fibrin multimer, crosslinked -> fibrin digestion products (plasmin)

Stable Identifier
R-HSA-158766
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Plasmin, generated at the surfaces of the fibrin clot by tissue plasminogen activator or at the surfaces of cells by urokinase plasminogen activator, catalyzes the hydrolysis of fibrin to soluble fragments (Chapman 1997).

Literature References
PubMed ID Title Journal Year
2318848 Characterization of the gene for human plasminogen, a key proenzyme in the fibrinolytic system

Petersen, TE, Martzen, MR, Ichinose, A, Davie, EW

J Biol Chem 1990
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
serine-type endopeptidase activity of Plasmin [extracellular region]
Physical Entity
Activity
Authored