Reactome | EEF1G [cytosol]

EEF1G [cytosol]

Stable Identifier

R-HSA-156925

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

EF-1-gamma, Elongation factor 1-gamma, eEF1B gamma

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P26641 EEF1G

Gene Names

EEF1G, EF1G, PRO1608

Chain

initiator methionine:1, chain:2-437

Reference Genes

BioGPS Gene:1937 EEF1G

COSMIC (genes):EEF1G EEF1G

CTD Gene:1937 EEF1G

dbSNP Gene:1937 EEF1G

ENSEMBL:ENSG00000254772 EEF1G

HGNC:3213 EEF1G

KEGG Gene (Homo sapiens):1937 EEF1G

Monarch:1937 EEF1G

NCBI Gene:1937 EEF1G

OMIM:130593 EEF1G

Reference Transcript

RefSeq:NM_001404.4 EEF1G

Other Identifiers

0003940408

11726318_s_at

11753342_x_at

11753592_x_at

16739276

1676_s_at

17063066

1937

200689_3p_x_at

200689_x_at

211345_3p_x_at

211345_x_at

211927_3p_x_at

211927_x_at

3073748

3073750

3073751

3073752

3073753

3073755

3073756

3073757

3073758

3375806

3375807

3375809

3375811

3375815

3375816

3375817

3375820

3375822

3375824

3375825

3375826

3375829

3988067

3988082

3988084

73099_at

7948679

A_23_P13344

A_24_P287198

A_24_P467358

GE61363

GO:0003674

GO:0003723

GO:0003746

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005737

GO:0005783

GO:0005829

GO:0006412

GO:0006414

GO:0008135

GO:0008150

GO:0009058

GO:0009615

GO:0016020

GO:0034641

GO:0043226

GO:0045296

GO:0070062

Hs.2186.3.S1_3p_a_at

Hs.2186.3.S1_3p_x_at

ILMN_1680437

ILMN_2262288

M55409_s_at

PH_hs_0029532

TC11003185.hg

TC11003483.hg

g4503480_3p_a_at

g7770136_3p_a_at

Participant Of

input

Formation of eEF1B complex

hasComponent

eEF1B complex [cytosol]

Inferred To

efa1G [cytosol] (Dictyostelium discoideum)

Homologues of EEF1G [cytosol] (Canis familiaris)

Homologues of EEF1G [cytosol] (Sus scrofa)

eef1g [cytosol] (Danio rerio)

tef3 [cytosol] (Schizosaccharomyces pombe)

CAM1 [cytosol] (Saccharomyces cerevisiae)

EEF1G [cytosol] (Canis familiaris)

EEF1G [cytosol] (Plasmodium falciparum)

EEF1G [cytosol] (Sus scrofa)

EEF1G [cytosol] (Xenopus tropicalis)

Eef1g [cytosol] (Mus musculus)

Eef1g [cytosol] (Rattus norvegicus)

eEF1gamma [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_001395.1

Target Pathogen

5b354852be737e166372e7b8

OpenTargets

ENSG00000254772

HPA

ENSG00000254772-EEF1G

GeneCards

P26641

Ensembl

ENST00000329251, ENSP00000331901, ENSG00000254772

PRO

P26641

PDB

5DQS, 5JPO, 1PBU

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P24534 EEF1B2	1	EEF1B2 [cytosol] (R-HSA-156926)	0.801	9
UniProt:P29692 EEF1D	1	EEF1D [cytosol] (R-HSA-156914)	0.681	4
UniProt:P29692-2 EEF1D			0.666	4
UniProt:P14679-2 P146792			0.556	3
UniProt:P32497	1	NIP1 [cytosol] (R-SCE-72550)	0.556	3
UniProt:P49090	1	ASN2 [cytosol] (R-SCE-70597-2)	0.556	3
UniProt:P40560 YIA1			0.556	3
UniProt:P32601 DSS4			0.556	3
UniProt:P31930 UQCRC1	1	UQCRC1 [mitochondrial inner membrane] (R-HSA-164284)	0.556	3
UniProt:Q8WUW1 BRK1	1	BRK1 [cytosol] (R-HSA-1671645)	0.556	3
UniProt:Q9HB07 MYG1			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q16512 PKN1	3	PKN1 [cytosol] (R-HSA-5623613) p-T774-PKN1 [cytosol] (R-HSA-5623651) p-T774-PKN1 [nucleoplasm] (R-HSA-5625721)	0.556	3
UniProt:Q13011 ECH1	2	ECH1(1-328) [cytosol] (R-HSA-9033152) ECH1(1-328) [peroxisomal matrix] (R-HSA-9033140)	0.553	2
UniProt:P00533 EGFR	59	p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR A289V [plasma membrane] (R-HSA-1996334) p-6Y-EGFR T263P [plasma membrane] (R-HSA-1996336) p-6Y-EGFR G598V [plasma membrane] (R-HSA-1996339) p-6Y-EGFR R108K [plasma membrane] (R-HSA-1996338) p-6Y-EGFR A289T [plasma membrane] (R-HSA-1996341) p-6Y-EGFR G719C [plasma membrane] (R-HSA-1177530) p-6Y-EGFR A289D [plasma membrane] (R-HSA-1996340) p-6Y-EGFR G719A [plasma membrane] (R-HSA-1177528) EGFR L858R;T790M [plasma membrane] (R-HSA-1181386) EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1181399) EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996322) EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996325) EGFR M766_A767insASV [plasma membrane] (R-HSA-1996326) EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996317) EGFR L858R [plasma membrane] (R-HSA-1173212) EGFR G719S [plasma membrane] (R-HSA-1169418) EGFR E746_A750del [plasma membrane] (R-HSA-1181211) EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228010) EGFR A289V [plasma membrane] (R-HSA-1996321) EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228012) EGFR L747_T751del [plasma membrane] (R-HSA-1228015) EGFR A289D [plasma membrane] (R-HSA-1996327) EGFR L861Q [plasma membrane] (R-HSA-1177542) EGFR R108K [plasma membrane] (R-HSA-1996330) EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228034) EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228031) EGFR G719A [plasma membrane] (R-HSA-1177532) EGFR A289T [plasma membrane] (R-HSA-1996306) EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228025) EGFR G719C [plasma membrane] (R-HSA-1177531) EGFR T263P [plasma membrane] (R-HSA-1996315) EGFR G598V [plasma membrane] (R-HSA-1996314) EGFR L747_S752del [plasma membrane] (R-HSA-1228016) EGFR [endosome membrane] (R-HSA-9611160) p-4Y-EGFR [plasma membrane] (R-HSA-180287) p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane] (R-HSA-8864019) p-Y1086,Y1101-EGFR [plasma membrane] (R-HSA-179868) EGFR [plasma membrane] (R-HSA-179837) p-6Y-EGFR [plasma membrane] (R-HSA-179803)	0.553	2
UniProt:P48039 MTNR1A	1	MTNR1A [plasma membrane] (R-HSA-419316)	0.527	2
UniProt:P01106 MYC	2	PolyUb-MYC [nucleoplasm] (R-HSA-6783169) MYC [nucleoplasm] (R-HSA-188379)	0.527	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q969Q1 TRIM63	1	TRIM63 [cytosol] (R-HSA-976020)	0.508	2

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