Synthesis of PI

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R-HSA-1483226
Type
Pathway
Species
Homo sapiens
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Phosphatidylinositol (PI) is synthesized when phosphatidic acid (PA) and cytidine triphosphate (CTP) are converted into cytidine diphosphate-diacylglycerol (CDP-DAG) followed by conversion into PI and cytidine monophosphate (CMP) (Stuhne-Sekalec et al 1986, Lykidis et al. 1997).

Literature References
PubMed ID Title Journal Year
3718705 Participation of the microsomal CDP-diglycerides in the mitochondrial biosynthesis of phosphatidylglycerol

Stuhne-Sekalec, L, Chudzik, J, Stanacev, NZ

Biochem Cell Biol 1986
9407135 The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content

Lykidis, A, Jackson, PD, Rock, CO, Jackowski, S

J Biol Chem 1997
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