Synthesis of PIPs at the ER membrane

Stable Identifier
R-HSA-1483248
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

At the endoplasmic reticulum (ER) membrane, phosphatidylinositol (PI) and phosphatidylinositol 4-phosphate (PI4P) are interconverted (Wong et al. 1997, Gehrmann et al. 1999, Wei et al. 2002, Rohde et al. 2003).

Literature References
PubMed ID Title Journal Year
9148941 Subcellular locations of phosphatidylinositol 4-kinase isoforms

Wong, K, Meyers, ddR, Cantley, LC

J Biol Chem 1997
12324459 Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP

Wei, YJ, Sun, HQ, Yamamoto, M, Wlodarski, P, Kunii, K, Martínez, M, Barylko, B, Albanesi, JP, Yin, HL

J Biol Chem 2002
10101268 Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230

Gehrmann, T, Gülkan, H, Suer, S, Herberg, FW, Balla, A, Vereb, G, Mayr, GW, Heilmeyer LM, Jr

Biochim Biophys Acta 1999
14527956 The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex

Rohde, HM, Cheong, FY, Konrad, G, Paiha, K, Mayinger, P, Boehmelt, G

J Biol Chem 2003
Participants
Participant Of
hasEvent
Event Information
Orthologous Events
Cross References
BioModels Database
Authored
Reviewed