Conjugation of carboxylic acids

Stable Identifier
R-HSA-159424
Type
Pathway
Species
Homo sapiens
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Xenobiotics and endogenous compounds containing carboxylate groups can be activated with coenzyme A to produce acyl-CoA thioesters and then conjugated with the amino groups of glycine or glutamine to form amide-linked conjugates. Clinically important substrates include benzoic acid, phenylacetic acid, and salicylic acid.

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