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CDS2 [mitochondrial inner membrane]
Stable Identifier
R-HSA-1498755
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Phosphatidate cytidylyltransferase 2, CDP-DAG synthase 2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Synthesis of PG (Homo sapiens)
PA is converted to CDP-DAG by CDS2 (Homo sapiens)
CDS2 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O95674 CDS2
Gene Names
CDS2
Chain
chain:1-445
Reference Genes
BioGPS Gene:8760 CDS2
COSMIC (genes):CDS2 CDS2
CTD Gene:8760 CDS2
dbSNP Gene:8760 CDS2
ENSEMBL:ENSG00000101290 CDS2
ENSEMBL_homo_sapiens_GENE:ENSG00000101290.14 CDS2
HGNC:1801 CDS2
KEGG Gene (Homo sapiens):8760 CDS2
Monarch:8760 CDS2
NCBI Gene:8760 CDS2
OMIM:603549 CDS2
UCSC:O95674 CDS2
Reference Transcript
RefSeq:NM_003818.3 CDS2
Other Identifiers
11721283_a_at
11721284_a_at
16911151
212862_PM_at
212862_at
212864_PM_at
212864_at
228456_PM_s_at
228456_s_at
228861_PM_at
228861_at
233630_3p_at
233630_PM_at
233630_at
3874901
3874902
3874903
3874913
3874914
3874917
3874921
3874922
3874925
3874926
3874927
3874929
3874931
3874932
3874934
3874935
3874936
3874937
3874938
3874939
3874940
3874941
3874942
3874944
3874946
3874948
3874949
3874951
41343_at
64148_at
76836_at
8060772
8760
A_14_P132817
A_23_P154698
A_24_P271363
GE60331
GE744004
GE849129
GO:0003824
GO:0004605
GO:0005515
GO:0005739
GO:0005743
GO:0005783
GO:0005789
GO:0006629
GO:0006655
GO:0008654
GO:0016020
GO:0016024
GO:0016740
GO:0016772
GO:0016779
GO:0043226
GO:0140042
HMNXSV003026077
Hs.126857.1.A1_3p_at
Hs.135040.0.A1_3p_at
Hs.24812.0.S1_3p_at
Hs.24812.0.S2_3p_at
Hs.306912.0.S1_3p_x_at
ILMN_1790973
PH_hs_0007239
PH_hs_0023667
TC20000056.hg
TC20001076.hg
Inferred To
Cds [mitochondrial inner membrane]
(Drosophila melanogaster)
cdsA [mitochondrial inner membrane]
(Dictyostelium discoideum)
CDS1 [mitochondrial inner membrane]
(Saccharomyces cerevisiae)
CDS2 [mitochondrial inner membrane]
(Bos taurus)
CDS2 [mitochondrial inner membrane]
(Canis familiaris)
CDS2 [mitochondrial inner membrane]
(Gallus gallus)
CDS2 [mitochondrial inner membrane]
(Plasmodium falciparum)
CDS2 [mitochondrial inner membrane]
(Schizosaccharomyces pombe)
CDS2 [mitochondrial inner membrane]
(Sus scrofa)
Cds2 [mitochondrial inner membrane]
(Mus musculus)
Cds2 [mitochondrial inner membrane]
(Rattus norvegicus)
cdgs-1 [mitochondrial inner membrane]
(Caenorhabditis elegans)
cds2 [mitochondrial inner membrane]
(Danio rerio)
cds2 [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_003809.1
OpenTargets
ENSG00000101290
IntEnz
2.7.7.41
GeneCards
O95674
HPA
ENSG00000101290-CDS2
Ensembl
ENSP00000403205
,
ENST00000450570
,
ENSP00000419879
,
ENST00000460006
,
ENSG00000101290
PRO
O95674
Pharos - Targets
O95674
HMDB Protein
HMDBP00746
Interactors (39)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P22607 FGFR3
20
FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane]
(R-HSA-8853144)
FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane]
(R-HSA-8853131)
FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane]
(R-HSA-8853152)
FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane]
(R-HSA-8853124)
FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane]
(R-HSA-8853125)
FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]
(R-HSA-8853127)
FGFR3 K650T [plasma membrane]
(R-HSA-1614411)
FGFR3 K650N [plasma membrane]
(R-HSA-1614406)
FGFR3 K650M [plasma membrane]
(R-HSA-1614402)
FGFR3 K650Q [plasma membrane]
(R-HSA-1614410)
FGFR3 A391E [plasma membrane]
(R-HSA-1614390)
FGFR3 K650E [plasma membrane]
(R-HSA-1614400)
FGFR3 G380R [plasma membrane]
(R-HSA-1614398)
FGFR3 G382D [plasma membrane]
(R-HSA-2018740)
FGFR3 805fs*141 [plasma membrane]
(R-HSA-1614387)
FGFR3 [plasma membrane]
(R-HSA-2038357)
FGFR3 S371C [plasma membrane]
(R-HSA-1614421)
FGFR3 Y373C [plasma membrane]
(R-HSA-1614424)
FGFR3 G370C [plasma membrane]
(R-HSA-1614394)
FGFR3 R248C [plasma membrane]
(R-HSA-1614419)
0.659
4
UniProt:Q7Z699 SPRED1
2
SPRED1 [plasma membrane]
(R-HSA-5658225)
SPRED1 [cytosol]
(R-HSA-5654207)
0.556
3
UniProt:O75400-2 PRPF40A
0.556
3
UniProt:Q9H9V4 RN122
0.556
3
UniProt:Q9Y649 Q9Y649
0.556
3
UniProt:Q8IV31 TM139
0.556
3
UniProt:Q8TDT2 GP152
0.556
3
UniProt:P62826 RAN
2
RAN [nucleoplasm]
(R-HSA-165528)
RAN [cytosol]
(R-HSA-165540)
0.556
3
UniProt:Q9HB07 MYG1
0.556
3
UniProt:Q8WWF3 SSMM1
0.556
3
UniProt:Q96B21 TM45B
0.556
3
UniProt:P13473-2 P134732
0.556
3
UniProt:Q9Y320 TMX2
0.556
3
UniProt:Q95460-2 MR1
0.556
3
UniProt:Q96MG2 JSPR1
0.556
3
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:Q9NPL8 TIMMDC1
1
TIMMDC1 [mitochondrial inner membrane]
(R-HSA-5689720)
0.556
3
UniProt:Q9Y282 ERGI3
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
UniProt:A8MZ59 LEUTX
1
LEUTX [nucleoplasm]
(R-HSA-9817277)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
9
UniProt:Q13651 IL10RA
3
p-Y446-IL10RA [plasma membrane]
(R-HSA-6784810)
p-Y496-IL10RA [plasma membrane]
(R-HSA-6784793)
IL10RA [plasma membrane]
(R-HSA-449841)
0.556
3
UniProt:P31948 STIP1
1
STIP1 [cytosol]
(R-HSA-443857)
0.556
3
UniProt:P55212 CASP6
5
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(194-293) [cytosol]
(R-HSA-266128)
0.556
3
UniProt:P06396 GSN
7
GSN(200-270) [extracellular region]
(R-HSA-976940)
GSN [secretory granule lumen]
(R-HSA-6801486)
GSN [extracellular region]
(R-HSA-6806510)
GSN [ficolin-1-rich granule lumen]
(R-HSA-6801465)
GSN(404-782) [cytosol]
(R-HSA-350272)
GSN(28-403) [cytosol]
(R-HSA-201618)
GSN [cytosol]
(R-HSA-350275)
0.556
3
UniProt:Q92870-2 Q928702
0.556
3
IntAct:EBI-25847655 CCSB
0.556
3
UniProt:O95859 TSN12
0.556
3
UniProt:P28329-3 P283293
0.556
3
UniProt:P31937 HIBADH
1
HIBADH [mitochondrial matrix]
(R-HSA-70882)
0.556
3
UniProt:Q86WV8 Q86WV8
0.556
3
UniProt:P01112 HRAS
20
HRAS Q61R [plasma membrane]
(R-HSA-6802458)
HRAS Q61L [plasma membrane]
(R-HSA-6802452)
HRAS Q61K [plasma membrane]
(R-HSA-6802442)
HRAS G13R [plasma membrane]
(R-HSA-6802368)
HRAS G12V [plasma membrane]
(R-HSA-6802350)
HRAS G12S [plasma membrane]
(R-HSA-6802343)
HRAS T58I [plasma membrane]
(R-HSA-9656014)
HRAS G13C [plasma membrane]
(R-HSA-9656008)
HRAS K117R [plasma membrane]
(R-HSA-9656010)
HRAS G13V [plasma membrane]
(R-HSA-9656579)
HRAS G13D [plasma membrane]
(R-HSA-9656572)
HRAS G13S [plasma membrane]
(R-HSA-9656574)
HRAS K117N [plasma membrane]
(R-HSA-9656603)
HRAS G12D [plasma membrane]
(R-HSA-9656564)
HRAS G12C [plasma membrane]
(R-HSA-9656561)
HRAS [plasma membrane]
(R-HSA-62717)
S-Farn-Me HRAS [plasma membrane]
(R-HSA-9665052)
S-Farn-Me PalmS HRAS [Golgi membrane]
(R-HSA-9647896)
S-Farn-Me HRAS [endoplasmic reticulum membrane]
(R-HSA-9647796)
S-Farn-HRAS [endoplasmic reticulum membrane]
(R-HSA-9647788)
0.556
3
UniProt:Q14957 GRIN2C
3
GRIN2C [plasma membrane]
(R-HSA-419560)
p-Y-GRIN2C [plasma membrane]
(R-HSA-9612189)
GRIN2C [endoplasmic reticulum membrane]
(R-HSA-9609761)
0.556
3
UniProt:G5E9A7 G5E9A7
0.556
3
UniProt:Q5JX71 F209A
0.556
3
UniProt:Q7Z7G2 CPLX4
0.556
3
UniProt:Q9H2K0 MTIF3
1
MTIF3 [mitochondrial matrix]
(R-HSA-5368284)
0.556
3
UniProt:Q8TAF8 LHFPL5
1
LHFPL5 [plasma membrane]
(R-HSA-9658860)
0.556
3
UniProt:Q92903 CDS1
1
CDS1 [endoplasmic reticulum membrane]
(R-HSA-1498762)
0.527
4
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