Reactome | EEF1G [cytosol]

EEF1G [cytosol]

Stable Identifier

R-HSA-156925

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

EF-1-gamma, Elongation factor 1-gamma, eEF1B gamma

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P26641 EEF1G

Gene Names

EEF1G, EF1G, PRO1608

Chain

initiator methionine:, chain:2-437

Reference Genes

COSMIC (genes):EEF1G EEF1G

dbSNP Gene:1937 EEF1G

ENSEMBL:ENSG00000254772 EEF1G

Participates

as an input of

Formation of eEF1B complex (Homo sapiens)

as a component of

eEF1B complex [cytosol] (Homo sapiens)

Other forms of this molecule

EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol]

EEF1G(1-343)-ALK(1106-1620) fusion [cytosol]

Inferred To

efa1G [cytosol] (Dictyostelium discoideum)

Homologues of EEF1G [cytosol] (Sus scrofa)

TUT1 [cytosol] (Bos taurus)

CAM1 [cytosol] (Saccharomyces cerevisiae)

EEF1G [cytosol] (Canis familiaris)

EEF1G [cytosol] (Schizosaccharomyces pombe)

EEF1G [cytosol] (Sus scrofa)

Eef1g [cytosol] (Mus musculus)

Eef1g [cytosol] (Rattus norvegicus)

eEF1gamma [cytosol] (Drosophila melanogaster)

Interactors (28)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P24534 EEF1B2	1	EEF1B2 [cytosol] (R-HSA-156926)	0.885	12
UniProt:P29692 EEF1D	1	EEF1D [cytosol] (R-HSA-156914)	0.813	8
UniProt:P29692-2 EEF1D			0.666	4
UniProt:Q05639 EEF1A2	1	EEF1A2 [cytosol] (R-HSA-3907261)	0.643	5
UniProt:P26640 VARS1	1	VARS [cytosol] (R-HSA-379648)	0.643	4
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.643	5
UniProt:P68104 EEF1A1	7	EEF1A1 [lysosomal membrane] (R-HSA-9626022) EEF1A1 [cytosol] (R-HSA-156905) EEF1A1 [secretory granule lumen] (R-HSA-6801479) EEF1A1 [extracellular region] (R-HSA-6806456) EEF1A1 [ficolin-1-rich granule lumen] (R-HSA-6801528) Me3K318-EEF1A1 [cytosol] (R-HSA-8932419) Me3K79-EEF1A1 [cytosol] (R-HSA-8932212)	0.643	5
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	14
UniProt:P14679-2 P146792			0.556	3
UniProt:P32497	1	NIP1 [cytosol] (R-SCE-72550)	0.556	3
UniProt:P49090	1	ASNS [cytosol] (R-SCE-70597-2)	0.556	3
UniProt:Q9HB07 MYG1			0.556	3
UniProt:P40560 YIA1			0.556	3
UniProt:P32601 DSS4			0.556	3
UniProt:P31930 UQCRC1	1	UQCRC1 [mitochondrial inner membrane] (R-HSA-164284)	0.556	3
UniProt:Q8WUW1 BRK1	1	BRK1 [cytosol] (R-HSA-1671645)	0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q16512 PKN1	3	p-T774-PKN1 [cytosol] (R-HSA-5623651) PKN1 [cytosol] (R-HSA-5623613) p-T774-PKN1 [nucleoplasm] (R-HSA-5625721)	0.556	3
UniProt:Q13011 ECH1	3	ECH1 [mitochondrial matrix] (R-HSA-9838037) ECH1(1-328) [peroxisomal matrix] (R-HSA-9033140) ECH1(1-328) [cytosol] (R-HSA-9033152)	0.553	2
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:P49589 CARS1	3	CARS [cytosol] (R-HSA-379602) CARS1(2-606)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711977) CARS1(2-606)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711974)	0.527	3
UniProt:P48039 MTNR1A	1	MTNR1A [plasma membrane] (R-HSA-419316)	0.527	2
UniProt:P01106 MYC	2	MYC [nucleoplasm] (R-HSA-188379) PolyUb-MYC [nucleoplasm] (R-HSA-6783169)	0.527	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q9NPJ1 MKKS	1	MKKS [cytosol] (R-HSA-5624086)	0.527	2
UniProt:O15357 INPPL1	1	INPPL1 [cytosol] (R-HSA-913354)	0.527	3
UniProt:Q969Q1 TRIM63	1	TRIM63 [cytosol] (R-HSA-976020)	0.508	2
UniProt:A0A096LP01 SIM26			0.462	2