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IMPA2 [cytosol]
Stable Identifier
R-HSA-1604572
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
IMP.18P
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP2, IP, and Ins in the cytosol (Homo sapiens)
I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Homo sapiens)
IMPA1/2 [cytosol] (Homo sapiens)
IMPA2 dimer [cytosol] (Homo sapiens)
IMPA2:Mg2+ [cytosol] (Homo sapiens)
IMPA2 [cytosol] (Homo sapiens)
I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Homo sapiens)
IMPA1/2 [cytosol] (Homo sapiens)
IMPA2 dimer [cytosol] (Homo sapiens)
IMPA2:Mg2+ [cytosol] (Homo sapiens)
IMPA2 [cytosol] (Homo sapiens)
I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Homo sapiens)
IMPA1/2 [cytosol] (Homo sapiens)
IMPA2 dimer [cytosol] (Homo sapiens)
IMPA2:Mg2+ [cytosol] (Homo sapiens)
IMPA2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14732 IMPA2
Gene Names
IMPA2, IMP.18P
Chain
chain:1-288
Reference Genes
BioGPS Gene:3613 IMPA2
COSMIC (genes):IMPA2 IMPA2
CTD Gene:3613 IMPA2
dbSNP Gene:3613 IMPA2
ENSEMBL:ENSG00000141401 IMPA2
ENSEMBL_homo_sapiens_GENE:ENSG00000141401.12 IMPA2
HGNC:6051 IMPA2
KEGG Gene (Homo sapiens):3613 IMPA2
Monarch:3613 IMPA2
NCBI Gene:3613 IMPA2
OMIM:605922 IMPA2
UCSC:O14732 IMPA2
Reference Transcript
RefSeq:NM_014214.2 IMPA2
Other Identifiers
11717496_a_at
16851026
203126_PM_at
203126_at
3613
36496_at
3779365
3779366
3779374
3779382
3779384
3779390
3779396
3779398
3779399
3779400
3779401
64327_at
8020183
A_23_P50081
A_33_P3290403
GE58573
GO:0003824
GO:0005515
GO:0005737
GO:0005829
GO:0005975
GO:0006020
GO:0006021
GO:0006629
GO:0006796
GO:0007165
GO:0008934
GO:0010226
GO:0016787
GO:0023052
GO:0042803
GO:0046854
GO:0046872
GO:0052832
GO:0052833
GO:0052834
HMNXSV003050260
ILMN_2094061
PH_hs_0000585
PH_hs_0035840
TC18000060.hg
g7657235_3p_at
Participates
as a component of
IMPA2:Mg2+ [cytosol] (Homo sapiens)
Inferred To
Homologues of IMPA2 [cytosol]
(Drosophila melanogaster)
Homologues of IMPA2 [cytosol]
(Saccharomyces cerevisiae)
IMPA2 [cytosol]
(Bos taurus)
IMPA2 [cytosol]
(Caenorhabditis elegans)
IMPA2 [cytosol]
(Canis familiaris)
IMPA2 [cytosol]
(Danio rerio)
IMPA2 [cytosol]
(Dictyostelium discoideum)
IMPA2 [cytosol]
(Drosophila melanogaster)
IMPA2 [cytosol]
(Gallus gallus)
IMPA2 [cytosol]
(Mus musculus)
IMPA2 [cytosol]
(Rattus norvegicus)
IMPA2 [cytosol]
(Saccharomyces cerevisiae)
IMPA2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_055029.1
Guide to Pharmacology - Targets
1464
OpenTargets
ENSG00000141401
ZINC - Substances
IMPA2_HUMAN
ZINC target
O14732
PRO
O14732
PDB
2CZI
,
2FVZ
,
2CZH
,
2CZK
,
2DDK
GeneCards
O14732
HPA
ENSG00000141401-IMPA2
Ensembl
ENSP00000269159
,
ENSG00000141401
,
ENST00000269159
Pharos - Targets
O14732
ZINC - Predictions - Purchasable
IMPA2_HUMAN
HMDB Protein
HMDBP01118
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8TBC4 UBA3
2
UBA3 [cytosol]
(R-HSA-947632)
G76-NEDD8-C237-UBA3 [cytosol]
(R-HSA-8951640)
0.718
6
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