Reactome | CDIPT [endoplasmic reticulum membrane]

CDIPT [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1498749

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

CDP-diacylglycerol--inositol 3-phosphatidyltransferase, Phosphatidylinositol synthase, PI synthase, PtdIns synthase

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O14735 CDIPT

Gene Names

CDIPT, PIS, PIS1

Chain

chain:1-213

Reference Genes

BioGPS Gene:10423 CDIPT

COSMIC (genes):CDIPT CDIPT

CTD Gene:10423 CDIPT

dbSNP Gene:10423 CDIPT

ENSEMBL:ENSG00000103502 CDIPT

HGNC:1769 CDIPT

KEGG:hsa:10423 CDIPT

Monarch:10423 CDIPT

NCBI Gene:10423 CDIPT

OMIM:605893 CDIPT

UCSC:O14735 CDIPT

Reference Transcript

Other Identifiers

10423

11715862_x_at

11746473_x_at

11754080_x_at

16825548

201253_PM_s_at

201253_s_at

33397_at

3687261

3687262

3687263

3687264

3687265

3687266

3687267

3687268

3687269

3687270

3687271

3687272

3687273

3687274

3687275

3687276

58821_at

8000706

A_23_P501339

GE79539

GO:0003824

GO:0003881

GO:0005515

GO:0005783

GO:0005789

GO:0005794

GO:0005886

GO:0006629

GO:0006661

GO:0008654

GO:0016020

GO:0016740

GO:0016780

GO:0043226

GO:0046872

HMNXSV003033930

ILMN_1737003

ILMN_1770425

PH_hs_0027227

TC16001011.hg

g5453905_3p_a_at

Participates

as a component of

CDIPT:Mg2+/Mn2+ [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

pisy-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

CDIPT [endoplasmic reticulum membrane] (Bos taurus)

CDIPT [endoplasmic reticulum membrane] (Canis familiaris)

CDIPT [endoplasmic reticulum membrane] (Dictyostelium discoideum)

CDIPT [endoplasmic reticulum membrane] (Drosophila melanogaster)

CDIPT [endoplasmic reticulum membrane] (Mus musculus)

CDIPT [endoplasmic reticulum membrane] (Plasmodium falciparum)

CDIPT [endoplasmic reticulum membrane] (Rattus norvegicus)

CDIPT [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

CDIPT [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

CDIPT [endoplasmic reticulum membrane] (Sus scrofa)

cdipt [endoplasmic reticulum membrane] (Danio rerio)

cdipt [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_006310.1, NP_001273514.1

ENSEMBL

ENSP00000454453, ENST00000219789, ENSP00000457339, ENST00000569956, ENST00000570016, ENSG00000103502, ENST00000566113, ENSP00000457340, ENSP00000219789

OpenTargets

ENSG00000103502

GeneCards

CDIPT

HPA

ENSG00000103502-CDIPT

PRO

O14735

Pharos - Targets

O14735

HMDB Protein

HMDBP00771

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:P24592 IGFBP6	1	IGFBP6 [extracellular region] (R-HSA-381475)	0.556	3
UniProt:P08034 GJB1	2	GJB1 [endoplasmic reticulum membrane] (R-HSA-190656) GJB1 [endoplasmic reticulum-Golgi intermediate compartment] (R-HSA-190636)	0.556	3
UniProt:O15342 ATP6V0E1	3	ATP6V0E1 [endosome membrane] (R-HSA-912582) ATP6V0E1 [phagocytic vesicle membrane] (R-HSA-1222533) ATP6V0E1 [lysosomal membrane] (R-HSA-9640180)	0.556	3
UniProt:Q8N9R8 SCAI	1	SCAI [nucleoplasm] (R-HSA-5666012)	0.556	3
UniProt:Q7Z5P4 HSD17B13	1	HSD17B13 [cytosol] (R-HSA-8862029)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.556	3
UniProt:O95197 RTN3	1	RTN3 [plasma membrane] (R-HSA-8849907)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:Q8N0Z6 TTC5	3	p-S203,S221-TTC5 [nucleoplasm] (R-HSA-6804259) p-S203-TTC5 [nucleoplasm] (R-HSA-6804261) TTC5 [nucleoplasm] (R-HSA-6804264)	0.527	2
UniProt:Q9BVC3 DSCC1	1	DSCC1 [nucleoplasm] (R-HSA-9668907)	0.527	2

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