GLYAT-like proteins transfer glycine to ST-CoA to form SUA

Stable Identifier
R-HSA-159574
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
salicylate-CoA + glycine => salicyluric acid + Coenzyme A, Salicylate-CoA forms an amide bond with glycine
ReviewStatus
5/5
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Salicylate-CoA (ST-CoA) and glycine react to form salicyluric acid and coenzyme A (Mawal and Qureshi 1994).
Literature References
PubMed ID Title Journal Year
7802672 Purification to homogeneity of mitochondrial acyl coa:glycine n-acyltransferase from human liver

Qureshi, IA, Mawal, YR

Biochem Biophys Res Commun 1994
931988 Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man

Strong, JM, Mieyal, JJ, Lucas, SV, Webster, LT, Siddiqui, UA

J Biol Chem 1976
Participants
Participates
Catalyst Activity

glycine N-benzoyltransferase activity of GLYAT-like proteins [mitochondrial matrix]

Orthologous Events
Reviewed
Created
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