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MMP15 [plasma membrane]
Stable Identifier
R-HSA-1605823
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
MT2-MMP, Matrix metalloproteinase-15, MMP15_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Activation of Matrix Metalloproteinases (Homo sapiens)
MT-MMPs are sorted to the plasma membrane (Homo sapiens)
MT-MMPs [plasma membrane] (Homo sapiens)
MMP15 [plasma membrane] (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type I degradation by MMP15 (Homo sapiens)
MMP15 [plasma membrane] (Homo sapiens)
Collagen type II degradation by MMP15 (Homo sapiens)
MMP15 [plasma membrane] (Homo sapiens)
Collagen type III degradation by MMP15 (Homo sapiens)
MMP15 [plasma membrane] (Homo sapiens)
HSPG2 (perlecan) degradation by MMP14, MMP15 (Homo sapiens)
MMP14, MMP15 [plasma membrane] (Homo sapiens)
MMP15 [plasma membrane] (Homo sapiens)
NID1 degradation by MMP14, MMP15 (Homo sapiens)
MMP14, MMP15 [plasma membrane] (Homo sapiens)
MMP15 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51511 MMP15
Gene Names
MMP15
Chain
signal peptide:1-41, propeptide:42-131, chain:132-669
Reference Genes
BioGPS Gene:4324 MMP15
COSMIC (genes):MMP15 MMP15
CTD Gene:4324 MMP15
dbSNP Gene:4324 MMP15
ENSEMBL:ENSG00000102996 MMP15
HGNC:7161 MMP15
KEGG Gene (Homo sapiens):4324 MMP15
Monarch:4324 MMP15
NCBI Gene:4324 MMP15
OMIM:602261 MMP15
UCSC:P51511 MMP15
Reference Transcript
RefSeq:NM_002428.3 MMP15
Other Identifiers
0004280458
1167_s_at
11719977_a_at
11719978_a_at
1302_s_at
160037_at
16819653
203365_s_at
243883_at
2611
3663076
3663077
3663089
3663090
3663093
3663095
3663098
3663099
3663100
3663103
3663105
3663107
3663108
3663109
3663110
3663111
3663112
3663113
3663114
3663115
3663116
40390
4324
7996185
A0A024R6U8
A_14_P135168
A_23_P100177
A_24_P116535
AAH36495
AAH55428
ABJ53423
BAA13071
BAA22225
BC036495
BC055428
CAA88373
CAB002611
CCDS10792
CH471092
D85510
D86331
D86331_s_at
EAW82965
EAW82966
EF032329
ENSG00000102996
ENSP00000219271
ENST00000219271
ENST00000219271.3
EntrezGene:4324
EntrezGene:MMP15
g4505210_3p_s_at
GE60415
GO:0003674
GO:0004222
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005623
GO:0005886
GO:0005887
GO:0006464
GO:0006508
GO:0008047
GO:0008150
GO:0008233
GO:0008237
GO:0008270
GO:0009056
GO:0009790
GO:0016020
GO:0016021
GO:0016787
GO:0022617
GO:0030154
GO:0030198
GO:0030234
GO:0030574
GO:0031012
GO:0032355
GO:0035987
GO:0043085
GO:0043167
GO:0046872
GO:0048646
GO:0048856
GO:0070006
HGNC:7161
HPA040390
Hs.299334.0.A1_3p_at
ILMN_1718646
IPR000585
IPR001818
IPR002477
IPR006026
IPR018486
IPR018487
IPR021158
IPR021190
IPR021805
IPR024079
IPR028729
IPR033739
IPR036365
IPR036375
MIM:602261
MMP15
MMP15-201
NM_002428
NP_002419
PF00045
PF00413
PF01471
PF11857
PH_hs_0030825
PR00138
SM00120
SM00235
TC16000500.hg
UPI000003DC75
Z48482
Z48482_at
Participant Of
hasCandidate
MT-MMPs [plasma membrane]
hasMember
MMP14, MMP15 [plasma membrane]
Other forms of this molecule
MMP15 [Golgi lumen]
MMP15(42-669) [Golgi lumen]
Inferred To
Homologues of MMP15 [plasma membrane] (Caenorhabditis elegans)
Homologues of MMP15 [plasma membrane] (Drosophila melanogaster)
MMP15 [plasma membrane] (Bos taurus)
MMP15 [plasma membrane] (Caenorhabditis elegans)
MMP15 [plasma membrane] (Canis familiaris)
MMP15 [plasma membrane] (Danio rerio)
MMP15 [plasma membrane] (Drosophila melanogaster)
MMP15 [plasma membrane] (Gallus gallus)
MMP15 [plasma membrane] (Mus musculus)
MMP15 [plasma membrane] (Rattus norvegicus)
MMP15 [plasma membrane] (Sus scrofa)
MMP15 [plasma membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_002419.1
OpenTargets
ENSG00000102996
GeneCards
P51511
ZINC - Substances
MMP15_HUMAN
ZINC target
P51511
PRO
P51511
ZINC - Predictions - Purchasable
MMP15_HUMAN
HMDB Protein
HMDBP07804
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