Reactome | EEF1B2 [cytosol]

EEF1B2 [cytosol]

Stable Identifier

R-HSA-156926

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

EF-1-beta, Elongation factor 1-beta, eEF1B beta

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P24534 EEF1B2

Gene Names

EEF1B2, EEF1B, EF1B

Chain

initiator methionine:, chain:2-225

Reference Genes

BioGPS Gene:1933 EEF1B2

COSMIC (genes):EEF1B2 EEF1B2

CTD Gene:1933 EEF1B2

dbSNP Gene:1933 EEF1B2

ENSEMBL:ENSG00000114942 EEF1B2

HGNC:3208 EEF1B2

KEGG:hsa:1933 EEF1B2

Monarch:1933 EEF1B2

NCBI Gene:1933 EEF1B2

OMIM:600655 EEF1B2

UCSC:P24534 EEF1B2

Reference Transcript

Other Identifiers

11720183_s_at

11720184_x_at

11757149_at

11757150_x_at

16889938

16889954

17119224

1933

200705_PM_s_at

200705_s_at

2524579

2524580

2524581

2524582

2524583

2524584

2524585

2524586

2524587

2524588

2524589

2524590

2524591

2524592

2524593

2524594

2524595

2524596

2524597

2524598

2524599

2524600

2524601

2860353

3073096

3073097

3073098

3073102

3073104

35748_at

3594257

4003081

4003083

4003085

4003087

8047771

8047778

8047780

A_14_P113407

A_21_P0000272

A_21_P0000273

A_23_P165535

GE79016

GO:0003746

GO:0005085

GO:0005515

GO:0005737

GO:0005783

GO:0005829

GO:0005853

GO:0006412

GO:0006414

GO:0043226

GO:0045182

GO:0098772

HMNXSV003000332

HMNXSV003015623

HMNXSV003023494

ILMN_1675541

ILMN_1685678

ILMN_1694587

ILMN_1701930

ILMN_2318725

PH_hs_0019741

PH_hs_0039722

RNA33511|snoRNA_scaRNA_107_132

RNA33758|snoRNA_scaRNA_354_70

TC02001212.hg

TC02001213.hg

X60489_at

g4503476_3p_s_at

Participates

as an input of

Formation of eEF1B complex (Homo sapiens)

as a component of

eEF1B complex [cytosol] (Homo sapiens)

Inferred To

eEF1beta [cytosol] (Drosophila melanogaster)

EEF1B [cytosol] (Bos taurus)

Eef1b [cytosol] (Mus musculus)

EFB1 [cytosol] (Saccharomyces cerevisiae)

EEF1B2 [cytosol] (Canis familiaris)

EEF1B2 [cytosol] (Gallus gallus)

EEF1B2 [cytosol] (Plasmodium falciparum)

EEF1B2 [cytosol] (Sus scrofa)

tef5 [cytosol] (Schizosaccharomyces pombe)

Eef1b2 [cytosol] (Rattus norvegicus)

eef-1B.1 [cytosol] (Caenorhabditis elegans)

efa1B [cytosol] (Dictyostelium discoideum)

eef1b [cytosol] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000636275, ENST00000635728, ENSP00000490326, ENST00000236957, ENSP00000236957, ENSG00000114942, ENSG00000283391, ENSP00000489993, ENSP00000376056, ENST00000392222

OpenTargets

ENSG00000114942

GeneCards

EEF1B2

HPA

ENSG00000114942-EEF1B2

PRO

P24534

Pharos - Targets

P24534

GlyGen

P24534

HMDB Protein

HMDBP08367

PDB

5DQS, 1B64

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P26641 EEF1G	3	EEF1G [cytosol] (R-HSA-156925) EEF1G(1-343)-ALK(1106-1620) fusion [cytosol] (R-HSA-9710839) EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol] (R-HSA-9710850)	0.885	12
UniProt:Q05639 EEF1A2	1	EEF1A2 [cytosol] (R-HSA-3907261)	0.669	5
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	7
UniProt:Q8WW59 SPRY4			0.556	3
UniProt:P26641-2 EEF1G			0.556	3
UniProt:P55198 AF17			0.527	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P68104 EEF1A1	7	EEF1A1 [lysosomal membrane] (R-HSA-9626022) EEF1A1 [cytosol] (R-HSA-156905) EEF1A1 [ficolin-1-rich granule lumen] (R-HSA-6801528) EEF1A1 [extracellular region] (R-HSA-6806456) EEF1A1 [secretory granule lumen] (R-HSA-6801479) Me3K318-EEF1A1 [cytosol] (R-HSA-8932419) Me3K79-EEF1A1 [cytosol] (R-HSA-8932212)	0.527	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	12

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