Reactome | NUDC [nucleoplasm]

NUDC [nucleoplasm]

Stable Identifier

R-HSA-156716

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:P32780 GTF2H1

Expand all

External Reference Information

External Reference

UniProt:Q9Y266 NUDC

Gene Names

NUDC

Chain

chain:1-331

Reference Genes

BioGPS Gene:10726 NUDC

COSMIC (genes):NUDC NUDC

CTD Gene:10726 NUDC

dbSNP Gene:10726 NUDC

ENSEMBL:ENSG00000090273 NUDC

ENSEMBL_homo_sapiens_GENE:ENSG00000090273.14 NUDC

HGNC:8045 NUDC

KEGG Gene (Homo sapiens):10726 NUDC

Monarch:10726 NUDC

NCBI Gene:10726 NUDC

OMIM:610325 NUDC

UCSC:Q9Y266 NUDC

Reference Transcript

RefSeq:NM_006600.3 NUDC

Other Identifiers

10726

11716166_x_at

16661323

201173_PM_x_at

201173_x_at

210574_PM_s_at

210574_s_at

2326805

2326806

2326808

2326812

2326813

2326814

2326815

2326817

2326818

2326822

2326824

2326827

2326828

2326829

2510739

2510740

2510743

2517704

2517706

2517709

2517710

2517713

35836_at

7899273

A_23_P74653

GE79197

GO:0000278

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005819

GO:0005829

GO:0005856

GO:0005874

GO:0006457

GO:0007010

GO:0007049

GO:0007052

GO:0007059

GO:0007080

GO:0007097

GO:0030496

GO:0043226

GO:0043434

GO:0045296

GO:0051082

GO:0051301

GO:0072686

GO:0140014

HMNXSV003014386

ILMN_2097546

PH_hs_0029543

TC01000355.hg

g12005492_3p_s_at

Participates

as an input of

PLK1 phosphorylates NUDC (Homo sapiens)

Other forms of this molecule

NUDC [cytosol]

p-S274,S326-NUDC [cytosol]

p-S274,S326-NUDC [spindle]

Inferred To

NUDC [nucleoplasm] (Bos taurus)

NUDC [nucleoplasm] (Canis familiaris)

NUDC [nucleoplasm] (Gallus gallus)

NUDC [nucleoplasm] (Plasmodium falciparum)

NUDC [nucleoplasm] (Sus scrofa)

nud-1 [nucleoplasm] (Caenorhabditis elegans)

nudc [nucleoplasm] (Danio rerio)

nudc [nucleoplasm] (Dictyostelium discoideum)

nudc [nucleoplasm] (Schizosaccharomyces pombe)

nudc [nucleoplasm] (Xenopus tropicalis)

Nudc [nucleoplasm] (Mus musculus)

Nudc [nucleoplasm] (Rattus norvegicus)

nudC [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_006591.1

OpenTargets

ENSG00000090273

HPA

ENSG00000090273-NUDC

GeneCards

Q9Y266

Ensembl

ENSG00000090273, ENST00000321265, ENSP00000319664

PRO

Q9Y266

Pharos - Targets

Q9Y266

PDB

7NDX, 3QOR

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TC44 POC1B			0.731	5
UniProt:Q8WVS4 DYNC2I1	2	WDR60 [ciliary tip] (R-HSA-5625409) WDR60 [cilium] (R-HSA-5624903)	0.657	4
UniProt:Q8NBT0 POC1A			0.65	3
UniProt:P25685 DNAJB1	3	p-S149,S151,S171 DNAJB1 [cytosol] (R-HSA-5690241) DNAJB1 [cytosol] (R-HSA-3299666) DNAJB1 [nucleoplasm] (R-HSA-5082366)	0.638	3
UniProt:O60884 DNAJA2	1	DNAJA2 [cytosol] (R-HSA-3371555)	0.623	4
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.569	8
UniProt:Q9P2S5 WRP73			0.564	2
UniProt:O00423 EMAL1			0.564	2
UniProt:Q96P53 WDFY2			0.564	2
UniProt:P02489 CRYAA			0.556	3
UniProt:Q86V38 Q86V38			0.556	3
UniProt:O14908-2 GIPC1			0.556	3
UniProt:Q9UKB1 FBXW11	1	FBXW11 [cytosol] (R-HSA-976035)	0.527	3
UniProt:Q9Y297 BTRC	2	BTRC [cytosol] (R-HSA-174237) BTRC [nucleoplasm] (R-HSA-3361753)	0.527	3
UniProt:P31689 DNAJA1	2	SOH-C149,C150-DNAJA1 [cytosol] (R-HSA-9857072) DNAJA1 [cytosol] (R-HSA-3371544)	0.527	2
UniProt:Q13451 FKBP5	2	FKBP5 [cytosol] (R-HSA-5618096) FKBP5 [nucleoplasm] (R-HSA-8939165)	0.527	2
UniProt:Q92918 M4K1			0.527	3
UniProt:Q9P2H3 IFT80	2	IFT80 [cilium] (R-HSA-5617613) IFT80 [ciliary tip] (R-HSA-5625367)	0.508	3
UniProt:Q9UG01 IFT172	2	IFT172 [ciliary tip] (R-HSA-5625353) IFT172 [cilium] (R-HSA-5610383)	0.508	2
UniProt:Q9UDY4 DNJB4			0.508	2
UniProt:P32780 GTF2H1	1	GTF2H1 [nucleoplasm] (R-HSA-65912)	0.508	2
UniProt:Q9UKT8 FBXW2	1	FBXW2 [cytosol] (R-HSA-391300)	0.499	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	11
UniProt:Q9Y4P8 WIPI2	1	WIPI2 [cytosol] (R-HSA-5678305)	0.483	4
UniProt:P03366 POL			0.462	2

Cite Us!