plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein

Stable Identifier
R-HSA-158941
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein
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Extracellular plasminogen binds with high affinity to histidine-rich glycoprotein on the plasma membrane. Binding requires Zn++ in concentrations higher than those found in normal plasma, but that can be generated, e.g., by platelet activation (Jones et al. 2004).
Participants
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Output
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as an event of
This event is regulated
Requirements
Orthologous Events
plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Bos taurus)
plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Canis familiaris)
plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Gallus gallus)
plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Mus musculus)
plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Rattus norvegicus)
plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Sus scrofa)
plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Xenopus tropicalis)
Authored
D'Eustachio, P  (2005-02-14)
Created
D'Eustachio, P  (2005-02-14)
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