NEXT2 fragment of NOTCH2 is further cleaved at the S3 site by the gamma-secretase complex, which releases the intracellular domain NICD2 into the cytosol (Saxena et al. 2001, De Strooper et al. 1999, Schroeter et al. 1998, Fortini 2002).
Saxena, MT, Schroeter, EH, Mumm, JS, Kopan, R
Groot, AJ, Habets, R, Yahyanejad, S, Hodin, CM, Reiss, K, Saftig, P, Theys, J, Vooijs, M
Fortini, ME
Schroeter, EH, Kisslinger, JA, Kopan, R
De Strooper, B, Annaert, W, Cupers, P, Saftig, P, Craessaerts, K, Mumm, JS, Schroeter, EH, Schrijvers, V, Wolfe, MS, Ray, WJ, Goate, A, Kopan, R
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