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INPP5J [cytosol]
Stable Identifier
R-HSA-1604590
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
PIB5PA, PIPP
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP2, IP, and Ins in the cytosol (Homo sapiens)
I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Homo sapiens)
INPP5(4) [cytosol] (Homo sapiens)
INPP5J [cytosol] (Homo sapiens)
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Homo sapiens)
INPP5(3)/ITPK1 [cytosol] (Homo sapiens)
INPP5J [cytosol] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the plasma membrane (Homo sapiens)
PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Homo sapiens)
INPP5(2) [cytosol] (Homo sapiens)
INPP5J [cytosol] (Homo sapiens)
PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Homo sapiens)
SYNJ/INPP5(1) [cytosol] (Homo sapiens)
INPP5(1) [cytosol] (Homo sapiens)
INPP5J [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15735 INPP5J
Gene Names
INPP5J, PIB5PA, PIPP
Chain
chain:1-1006
Reference Genes
BioGPS Gene:27124 INPP5J
COSMIC (genes):INPP5J INPP5J
CTD Gene:27124 INPP5J
dbSNP Gene:27124 INPP5J
ENSEMBL:ENSG00000185133 INPP5J
HGNC:8956 INPP5J
KEGG Gene (Homo sapiens):27124 INPP5J
Monarch:27124 INPP5J
NCBI Gene:27124 INPP5J
OMIM:606481 INPP5J
UCSC:Q15735 INPP5J
Reference Transcript
RefSeq:NM_001284288.1 INPP5J
RefSeq:NM_001002837.2 INPP5J
RefSeq:NM_001284285.1 INPP5J
RefSeq:XM_017028771.1 INPP5J
RefSeq:NM_001284289.1 INPP5J
Other Identifiers
0006290427
11723604_a_at
11746630_x_at
11750267_x_at
16929118
213651_at
27124
38960_at
3942767
3942768
3942769
3942770
3942771
3942773
3942774
3942775
3942776
3942777
3942778
3942779
3942780
3942781
3942784
3942786
3942788
3942790
3942791
3942793
3942794
3942797
3942799
3942800
3942801
3942802
8072436
A_14_P107045
A_24_P284805
GE59182
GO:0001726
GO:0003674
GO:0004439
GO:0004445
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0005975
GO:0006464
GO:0006629
GO:0006661
GO:0007010
GO:0008150
GO:0009056
GO:0009058
GO:0010977
GO:0016787
GO:0016791
GO:0017124
GO:0019898
GO:0022607
GO:0030154
GO:0030426
GO:0031115
GO:0033137
GO:0034485
GO:0043198
GO:0043647
GO:0044281
GO:0046855
GO:0046856
GO:0048856
GO:0052658
GO:0052659
GO:0065003
Hs.21492.0.S1_3p_at
ILMN_1670668
ILMN_1777644
ILMN_3241087
PH_hs_0031056
TC22001429.hg
U45975_at
Participant Of
hasMember
INPP5(1) [cytosol]
INPP5(2) [cytosol]
INPP5(3)/ITPK1 [cytosol]
INPP5(4) [cytosol]
Inferred To
INPP5J [cytosol] (Bos taurus)
INPP5J [cytosol] (Canis familiaris)
INPP5J [cytosol] (Plasmodium falciparum)
INPP5J [cytosol] (Sus scrofa)
inpp-1 [cytosol] (Caenorhabditis elegans)
Inpp5j [cytosol] (Mus musculus)
Inpp5j [cytosol] (Rattus norvegicus)
Dmel\CG9784 [cytosol] (Drosophila melanogaster)
inpp5jb [cytosol] (Danio rerio)
sipa1l3 [cytosol] (Xenopus tropicalis)
INP54 [cytosol] (Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001002837.1
,
NP_001271217.1
,
NP_001271218.1
,
NP_001271214.1
,
XP_016884260.1
OpenTargets
ENSG00000185133
IntEnz
3.1.3.56
GeneCards
Q15735
HPA
ENSG00000185133-INPP5J
Ensembl
ENSG00000185133
,
ENSP00000333262
,
ENSP00000384596
,
ENST00000400294
,
ENST00000405300
,
ENST00000404390
,
ENSP00000384534
,
ENST00000331075
,
ENSP00000383150
PRO
Q15735
HMDB Protein
HMDBP00363
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08379 GOLGA2
3
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.718
6
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:Q96FA3 PELI1
2
PELI1 [cytosol]
(R-HSA-450696)
p-PELI1 [cytosol]
(R-HSA-450815)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
PICK1 [plasma membrane]
(R-HSA-416989)
0.556
3
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