Reactome | KIF23 [nucleoplasm]

KIF23 [nucleoplasm]

Stable Identifier

R-HSA-156709

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

MKLP1, Kinesin-like protein KIF23

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q02241 KIF23

Gene Names

KIF23, KNSL5, MKLP1

Chain

chain:1-960

Reference Genes

BioGPS Gene:9493 KIF23

COSMIC (genes):KIF23 KIF23

CTD Gene:9493 KIF23

dbSNP Gene:9493 KIF23

ENSEMBL:ENSG00000137807 KIF23

HGNC:6392 KIF23

KEGG Gene (Homo sapiens):9493 KIF23

Monarch:9493 KIF23

NCBI Gene:9493 KIF23

OMIM:605064 KIF23

UCSC:Q02241 KIF23

Reference Transcript

Other Identifiers

0003520017

0004070706

11721932_a_at

11756918_a_at

16802519

204709_s_at

3599812

3599813

3599815

3599816

3599817

3599818

3599820

3599823

3599825

3599826

3599828

3599829

3599830

3599831

3599832

3599833

3599836

3599837

3599838

3599839

3599843

3599845

3599848

3599851

3599852

3599853

37171_at

7984540

9493

A_14_P119304

A_14_P128503

A_23_P48835

A_33_P3311755

GE62342

GO:0000022

GO:0000166

GO:0000278

GO:0000281

GO:0000915

GO:0002376

GO:0003674

GO:0003777

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0005871

GO:0005874

GO:0005925

GO:0006810

GO:0006890

GO:0007010

GO:0007018

GO:0007049

GO:0007059

GO:0008017

GO:0008092

GO:0008150

GO:0016192

GO:0016887

GO:0019886

GO:0022607

GO:0030496

GO:0030705

GO:0032467

GO:0032991

GO:0043167

GO:0043226

GO:0045171

GO:0051256

GO:0051276

GO:0051301

GO:0072383

GO:0072686

GO:0090543

GO:0097149

GO:0140014

ILMN_1716553

ILMN_1811472

PH_hs_0013935

TC15000638.hg

X67155_at

g13699831_3p_a_at

Participant Of

input

Regulation of KIF23 (MKLP1) by phosphorylation

Other forms of this molecule

p-S904,S905-KIF23 [nucleoplasm]

KIF23 [cytosol]

Inferred To

Kif23 [nucleoplasm] (Mus musculus)

Kif23 [nucleoplasm] (Rattus norvegicus)

zen-4 [nucleoplasm] (Caenorhabditis elegans)

pav [nucleoplasm] (Drosophila melanogaster)

kif23 [nucleoplasm] (Danio rerio)

kif23 [nucleoplasm] (Xenopus tropicalis)

klp9 [nucleoplasm] (Schizosaccharomyces pombe)

kif12 [nucleoplasm] (Dictyostelium discoideum)

KIF23 [nucleoplasm] (Canis familiaris)

KIF23 [nucleoplasm] (Gallus gallus)

KIF23 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_004847.2, NP_612565.1

OpenTargets

ENSG00000137807

GeneCards

Q02241

HPA

ENSG00000137807-KIF23

ZINC target

Q02241

Ensembl

ENST00000647715, ENSP00000260363, ENSP00000304978, ENST00000260363, ENSG00000137807, ENSP00000497065, ENST00000352331

PRO

Q02241

Orphanet

22229

PDB

3VHX

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.836	6
UniProt:Q9H0H5 RACGAP1	1	RACGAP1 [cytosol] (R-HSA-195122)	0.816	12
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.813	5
UniProt:Q04917 YWHAH	1	YWHAH [cytosol] (R-HSA-1445107)	0.725	4
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.688	3
UniProt:P62330 ARF6	2	ARF6 [recycling endosome membrane] (R-HSA-2029049) ARF6 [cytosol] (R-HSA-8871121)	0.667	23
UniProt:P62331	2	Arf6 [recycling endosome membrane] (R-MMU-2029049) Arf6 [cytosol] (R-MMU-8871121)	0.66	10
UniProt:Q7RTP6-1 MICAL3			0.576	8
UniProt:Q9H8V3 ECT2	1	ECT2 [cytosol] (R-HSA-195036)	0.564	2
UniProt:Q9WVM1	1	Racgap1 [cytosol] (R-MMU-195122)	0.564	2
UniProt:Q9JLQ0 Cd2ap	1	CD2AP_MOUSE [cytosol] (R-MMU-451711)	0.564	2
UniProt:Q9Z179 SHCBP			0.564	2
UniProt:P27348 YWHAQ	1	YWHAQ [cytosol] (R-HSA-1445116)	0.564	2
UniProt:Q9NR09 BIRC6			0.556	4
UniProt:Q7RTP6 MICA3			0.491	2
UniProt:Q96NL6 SCLT1	1	SCLT1 [cytosol] (R-HSA-5620935)	0.462	2

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