Collagen type II degradation by MMP14

Stable Identifier
R-HSA-1474196
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The membrane-type MMP MMP14 (MT1-MMP) is a fibrillar collagenase. MMP14 is able to degrade collagen types I, II and III (Ohuchi et al. 1997).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
metalloendopeptidase activity of MMP14,TMPRSS6 [plasma membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created