Reactome | Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC

Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC

Stable Identifier

R-HSA-158481

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

nuclear envelope, cytosol, nucleoplasm

ReviewStatus

5/5

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Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC

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The mature SLBP independent intronless histone mRNA is transported through the nucler pore to the cytoplasmic side (von Moeller et al.2013). This is a black box event since there is not physical evidence about how exactly occurs this transport.

Literature References

PubMed ID	Title	Journal	Year
2017161	Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps. Marzluff, WF, Schumperli, D, Schneiderman, MH, Ramamurthy, L, Harris, ME, Bohni, R	Mol Cell Biol	1991
23804756	Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins Marzluff, WF, Lerner, R, von Moeller, H, Ricciardi, A, Conti, E, Basquin, C	Nucleic Acids Res.	2013