Reactome: A Curated Pathway Database

fibrin multimer, crosslinked -> fibrin digestion products (plasmin)

Stable Identifier
R-HSA-158766
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Plasmin, generated at the surfaces of the fibrin clot by tissue plasminogen activator or at the surfaces of cells by urokinase plasminogen activator, catalyzes the hydrolysis of fibrin to soluble fragments (Chapman 1997).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
serine-type endopeptidase activity of Plasmin [extracellular region] Plasmin [extracellular region] serine-type endopeptidase activity (0004252)