Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex

Stable Identifier
Reaction [dissociation]
Homo sapiens
Locations in the PathwayBrowser
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

At some point eIF4E binds the mature mRNA. While TAP and Aly/Ref are released and will be reycled back to the nucleoplasm (Hung et al.2010, Lindtner et al. 2002).

Literature References
PubMed ID Title Journal Year
20129943 Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1

Hung, ML, Hautbergue, GM, Snijders, AP, Dickman, MJ, Wilson, SA

Nucleic Acids Res. 2010
12003494 An element in the 3' untranslated region of human LINE-1 retrotransposon mRNA binds NXF1(TAP) and can function as a nuclear export element

Lindtner, S, Felber, BK, Kjems, J

RNA 2002
Participant Of
Event Information
Go Biological Process
This event is regulated
Orthologous Events
Cite Us!