Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
INPP5E [cytosol]
Stable Identifier
R-HSA-1604585
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser for interactor UniProt:O43924 PDE6D
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Cilium Assembly (Homo sapiens)
Cargo trafficking to the periciliary membrane (Homo sapiens)
ARL13B-mediated ciliary trafficking of INPP5E (Homo sapiens)
PDE6D binds INPP5E (Homo sapiens)
INPP5E [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NRR6 INPP5E
Gene Names
INPP5E
Chain
chain:1-641, propeptide:642-644
Reference Genes
BioGPS Gene:56623 INPP5E
COSMIC (genes):INPP5E INPP5E
CTD Gene:56623 INPP5E
dbSNP Gene:56623 INPP5E
ENSEMBL:ENSG00000148384 INPP5E
ENSEMBL_homo_sapiens_GENE:ENSG00000148384.14 INPP5E
HGNC:21474 INPP5E
KEGG Gene (Homo sapiens):56623 INPP5E
Monarch:56623 INPP5E
NCBI Gene:56623 INPP5E
OMIM:613037 INPP5E
UCSC:Q9NRR6 INPP5E
Reference Transcript
RefSeq:NM_001318502.1 INPP5E
RefSeq:NM_019892.5 INPP5E
Other Identifiers
11720872_at
11752727_a_at
17099967
204706_PM_at
204706_at
3229996
3229997
3229998
3229999
3230000
3230003
3230005
3230006
3230007
3230008
3230011
3230013
3230018
3230019
3230020
3230021
3230022
3230023
3230025
39323_at
56623
8165171
83145_at
A_23_P94875
A_24_P317835
GE59181
GO:0000139
GO:0001726
GO:0003824
GO:0004439
GO:0004445
GO:0005634
GO:0005737
GO:0005794
GO:0005829
GO:0005856
GO:0005886
GO:0005929
GO:0005930
GO:0006629
GO:0006661
GO:0008150
GO:0016020
GO:0016314
GO:0016787
GO:0016791
GO:0017148
GO:0019637
GO:0023052
GO:0032580
GO:0034485
GO:0036092
GO:0042995
GO:0043226
GO:0043813
GO:0046488
GO:0046856
GO:0051898
GO:0106019
GO:1903565
HMNXSV003006513
HMNXSV003053394
ILMN_1811301
PH_hs_0002212
TC09001731.hg
U45974_at
g9845290_3p_at
Participates
as a component of
PDE6D:INPP5E [cytosol] (Homo sapiens)
as an input of
PDE6D binds INPP5E (Homo sapiens)
as a member of
OCRL/INPP5E [cytosol] (Homo sapiens)
Other forms of this molecule
INPP5E [cilium]
Inferred To
INPP5E [cytosol]
(Bos taurus)
INPP5E [cytosol]
(Canis familiaris)
INPP5E [cytosol]
(Gallus gallus)
INPP5E [cytosol]
(Sus scrofa)
Inpp5e [cytosol]
(Mus musculus)
Inpp5e [cytosol]
(Rattus norvegicus)
inpp5e [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_063945.2
,
NP_001305431.1
Guide to Pharmacology - Targets
1456
OpenTargets
ENSG00000148384
IntEnz
3.1.3.36
HPA
ENSG00000148384-INPP5E
GeneCards
Q9NRR6
Ensembl
ENST00000676019
,
ENSP00000501984
,
ENST00000371712
,
ENSG00000148384
,
ENSP00000360777
PRO
Q9NRR6
Pharos - Targets
Q9NRR6
Orphanet
18603
HMDB Protein
HMDBP01572
PDB
2XSW
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.744
4
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.725
4
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.725
5
UniProt:O43924 PDE6D
2
PDE6D [cilium]
(R-HSA-5624884)
PDE6D [cytosol]
(R-HSA-2565921)
0.725
5
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text