Reactome | GABPA [nucleoplasm]

GABPA [nucleoplasm]

Stable Identifier

R-HSA-1592206

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

NRF2 alpha subunit, GA-binding protein alpha chain, GABPA_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q06546 GABPA

Gene Names

GABPA, E4TF1A

Chain

chain:1-454

Reference Genes

BioGPS Gene:2551 GABPA

COSMIC (genes):GABPA GABPA

CTD Gene:2551 GABPA

dbSNP Gene:2551 GABPA

ENSEMBL:ENSG00000154727 GABPA

HGNC:4071 GABPA

KEGG Gene (Homo sapiens):2551 GABPA

Monarch:2551 GABPA

NCBI Gene:2551 GABPA

OMIM:600609 GABPA

UCSC:Q06546 GABPA

Reference Transcript

Other Identifiers

0001990458

11722717_a_at

11755033_a_at

16921850

210188_at

227428_at

2551

3004044

3004292

3004294

3004295

3004296

3004297

37245_at

3916577

3916578

3916579

3916580

3916581

3916582

3916583

3916585

3916586

3916587

3916588

3916595

3916597

3916599

3916600

3916603

3916605

3916606

3916607

3916611

3916612

3916613

3916614

3916615

62479_at

8068039

8133030

A_23_P166219

A_33_P3269588

GE58938

GO:0000122

GO:0000228

GO:0000790

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0001701

GO:0001825

GO:0002376

GO:0003674

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0006355

GO:0006357

GO:0007005

GO:0008134

GO:0008150

GO:0009058

GO:0009790

GO:0010628

GO:0030154

GO:0033613

GO:0034641

GO:0042025

GO:0043226

GO:0043565

GO:0045653

GO:0045944

GO:0048646

GO:0048856

GO:1903351

GO:1990837

Hs.5905.0.A1_3p_at

ILMN_1750029

ILMN_2175562

PH_hs_0040994

TC21000078.hg

U13044_at

g286026_3p_at

Participant Of

output

Expression of GABPA (NRF2 alpha subunit)

input

Formation of NRF2

hasComponent

NRF2 [nucleoplasm]

Inferred To

Gabpa [nucleoplasm] (Mus musculus)

Gabpa [nucleoplasm] (Rattus norvegicus)

Ets97D [nucleoplasm] (Drosophila melanogaster)

gabpa [nucleoplasm] (Danio rerio)

gabpa [nucleoplasm] (Xenopus tropicalis)

GABPA [nucleoplasm] (Bos taurus)

GABPA [nucleoplasm] (Canis familiaris)

GABPA [nucleoplasm] (Gallus gallus)

GABPA [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

XP_011527822.1, XP_005260995.1, XP_016883802.1, NP_002031.2, NP_001184226.1, XP_011527823.1

OpenTargets

ENSG00000154727

HPA

ENSG00000154727-GABPA

GeneCards

Q06546

Ensembl

ENST00000354828, ENSP00000346886, ENST00000400075, ENSP00000382948, ENSG00000154727

PRO

Q06546

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TAK5 GABP2			0.675	4
UniProt:O75716 STK16			0.556	3
UniProt:Q5TFG8 ZC21B			0.556	3
UniProt:Q06547 GABPB1			0.556	3
UniProt:P08047 SP1	1	SP1 [nucleoplasm] (R-HSA-1592223)	0.544	2
UniProt:Q02447 SP3	3	SUMO2-K551-SP3 [nucleoplasm] (R-HSA-6804456) SP3 [nucleoplasm] (R-HSA-2160951) SUMO1-K551-SP3 [nucleoplasm] (R-HSA-3247472)	0.544	2
UniProt:P51610 HCFC1	2	K48polyUb,K63polyUb-HCFC1 [nucleoplasm] (R-HSA-5690821) HCFC1 [nucleoplasm] (R-HSA-1592209)	0.499	2