Reactome | YWHAQ [cytosol]

YWHAQ [cytosol]

Stable Identifier

R-HSA-1445116

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

14-3-3 theta, 14-3-3 protein theta, 1433T_HUMAN

Locations in the PathwayBrowser

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle Checkpoints (Homo sapiens)
  - G2/M Checkpoints (Homo sapiens)
    - G2/M DNA damage checkpoint (Homo sapiens)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Homo sapiens)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - SARS-CoV Infections (Homo sapiens)
    - SARS-CoV-2 Infection (Homo sapiens)
      - SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 targets host intracellular signalling and regulatory pathways (Homo sapiens)
        
        SARS-CoV-2 N binds to 14-3-3 proteins (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
        
        14-3-3 dimer:N [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)

Programmed Cell Death (Homo sapiens)

- Apoptosis (Homo sapiens)
  - Intrinsic Pathway for Apoptosis (Homo sapiens)
    - Activation of BH3-only proteins (Homo sapiens)
      - Activation of BAD and translocation to mitochondria (Homo sapiens)
        
        Activation of BAD by calcineurin (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
        
        Sequestration of BAD protein by 14-3-3 (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase Effectors (Homo sapiens)
      - RHO GTPases activate PKNs (Homo sapiens)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
    - 14-3-3 Binds p-S237-TBC1D1 (Homo sapiens)
      - 14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
      - p-S237-TBC1D1:14-3-3 [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
    - 14-3-3 binds p-5S,T642-AS160 (TBC1D4) (Homo sapiens)
      - 14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)
      - p-5S,T642-AS160:14-3-3:IRAP [cytoplasmic vesicle membrane] (Homo sapiens)
        
        Phospho AS160:14-3-3 [cytoplasmic vesicle membrane] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        YWHAQ dimer [cytosol] (Homo sapiens)
        
        YWHAQ [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P27348 YWHAQ

Gene Names

YWHAQ

Chain

chain:1-245

Reference Genes

BioGPS Gene:10971 YWHAQ

COSMIC (genes):YWHAQ YWHAQ

CTD Gene:10971 YWHAQ

dbSNP Gene:10971 YWHAQ

ENSEMBL:ENSG00000134308 YWHAQ

HGNC:12854 YWHAQ

KEGG Gene (Homo sapiens):10971 YWHAQ

Monarch:10971 YWHAQ

NCBI Gene:10971 YWHAQ

OMIM:609009 YWHAQ

UCSC:P27348 YWHAQ

Reference Transcript

RefSeq:NM_006826.3 YWHAQ

Other Identifiers

0000580112

10971

11715559_x_at

11758001_s_at

11758724_x_at

16894361

200693_PM_at

200693_at

212426_PM_s_at

212426_s_at

213699_PM_s_at

213699_s_at

2539870

2539871

2539872

2539873

2539874

2539878

2539880

2539883

2539899

2539900

2539901

2539903

32530_at

3308855

3947809

409_at

8050215

A_23_P131723

A_24_P199905

A_32_P202057

GE80214

GO:0003674

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005829

GO:0005925

GO:0006605

GO:0006810

GO:0007165

GO:0007264

GO:0008150

GO:0009058

GO:0015031

GO:0016020

GO:0019904

GO:0021762

GO:0032991

GO:0034613

GO:0034641

GO:0042802

GO:0043226

GO:0045892

GO:0047485

GO:0048856

GO:0070062

HMNXSV003017286

Hs.74405.2.A1_3p_a_at

ILMN_1674385

PH_hs_0031308

TC02001560.hg

X56468_at

g5803226_3p_a_at

Participates

as a component of

YWHAQ dimer [cytosol] (Homo sapiens)

Inferred To

Homologues of YWHAQ [cytosol] (Caenorhabditis elegans)

14-3-3zeta [cytosol] (Drosophila melanogaster)

par-5 [cytosol] (Caenorhabditis elegans)

ywhaqb [cytosol] (Danio rerio)

ywhaq [cytosol] (Xenopus tropicalis)

YWHAQ [cytosol] (Bos taurus)

YWHAQ [cytosol] (Caenorhabditis elegans)

YWHAQ [cytosol] (Canis familiaris)

YWHAQ [cytosol] (Gallus gallus)

YWHAQ [cytosol] (Sus scrofa)

14-3-3 theta [cytosol] (Mus musculus)

Ywhaq [cytosol] (Rattus norvegicus)

fttB [cytosol] (Dictyostelium discoideum)

ftt-2 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006817.1

OpenTargets

ENSG00000134308

GeneCards

P27348

HPA

ENSG00000134308-YWHAQ

Ensembl

ENST00000381844, ENST00000238081, ENSG00000134308, ENSP00000238081, ENSP00000371267

PRO

P27348

Pharos - Targets

P27348

PDB

5IQP, 6BQT, 2BTP, 6BCR, 6BD2, 6KZG, 6KZH

Interactors (35)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04049 RAF1	20	p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098) p-S621-RAF1 G361A [cytosol] (R-HSA-9656092) p-S621-RAF1 G370R [cytosol] (R-HSA-9656094)	0.886	8
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.862	10
UniProt:P15056 BRAF	20	BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620) BRAF T244P [cytosol] (R-HSA-9651165)	0.857	8
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.854	7
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.831	7
UniProt:P46937 YAP1	7	p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.823	6
UniProt:Q9UBF8 PI4KB	2	PI4KB [cytosol] (R-HSA-1604615) PI4KB [Golgi membrane] (R-HSA-1806202)	0.758	4
UniProt:P22681 CBL	20	CBL R420G [cytosol] (R-HSA-9706203) CBL R420Q [cytosol] (R-HSA-9706186) CBL Y371H [cytosol] (R-HSA-9706680) CBL H398Y [cytosol] (R-HSA-9706639) CBL P417A [cytosol] (R-HSA-9706636) CBL S376F [cytosol] (R-HSA-9706643) CBL del366-409 [cytosol] (R-HSA-9706179) CBL del366-477 [cytosol] (R-HSA-9706176) CBL R499L [cytosol] (R-HSA-9706678) CBL L380P [cytosol] (R-HSA-9706630) CBL L287R [cytosol] (R-HSA-9706693) CBL L380R [cytosol] (R-HSA-9706635) CBL G375P [cytosol] (R-HSA-9706219) CBL P417L [cytosol] (R-HSA-9706634) CBL H398Q [cytosol] (R-HSA-9706633) CBL P417R [cytosol] (R-HSA-9706632) CBL R499* [cytosol] (R-HSA-9706670) CBL H398R [cytosol] (R-HSA-9706638) CBL H398P [cytosol] (R-HSA-9706637) CBL G375fs*16 [cytosol] (R-HSA-9706211)	0.758	6
UniProt:P46527 CDKN1B	8	p-T187-CDKN1B [nucleoplasm] (R-HSA-187525) CDKN1B [nucleoplasm] (R-HSA-182563) p-Y88-CDKN1B [nucleoplasm] (R-HSA-8942808) p-Y88-CDKN1B [cytosol] (R-HSA-8848438) CDKN1B [cytosol] (R-HSA-198622) p-T157-CDKN1B [cytosol] (R-HSA-198629) p-S10 CDKN1B [nucleoplasm] (R-HSA-9632832) p-S10 CDKN1B [cytosol] (R-HSA-9632829)	0.724	5
UniProt:P49815 TSC2	4	p-S939,S1130,T1462-TSC2 [cytosol] (R-HSA-165164) p-S939,T1462-TSC2 [cytosol] (R-HSA-199484) TSC2 [cytosol] (R-HSA-2980548) p-S1387-TSC2 [cytosol] (R-HSA-3132769)	0.702	3
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.688	3
UniProt:P40818 USP8	2	p-T945-USP8 [cytosol] (R-HSA-1358714) USP8 [cytosol] (R-HSA-917720)	0.688	3
UniProt:Q92934 BAD	4	p-S99-BAD [cytosol] (R-HSA-198335) BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S128-BAD [cytosol] (R-HSA-217297)	0.687	5
UniProt:P26045 PTPN3	3	PTPN3 [plasma membrane] (R-HSA-5490317) p-S459 PTPN3 [cytosol] (R-HSA-8868111) PTPN3 [cytosol] (R-HSA-8867650)	0.671	4
UniProt:Q9UQC2 GAB2	5	p-Y-GAB2 [cytosol] (R-HSA-912529) GAB2 [cytosol] (R-HSA-508239) p-Y452,Y476,Y584-GAB2 [cytosol] (R-HSA-2685615) p-5Y-GAB2 [cytosol] (R-HSA-8855574) p-Y643-GAB2 [cytosol] (R-HSA-9677149)	0.643	4
UniProt:P56524 HDAC4	3	polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) HDAC4 [nucleoplasm] (R-HSA-351581)	0.643	3
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.643	5
UniProt:P23945 FSHR	1	FSHR [plasma membrane] (R-HSA-391380)	0.635	4
UniProt:Q6PKG0 LARP1	1	LARP1 [cytosol] (R-HSA-9760421)	0.589	2
UniProt:Q14678 KANK1	3	KANK1 [nucleoplasm] (R-HSA-9018640) p-12Y KANK1(1-899)-PDGFRB(415-1106) fusion [plasma membrane] (R-HSA-9673890) KANK1(1-899)-PDGFRB(415-1106) fusion [plasma membrane] (R-HSA-9673593)	0.589	2
UniProt:P30304 CDC25A	6	CDC25A [nucleoplasm] (R-HSA-143487) CDC25A [cytosol] (R-HSA-157410) p-S123-CDC25A [nucleoplasm] (R-HSA-143488) p-S123-CDC25A [cytosol] (R-HSA-69588) p-S40,S116,S261-CDC25A [nucleoplasm] (R-HSA-8863634) PolyUb-CDC25A [cytosol] (R-HSA-6782810)	0.569	3
UniProt:Q9P0V3 SH3BP4	1	SH3BP4 [cytosol] (R-HSA-8866227)	0.564	2
UniProt:Q9BZ23 PANK2	1	PANK2(111-570) [mitochondrial intermembrane space] (R-HSA-196803)	0.564	2
UniProt:Q02241 KIF23	3	KIF23 [nucleoplasm] (R-HSA-156709) p-S904,S905-KIF23 [nucleoplasm] (R-HSA-156695) KIF23 [cytosol] (R-HSA-1015863)	0.564	2
UniProt:Q9Y4H2 IRS2	4	IRS2 [plasma membrane] (R-HSA-2428927) IRS2 [cytosol] (R-HSA-57528) p-Y-IRS2 [cytosol] (R-HSA-74774) p-Y-IRS2 [plasma membrane] (R-HSA-198334)	0.564	2
UniProt:P10636 MAPT	3	MAPT(422-758) [cytosol] (R-HSA-350642) MAPT(2-421) [cytosol] (R-HSA-350628) MAPT [cytosol] (R-HSA-201574)	0.547	2
UniProt:O15530 PDPK1	2	PDPK1 [cytosol] (R-HSA-202210) PDPK1 [plasma membrane] (R-HSA-61459)	0.544	3
UniProt:Q02750 MAP2K1	20	MAP2K1(9-393) [cytosol] (R-HSA-5211353) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1 F53S [cytosol] (R-HSA-9652034) MAP2K1 D67N [cytosol] (R-HSA-9652016) MAP2K1 Q56P [cytosol] (R-HSA-9652064) MAP2K1 E203K [cytosol] (R-HSA-9652023) MAP2K1 V60E [cytosol] (R-HSA-9652067) MAP2K1 P124S [cytosol] (R-HSA-9652062) MAP2K1 Y130C [cytosol] (R-HSA-9652101) MAP2K1 C121S [cytosol] (R-HSA-9652013) MAP2K1 G128V [cytosol] (R-HSA-9652047) MAP2K1 F53L [cytosol] (R-HSA-9652031) MAP2K1 K57N [cytosol] (R-HSA-9652050) MAP2K1 K57T [cytosol] (R-HSA-9652052) MAP2K1 F53V [cytosol] (R-HSA-9652038) MAP2K1 D67Y [cytosol] (R-HSA-9652019) MAP2K1 G128D [cytosol] (R-HSA-9652043) MAP2K1 P124L [cytosol] (R-HSA-9652056) MAP2K1 F53Y [cytosol] (R-HSA-9652041) MAP2K1 E44_E57del [cytosol] (R-HSA-9652026)	0.527	3
UniProt:P30305 CDC25B	3	p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644) CDC25B [cytosol] (R-HSA-157412) CDC25B [nucleoplasm] (R-HSA-69734)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.527	10
UniProt:P29074 PTPN4	2	PTPN4 [nucleoplasm] (R-HSA-9008925) PTPN4 [cytosol] (R-HSA-8877173)	0.527	2
UniProt:P36507 MAP2K2	12	MAP2K2(1-10) [cytosol] (R-HSA-5211334) MAP2K2(11-400) [cytosol] (R-HSA-5211337) MAP2K2 C125S [cytosol] (R-HSA-9652070) MAP2K2 P128Q [cytosol] (R-HSA-9652082) MAP2K2 V35M [cytosol] (R-HSA-9652086) MAP2K2 Y134C [cytosol] (R-HSA-9652089) p-S222,S226-MAP2K2 [cytosol] (R-HSA-169292) MAP2K2 [cytosol] (R-HSA-59504) p-S,T-MAP2K2 [cytosol] (R-HSA-109848) MAP2K2 N126D [cytosol] (R-HSA-9652079) MAP2K2 L46F [cytosol] (R-HSA-9652076) MAP2K2 F57C [cytosol] (R-HSA-9652073)	0.527	3
UniProt:P32121 ARRB2	2	ARRB2 [cytosol] (R-HSA-416464) PolyUb-ARRB2 [cytosol] (R-HSA-6783000)	0.499	3
UniProt:P49407 ARRB1	5	ARRB1 [cytosol] (R-HSA-264470) PolyUb-ARRB1 [cytosol] (R-HSA-6783186) ARRB1 [lysosomal membrane] (R-HSA-432701) ARRB1 [Golgi membrane] (R-HSA-350831) ARRB1 [cytoplasmic vesicle membrane] (R-HSA-351187)	0.499	3
UniProt:Q6PJG9 LRFN4	1	SALM3 [plasma membrane] (R-HSA-197883)	0.462	3

Cite Us!