,
6QIU
,
6SLV
,
6SIO
,
6G8I
,
6RM5
,
6S9Q
,
5MY9
,
5N75
,
5HF3
,
6RWH
,
1YWT
,
3SMN
,
5BTV
,
5OM0
,
6G8J
,
5OEG
,
6TLG
,
3LW1
,
6RL6
,
3SMM
,
5N5T
,
6FBW
,
6S3C
,
3P1Q
,
5OEH
,
6HMT
,
6R5L
,
5OMA
,
5LU2
,
6G8P
,
6RKI
,
4DHR
,
3T0M
,
6G8Q
,
6HMU
,
6FI4
,
4FR3
,
3SP5
,
6NV2
,
6RJL
,
6TLF
,
4DHQ
,
3U9X
,
6HKB
,
6RX2
,
5OK9
,
6RK8
,
4DHN
,
6G6X
,
6HKF
,
6QZS
,
6QHM
,
4DHU
,
4DHM
,
6RWI
,
5OKF
,
4Y3B
,
5LTW
,
6TL3
,
6SIN
,
3P1O
,
4IEA
,
6HHP
,
6FAW
,
4FL5
,
4JC3
,
3IQU
,
6RM7
,
5MHC
,
5MXO
,
3P1N
,
4DAT
,
3MHR
,
6SLW
,
6QHL
,
6FCP
,
6QDT
,
6RL3
Interactors (44)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00533 EGFR
59
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR M766_A767insASV [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR D770_N771insNPH [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR V738_K739insKIPVAI [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
p-6Y-EGFR A289V [plasma membrane]
(R-HSA-1996334)
p-6Y-EGFR T263P [plasma membrane]
(R-HSA-1996336)
p-6Y-EGFR G598V [plasma membrane]
(R-HSA-1996339)
p-6Y-EGFR R108K [plasma membrane]
(R-HSA-1996338)
p-6Y-EGFR A289T [plasma membrane]
(R-HSA-1996341)
p-6Y-EGFR G719C [plasma membrane]
(R-HSA-1177530)
p-6Y-EGFR A289D [plasma membrane]
(R-HSA-1996340)
p-6Y-EGFR G719A [plasma membrane]
(R-HSA-1177528)
EGFR L858R;T790M [plasma membrane]
(R-HSA-1181386)
EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1181399)
EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996322)
EGFR V738_K739insKIPVAI [plasma membrane]
(R-HSA-1996325)
EGFR M766_A767insASV [plasma membrane]
(R-HSA-1996326)
EGFR D770_N771insNPH [plasma membrane]
(R-HSA-1996317)
EGFR L858R [plasma membrane]
(R-HSA-1173212)
EGFR G719S [plasma membrane]
(R-HSA-1169418)
EGFR E746_A750del [plasma membrane]
(R-HSA-1181211)
EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228010)
EGFR A289V [plasma membrane]
(R-HSA-1996321)
EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228012)
EGFR L747_T751del [plasma membrane]
(R-HSA-1228015)
EGFR A289D [plasma membrane]
(R-HSA-1996327)
EGFR L861Q [plasma membrane]
(R-HSA-1177542)
EGFR R108K [plasma membrane]
(R-HSA-1996330)
EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228034)
EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228031)
EGFR G719A [plasma membrane]
(R-HSA-1177532)
EGFR A289T [plasma membrane]
(R-HSA-1996306)
EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228025)
EGFR G719C [plasma membrane]
(R-HSA-1177531)
EGFR T263P [plasma membrane]
(R-HSA-1996315)
EGFR G598V [plasma membrane]
(R-HSA-1996314)
EGFR L747_S752del [plasma membrane]
(R-HSA-1228016)
EGFR [endosome membrane]
(R-HSA-9611160)
p-4Y-EGFR [plasma membrane]
(R-HSA-180287)
p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane]
(R-HSA-8864019)
p-Y1086,Y1101-EGFR [plasma membrane]
(R-HSA-179868)
EGFR [plasma membrane]
(R-HSA-179837)
p-6Y-EGFR [plasma membrane]
(R-HSA-179803)
0.833
9
UniProt:Q92934 BAD
4
p-S99-BAD [cytosol]
(R-HSA-198335)
BAD [cytosol]
(R-HSA-50662)
BAD [mitochondrial outer membrane]
(R-HSA-114242)
p-S128-BAD [cytosol]
(R-HSA-217297)
0.804
6
UniProt:P04049 RAF1
54
p-S338,Y340,Y341-RAF1 [cytosol]
(R-HSA-5624465)
RAF1 [cytosol]
(R-HSA-167205)
p-S338-RAF1 [cytosol]
(R-HSA-5624469)
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
p-S621-RAF1 G361A [cytosol]
(R-HSA-9656092)
p-S621-RAF1 G370R [cytosol]
(R-HSA-9656094)
p-S621-RAF1 D486G [cytosol]
(R-HSA-9656085)
p-S621-RAF1 T491R [cytosol]
(R-HSA-9656145)
p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol]
(R-HSA-9656026)
p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol]
(R-HSA-9656070)
p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol]
(R-HSA-9656035)
p-S338,Y341,S494,S621-RAF1 T491I [cytosol]
(R-HSA-9656019)
p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol]
(R-HSA-9656029)
p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol]
(R-HSA-9656031)
p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol]
(R-HSA-9656023)
p-S338,Y341,S494,S621 RAF1 T491R [cytosol]
(R-HSA-9656017)
p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol]
(R-HSA-9656062)
p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol]
(R-HSA-9656041)
p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol]
(R-HSA-9656058)
p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol]
(R-HSA-9656043)
p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol]
(R-HSA-9656053)
p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol]
(R-HSA-9656037)
p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol]
(R-HSA-9656050)
p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol]
(R-HSA-9656067)
p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol]
(R-HSA-9656077)
p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol]
(R-HSA-9656047)
p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol]
(R-HSA-9656056)
p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol]
(R-HSA-9656074)
p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol]
(R-HSA-9656080)
p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol]
(R-HSA-9656065)
hyperphosphorylated RAF1 [plasma membrane]
(R-HSA-5675193)
p-S621-RAF1 [plasma membrane]
(R-HSA-206222)
p-Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5675420)
p-S259,S621-RAF1 [cytosol]
(R-HSA-109786)
p-S621-RAF1 [cytosol]
(R-HSA-206028)
p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5672665)
p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-HSA-5672664)
0.744
5
UniProt:Q8NHY2 COP1
3
RFWD2 [nucleoplasm]
(R-HSA-349454)
p-S387-RFWD2 [cytosol]
(R-HSA-349439)
p-S387-RFWD2 [nucleoplasm]
(R-HSA-349450)
0.718
6
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.713
5
UniProt:Q8WUI4 HDAC7
1
HDAC7 [nucleoplasm]
(R-HSA-3004534)
0.688
3
UniProt:P56524 HDAC4
3
SUMO1-K559-HDAC4 [nucleoplasm]
(R-HSA-4616016)
SUMO2,3-K559-HDAC4 [nucleoplasm]
(R-HSA-4616029)
HDAC4 [nucleoplasm]
(R-HSA-351581)
0.678
4
UniProt:P31947 SFN
1
SFN [cytosol]
(R-HSA-1445105)
0.675
4
UniProt:P10398 ARAF
4
p-S299,S302,T452,T455,S576 ARAF [plasma membrane]
(R-HSA-5672648)
p-S299,S302,T452,T455,S576 ARAF [cytosol]
(R-HSA-5672646)
p-S576 ARAF [cytosol]
(R-HSA-5672681)
p-S214,S576 ARAF [cytosol]
(R-HSA-5672639)
0.669
3
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.669
3
UniProt:P04637 TP53
27
TP53 [cytosol]
(R-HSA-8869337)
Unfolded TP53 [cytosol]
(R-HSA-6813797)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
SUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
Me2K-370,382-TP53 [nucleoplasm]
(R-HSA-3222242)
p-S15,S33,S46-TP53 [nucleoplasm]
(R-HSA-6805268)
p-S15,S392-TP53 [nucleoplasm]
(R-HSA-3222015)
p-T55-TP53 [nucleoplasm]
(R-HSA-6805400)
p-S15,S20,S392-TP53 [nucleoplasm]
(R-HSA-6805053)
p-S15,S20,S269,T284-TP53 [nucleoplasm]
(R-HSA-6805133)
p-S315-TP53 [nucleoplasm]
(R-HSA-6805106)
Ac-K120,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805656)
Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805631)
Ac-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-5628868)
Me2-K373-TP53 [nucleoplasm]
(R-HSA-6805759)
MeK-370,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222226)
p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
(R-HSA-6804378)
Me-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222124)
Me1-K372,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805719)
p-S15,S20,S46-TP53 [nucleoplasm]
(R-HSA-6798369)
p-S37-TP53 [nucleoplasm]
(R-HSA-3239022)
PolyUb,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6804446)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6793679)
PolyUb-TP53 [cytosol]
(R-HSA-6793681)
p-S15,S20-TP53 [nucleoplasm]
(R-HSA-69683)
p-S15-TP53 [nucleoplasm]
(R-HSA-69507)
TP53 [nucleoplasm]
(R-HSA-69488)
0.667
4
UniProt:P51946 CCNH
1
CCNH [nucleoplasm]
(R-HSA-69220)
0.666
4
UniProt:Q96HA8 NTAQ1
0.666
4
UniProt:Q7L5N1 COPS6
2
COPS6 [nucleoplasm]
(R-HSA-5697026)
COPS6 [cytosol]
(R-HSA-416961)
0.653
7
UniProt:Q14103-4 HNRNPD
2
HNRNPD-4 [cytosol]
(R-HSA-450442)
Ub-HNRNPD-4 [cytosol]
(R-HSA-451232)
0.602
7
UniProt:P27448 MARK3
1
MARK3 [cytosol]
(R-HSA-5672591)
0.573
2
UniProt:O60269 GRIN2
0.573
2
UniProt:Q9Y2U5 M3K2
0.564
2
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.564
2
UniProt:Q13470 TNK1
0.564
2
UniProt:P30305 CDC25B
3
CDC25B [cytosol]
(R-HSA-157412)
p-S50,T69,S160,S321,S470-CDC25B [cytosol]
(R-HSA-8863644)
CDC25B [nucleoplasm]
(R-HSA-69734)
0.564
2
UniProt:P15056 BRAF
68
BRAF-MACF1fusion [cytosol]
(R-HSA-6802402)
p-S,T-BRAF [cytosol]
(R-HSA-169856)
p-BRAF-MACF1 fusion [cytosol]
(R-HSA-6802536)
BRAF [cytosol]
(R-HSA-167224)
BRAF E501G [cytosol]
(R-HSA-9651132)
BRAF D594N [cytosol]
(R-HSA-6802299)
BRAF D638E [cytosol]
(R-HSA-9651125)
BRAF G596R [cytosol]
(R-HSA-6802385)
BRAF D594V [cytosol]
(R-HSA-6802305)
BRAF G596V [cytosol]
(R-HSA-9651138)
BRAF G466E [cytosol]
(R-HSA-6802374)
BRAF D594G [cytosol]
(R-HSA-6802295)
BRAF L505H [cytosol]
(R-HSA-9648845)
BRAF F595L [cytosol]
(R-HSA-6802316)
BRAF L597V [cytosol]
(R-HSA-6802397)
BRAF G464E [cytosol]
(R-HSA-6802369)
BRAF N581D [cytosol]
(R-HSA-9651152)
BRAF E586K [cytosol]
(R-HSA-6802308)
BRAF V600K [cytosol]
(R-HSA-6802502)
BRAF A246P [cytosol]
(R-HSA-9651123)
BRAF G469V [cytosol]
(R-HSA-9648620)
BRAF T244P [cytosol]
(R-HSA-9651165)
BRAF G469R [cytosol]
(R-HSA-9648621)
BRAF L597R [cytosol]
(R-HSA-9648617)
BRAF G469E [cytosol]
(R-HSA-9648618)
BRAF L597Q [cytosol]
(R-HSA-9648619)
BRAF G466A [cytosol]
(R-HSA-9648613)
BRAF G466V [cytosol]
(R-HSA-9648838)
BRAF N581S [cytosol]
(R-HSA-9648850)
BRAF G464V [cytosol]
(R-HSA-9648611)
p-BRAF L597V [plasma membrane]
(R-HSA-8936647)
p-BRAF L505H [plasma membrane]
(R-HSA-9648862)
p-BRAF G464E [plasma membrane]
(R-HSA-8936645)
p-BRAF F595L [plasma membrane]
(R-HSA-8936641)
p-BRAF A246P [plasma membrane]
(R-HSA-9651188)
p-BRAF E586K [plasma membrane]
(R-HSA-8936639)
p-BRAF N581D [plasma membrane]
(R-HSA-9651191)
p-BRAF V600K [plasma membrane]
(R-HSA-8936651)
p-BRAF G464V [plasma membrane]
(R-HSA-9648633)
p-BRAF T244P [plasma membrane]
(R-HSA-9651194)
p-BRAF G469E [plasma membrane]
(R-HSA-9648634)
p-BRAF G466V [plasma membrane]
(R-HSA-9648859)
p-BRAF G469V [plasma membrane]
(R-HSA-9648628)
p-BRAF G466A [plasma membrane]
(R-HSA-9648629)
p-BRAF L597Q [plasma membrane]
(R-HSA-9648630)
p-BRAF L597R [plasma membrane]
(R-HSA-9648631)
p-BRAF N581S [plasma membrane]
(R-HSA-9648866)
p-BRAF G469R [plasma membrane]
(R-HSA-9648627)
BRAF 599dupT [cytosol]
(R-HSA-6802281)
BRAF G534R [cytosol]
(R-HSA-9651134)
BRAF S467A [cytosol]
(R-HSA-9651161)
BRAF K601N [cytosol]
(R-HSA-9648857)
BRAF G469A [cytosol]
(R-HSA-6802381)
BRAF L485F [cytosol]
(R-HSA-9651147)
BRAF Q257R [cytosol]
(R-HSA-9651157)
BRAF K499E [cytosol]
(R-HSA-9651142)
BRAF V600E [cytosol]
(R-HSA-6802498)
BRAF K601E [cytosol]
(R-HSA-9648833)
BRAF V600E V169_M438del [cytosol]
(R-HSA-6802489)
BRAF V600E V47_D380del [cytosol]
(R-HSA-6802491)
BRAF V600E V47_M438del [cytosol]
(R-HSA-6802495)
V600E BRAF V169_D380del [cytosol]
(R-HSA-6802486)
p-S445,S729-BRAF [plasma membrane]
(R-HSA-8933622)
hyperphosphorylated BRAF [plasma membrane]
(R-HSA-5675199)
p-S365,S445,S729 BRAF [cytosol]
(R-HSA-5672667)
p-S445,T599,S602,S729 BRAF [plasma membrane]
(R-HSA-5672679)
p-S445,S729-BRAF [cytosol]
(R-HSA-5672673)
p-S445,T599,S602,S729 BRAF [cytosol]
(R-HSA-5672676)
0.564
3
UniProt:P10636-2 MAPT
0.558
2
UniProt:Q13064 MKRN3
0.556
3
UniProt:Q86Z20 CC125
0.556
3
UniProt:Q9NYF3 FA53C
0.556
3
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.556
3
UniProt:Q17RB8 LONRF1
1
LONRF1 [cytosol]
(R-HSA-8850905)
0.556
3
UniProt:Q68D86 C102B
0.556
3
UniProt:Q8IZU0 FAM9B
0.556
3
UniProt:Q03373 DIG2
0.556
3
UniProt:Q53FD0 ZC21C
0.556
3
UniProt:P43355 MAGA1
0.556
3
UniProt:P55771 PAX9
0.556
3
UniProt:Q9UJM3 ERRFI
0.556
3
UniProt:P98177 FOXO4
8
p-T32,S197,S262-FOXO4 [nucleoplasm]
(R-HSA-199314)
FOXO4 [nucleoplasm]
(R-HSA-5690183)
p-T32,S197,S262-FOXO4 [cytosol]
(R-HSA-9614415)
SOH-C481-FOXO4 [nucleoplasm]
(R-HSA-9617655)
CREBBP-S-S-FOXO4 [nucleoplasm]
(R-HSA-9617679)
EP300-S-S-FOXO4 [nucleoplasm]
(R-HSA-9617681)
Ac-K-FOXO4 [nucleoplasm]
(R-HSA-9617761)
PolyUb-FOXO4 [nucleoplasm]
(R-HSA-6782501)
0.556
3
UniProt:Q9UQL6 HDAC5
1
HDAC5 [nucleoplasm]
(R-HSA-3004533)
0.547
3
UniProt:Q8NFH8-2 REPS2
0.544
2
UniProt:Q9UQC2 GAB2
4
p-Y452,Y476,Y584-GAB2 [cytosol]
(R-HSA-2685615)
p-Y-GAB2 [cytosol]
(R-HSA-912529)
GAB2 [cytosol]
(R-HSA-508239)
p-5Y-GAB2 [cytosol]
(R-HSA-8855574)
0.527
3
UniProt:Q96IF1 AJUBA
3
p-S-AJUBA [cytosol]
(R-HSA-2574841)
AJUBA [nucleoplasm]
(R-HSA-5687935)
AJUBA [cytosol]
(R-HSA-2564698)
0.524
2
UniProt:O00444 PLK4
1
PLK4 [cytosol]
(R-HSA-380286)
0.508
2
UniProt:P00519 ABL1
5
p-Y226,Y393-ABL1 [nucleoplasm]
(R-HSA-8985251)
ABL1 [cytosol]
(R-HSA-375987)
p-S456-ABL1 [nucleoplasm]
(R-HSA-5686576)
ABL1 [nucleoplasm]
(R-HSA-5686579)
p-Y226,Y393-ABL1 [cytosol]
(R-HSA-8942610)
0.499
2
UniProt:Q51451 Q51451
0.469
2
UniProt:P06493 CDK1
10
CDK1 [nucleoplasm]
(R-HSA-68889)
CDK1 [endoplasmic reticulum membrane]
(R-HSA-264424)
CDK1 [cytosol]
(R-HSA-170075)
p-T161-CDK1 [nucleoplasm]
(R-HSA-170066)
p-T161-CDK1 [cytosol]
(R-HSA-157415)
p-T14,Y15,T161-CDK1 [cytosol]
(R-HSA-170071)
p-T14-CDK1 [cytosol]
(R-HSA-170064)
p-T14-CDK1 [nucleoplasm]
(R-HSA-170045)
p-T14,Y15,T161-CDK1 [nucleoplasm]
(R-HSA-170074)
p-T14,T161-CDK1 [nucleoplasm]
(R-HSA-170078)
0.463
2
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