p-AKT2 phosphorylates RGC2

Stable Identifier
R-HSA-1458463
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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As inferred from mouse, AKT2 (PKB-beta) phosphorylates RBC2 (RALGAPA2) on serine-486, serine-696, and threonine-715 in response to insulin. The phosphorylation prevents RBC1:RBC2 from activating RALA GTPase and allows RALA:GTP to accumulate.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-T309,S474-AKT2 [plasma membrane]
Physical Entity
Activity
Inferred From
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Reviewed
Created