Reactome | UPF3B [nucleoplasm]

UPF3B [nucleoplasm]

Stable Identifier

R-HSA-156776

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

hUpf3B, UPf3B

Locations in the PathwayBrowser for interactor UniProt:O15234 CASC3

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External Reference Information

External Reference

UniProt:Q9BZI7 UPF3B

Gene Names

UPF3B, RENT3B, UPF3X

Chain

chain:1-483

Reference Genes

BioGPS Gene:65109 UPF3B

COSMIC (genes):UPF3B UPF3B

CTD Gene:65109 UPF3B

dbSNP Gene:65109 UPF3B

ENSEMBL:ENSG00000125351 UPF3B

HGNC:20439 UPF3B

KEGG:hsa:65109 UPF3B

Monarch:65109 UPF3B

NCBI Gene:65109 UPF3B

OMIM:300298 UPF3B

UCSC:Q9BZI7 UPF3B

Reference Transcript

Participates

as an input of

Formation of the Spliceosomal B* complex (Homo sapiens)

as a component of

Other forms of this molecule

UPF3B [cytosol]

Inferred To

Upf3 [nucleoplasm] (Drosophila melanogaster)

Upf3b [nucleoplasm] (Mus musculus)

Upf3b [nucleoplasm] (Rattus norvegicus)

Ghost homologue of UPF3B [nucleoplasm] (Bos taurus)

Ghost homologue of UPF3B [nucleoplasm] (Canis familiaris)

Ghost homologue of UPF3B [nucleoplasm] (Plasmodium falciparum)

upf3 [nucleoplasm] (Schizosaccharomyces pombe)

smg-4 [nucleoplasm] (Caenorhabditis elegans)

upf3b [nucleoplasm] (Danio rerio)

upf3b [nucleoplasm] (Xenopus tropicalis)

UPF3B [nucleoplasm] (Dictyostelium discoideum)

UPF3B [nucleoplasm] (Gallus gallus)

UPF3B [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_075386.1, NP_542199.1

ENSEMBL

ENSP00000245418, ENSP00000276201, ENST00000345865, ENSG00000125351, ENST00000276201

OpenTargets

ENSG00000125351

GeneCards

UPF3B

HPA

ENSG00000125351-UPF3B

PRO

Q9BZI7

Pharos - Targets

Q9BZI7

GlyGen

Q9BZI7

Orphanet

UPF3B

PDB

7NWU, 1UW4, 2XB2

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y5S9 RBM8A	2	RBM8A [nucleoplasm] (R-HSA-156659) RBM8A [cytosol] (R-HSA-162462)	0.914	10
UniProt:Q9HAU5 UPF2	1	UPF2 [cytosol] (R-HSA-927799)	0.897	9
UniProt:Q92900 UPF1	2	UPF1 [cytosol] (R-HSA-927734) p-4S-UPF1 [cytosol] (R-HSA-927856)	0.886	11
UniProt:P38919 EIF4A3	2	EIF4A3 [cytosol] (R-HSA-927868) EIF4A3 [nucleoplasm] (R-HSA-8849149)	0.883	9
UniProt:P61326 MAGOH	1	MAGOH [nucleoplasm] (R-HSA-156658)	0.773	7
UniProt:Q15287 RNPS1	2	RNPS1 [nucleoplasm] (R-HSA-156778) RNPS1 [cytosol] (R-HSA-159256)	0.643	3
UniProt:O15234 CASC3	2	CASC3 [nucleoplasm] (R-HSA-8849148) CASC3 [cytosol] (R-HSA-927807)	0.643	3
UniProt:Q92900-2 UPF1			0.527	2
UniProt:Q9UBU9 NXF1	2	NXF1 [nucleoplasm] (R-HSA-111690) NXF1 [cytosol] (R-HSA-156481)	0.527	2

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