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About
What is Reactome ?
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Team
Scientific Advisory Board
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Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
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Diseases
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Graph Database
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Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
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Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
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CUX1-FGFR1 fusion [cytosol]
Stable Identifier
R-HSA-1614371
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
CUX1(1-339)-FGFR1(429-822) fusion, t(7;8) CUX1-FGFR1 fusion
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)
Dimerization of cytosolic FGFR1 fusion proteins (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion mutant dimer [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion [cytosol] (Homo sapiens)
cytosolic FGFR1 fusion mutants [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion [cytosol] (Homo sapiens)
Phosphorylation of cytosolic FGFR1 fusion dimers (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion mutant dimer [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion [cytosol] (Homo sapiens)
Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation (Homo sapiens)
FGFR1 fusion mutant dimers:TKIs [cytosol] (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion mutant dimer [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion [cytosol] (Homo sapiens)
cytosolic FGFR1 fusion mutant dimers [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion mutant dimer [cytosol] (Homo sapiens)
CUX1-FGFR1 fusion [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
21330321
The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11)
Wasag, B
,
Lierman, E
,
Meeus, P
,
Cools, J
,
Vandenberghe, P
Haematologica
2011
External Reference Information
External Reference
UniProt:P39880 CUX1
Gene Names
CUX1, CUTL1
Chain
chain:1-1505, chain:756-1505
Reference Genes
BioGPS Gene:1523 CUX1
COSMIC (genes):CUX1 CUX1
CTD Gene:1523 CUX1
dbSNP Gene:1523 CUX1
ENSEMBL:ENSG00000257923 CUX1
Monarch:1523 CUX1
NCBI Gene:1523 CUX1
OMIM:116896 CUX1
UCSC:P39880 CUX1
Reference Transcript
RefSeq:NM_001202544.2 CUX1
RefSeq:NM_181552.3 CUX1
RefSeq:NM_001202545.2 CUX1
RefSeq:NM_181500.3 CUX1
RefSeq:NM_001202543.1 CUX1
Other Identifiers
0001690014
0002260019
11717338_a_at
11732370_a_at
11749496_a_at
11751749_a_at
1523
17049729
202367_at
214743_at
225935_at
225937_at
227069_at
3003473
3016381
3016382
3016384
3016385
3016400
3016414
3016423
3016431
3016433
3016436
3016438
3016455
3016460
3016462
3016465
3016467
3016469
3016471
3016472
3016473
3016474
3016475
3016476
3016477
3016478
3016479
3016492
3016493
3016494
3016496
3016498
3016499
3016500
3016501
3016502
3016503
3016504
3016505
3016506
3016507
3016508
3016510
3016511
3016512
3016513
3016514
3016516
3016518
3016520
3016521
3016522
3016523
3016625
3016627
3016628
3016629
3016630
3016631
3016632
3016634
3052946
31822_at
31823_at
48445_at
54869_at
8135114
87296_at
90590_at
A_14_P123491
A_23_P253375
A_24_P220454
A_24_P691604
A_33_P3298785
GE56961
GE56987
GE58066
GE62532
GO:0000122
GO:0000139
GO:0000228
GO:0000301
GO:0000790
GO:0000902
GO:0000977
GO:0000981
GO:0003674
GO:0003677
GO:0003700
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005794
GO:0005829
GO:0006355
GO:0006357
GO:0006810
GO:0006891
GO:0007275
GO:0008150
GO:0009058
GO:0016192
GO:0030154
GO:0030173
GO:0030674
GO:0034641
GO:0043226
GO:0043565
GO:0048193
GO:0048856
GO:0050775
GO:1990837
Hs.147049.1.S1_3p_at
Hs.19215.0.A1_3p_at
Hs.19215.0.A2_3p_at
Hs.77273.2.A1_3p_at
ILMN_1687567
ILMN_1744659
ILMN_2278636
ILMN_2330213
M74099_at
PH_hs_0016862
PH_hs_0025715
TC07002501.hg
g4503168_3p_at
Participant Of
hasMember
cytosolic FGFR1 fusion mutants [cytosol]
hasComponent
CUX1-FGFR1 fusion mutant dimer [cytosol]
Other forms of this molecule
CUX1-p-2Y-FGFR1 fusion [cytosol]
Modified Residues
Name
Insertion of residues 429 to 822 at 340 from UniProt:P11362 FGFR1
Coordinate
340
Disease
Name
Identifier
Synonyms
precursor lymphoblastic lymphoma/leukemia
5600
subacute leukemia
3264
myelodysplastic myeloproliferative cancer
4972
Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
Cross References
RefSeq
NP_852477.1
,
NP_001189473.1
,
NP_001189472.1
,
NP_001189474.1
,
NP_853530.2
OpenTargets
ENSG00000257923
GeneCards
P39880
Ensembl
ENSP00000409745
,
ENSP00000292535
,
ENST00000549414
,
ENSP00000447373
,
ENSP00000446630
,
ENST00000292535
,
ENST00000550008
,
ENST00000546411
,
ENST00000360264
,
ENSP00000451558
,
ENSP00000450125
,
ENSG00000257923
,
ENSP00000353401
,
ENST00000425244
,
ENST00000556210
PRO
P39880
Orphanet
24446
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06400 RB1
394
RB1 C706F [nucleoplasm]
(R-HSA-9659812)
RB1 R661W [nucleoplasm]
(R-HSA-9659801)
RB1 N480del [nucleoplasm]
(R-HSA-9659792)
RB1 C706Y [nucleoplasm]
(R-HSA-9659821)
RB1 R661Q [nucleoplasm]
(R-HSA-9659807)
RB1 I703_E737del [nucleoplasm]
(R-HSA-9661065)
RB1 R830_G887del [cytosol]
(R-HSA-9661059)
RB1 K791* [cytosol]
(R-HSA-9662284)
RB1 Q176* [cytosol]
(R-HSA-9661774)
RB1 S114* [cytosol]
(R-HSA-9661775)
RB1 K765* [cytosol]
(R-HSA-9662281)
RB1 W99* [cytosol]
(R-HSA-9661769)
RB1 S149* [cytosol]
(R-HSA-9661770)
RB1 E166* [cytosol]
(R-HSA-9661767)
RB1 G100* [cytosol]
(R-HSA-9661763)
RB1 E125* [cytosol]
(R-HSA-9661784)
RB1 Q121* [cytosol]
(R-HSA-9661780)
RB1 E184* [cytosol]
(R-HSA-9661781)
RB1 E137* [cytosol]
(R-HSA-9661782)
RB1 K745* [cytosol]
(R-HSA-9662288)
RB1 E209* [cytosol]
(R-HSA-9661776)
RB1 S618* [cytosol]
(R-HSA-9662240)
RB1 S463* [cytosol]
(R-HSA-9662241)
RB1 K720* [cytosol]
(R-HSA-9662269)
RB1 K429* [cytosol]
(R-HSA-9662270)
RB1 K652* [cytosol]
(R-HSA-9662271)
RB1 K715* [cytosol]
(R-HSA-9662264)
RB1 K615* [cytosol]
(R-HSA-9662266)
RB1 K412* [cytosol]
(R-HSA-9662261)
RB1 S567* [cytosol]
(R-HSA-9662218)
RB1 S807* [cytosol]
(R-HSA-9662212)
RB1 R467* [cytosol]
(R-HSA-9662213)
RB1 S834* [cytosol]
(R-HSA-9662210)
RB1 S576* [cytosol]
(R-HSA-9662237)
RB1 S758* [cytosol]
(R-HSA-9662232)
RB1 R7Pfs*24 [cytosol]
(R-HSA-9686292)
RB1 S443* [cytosol]
(R-HSA-9662230)
RB1 S648* [cytosol]
(R-HSA-9662224)
RB1 S391* [cytosol]
(R-HSA-9662225)
RB1 S829* [cytosol]
(R-HSA-9662226)
RB1 D32Tfs*33 [cytosol]
(R-HSA-9688044)
RB1 Y651Ifs*7 [cytosol]
(R-HSA-9688045)
RB1 K143Mfs*19 [cytosol]
(R-HSA-9688046)
RB1 V754Sfs*4 [cytosol]
(R-HSA-9688047)
RB1 L44Rfs*4 [cytosol]
(R-HSA-9688040)
RB1 E97Gfs*13 [cytosol]
(R-HSA-9688041)
RB1 I679* [cytosol]
(R-HSA-9688042)
RB1 W195* [cytosol]
(R-HSA-9689579)
RB1 G100Efs*11 [cytosol]
(R-HSA-9688043)
RB1 S648Tfs*4 [cytosol]
(R-HSA-9688036)
RB1 H281Qfs*6 [cytosol]
(R-HSA-9688037)
RB1 Q384* [cytosol]
(R-HSA-9661925)
RB1 S182Yfs*2 [cytosol]
(R-HSA-9688038)
RB1 L343Sfs*3 [cytosol]
(R-HSA-9688039)
RB1 L337Wfs*12 [cytosol]
(R-HSA-9688032)
RB1 S318* [cytosol]
(R-HSA-9688033)
RB1 N627Mfs*16 [cytosol]
(R-HSA-9688034)
RB1 N290Kfs*20 [cytosol]
(R-HSA-9688035)
RB1 F299Lfs*4 [cytosol]
(R-HSA-9688060)
RB1 Q637* [cytosol]
(R-HSA-9662460)
RB1 L76* [cytosol]
(R-HSA-9688061)
RB1 Q762* [cytosol]
(R-HSA-9662461)
RB1 Y655Lfs*4 [cytosol]
(R-HSA-9688062)
RB1 N480Kfs*13 [cytosol]
(R-HSA-9688063)
RB1 Q444* [cytosol]
(R-HSA-9662463)
RB1 T77Lfs*34 [cytosol]
(R-HSA-9688056)
RB1 E747Gfs*3 [cytosol]
(R-HSA-9688057)
RB1 M825* [cytosol]
(R-HSA-9688058)
RB1 L649Ffs*11 [cytosol]
(R-HSA-9688059)
RB1 N472Ifs*6 [cytosol]
(R-HSA-9688052)
RB1 Y813Kfs*12 [cytosol]
(R-HSA-9688053)
RB1 I324Mfs*17 [cytosol]
(R-HSA-9688054)
RB1 M460Ifs*3 [cytosol]
(R-HSA-9688055)
RB1 Y655Ifs*3 [cytosol]
(R-HSA-9688048)
RB1 L769Cfs*41 [cytosol]
(R-HSA-9688049)
RB1 P28Lfs*37 [cytosol]
(R-HSA-9688050)
RB1 E677Dfs*19 [cytosol]
(R-HSA-9688051)
RB1 P370Lfs*10 [cytosol]
(R-HSA-9688012)
RB1 N593Tfs*11 [cytosol]
(R-HSA-9688013)
RB1 K329* [cytosol]
(R-HSA-9661901)
RB1 S249Ffs*22 [cytosol]
(R-HSA-9688014)
RB1 K240* [cytosol]
(R-HSA-9661902)
RB1 L199Ffs*4 [cytosol]
(R-HSA-9688015)
RB1 P253Gfs*5 [cytosol]
(R-HSA-9688008)
RB1 K289* [cytosol]
(R-HSA-9661896)
RB1 S360Pfs*2 [cytosol]
(R-HSA-9688009)
RB1 E323Kfs*9 [cytosol]
(R-HSA-9688010)
RB1 L326* [cytosol]
(R-HSA-9688011)
RB1 P808Kfs*12 [cytosol]
(R-HSA-9688004)
RB1 D584Nfs*2 [cytosol]
(R-HSA-9688005)
RB1 N406Kfs*4 [cytosol]
(R-HSA-9688006)
RB1 K417Wfs*23 [cytosol]
(R-HSA-9688007)
RB1 L797Ffs*18 [cytosol]
(R-HSA-9688000)
RB1 Q266Hfs*2 [cytosol]
(R-HSA-9688001)
RB1 R255* [cytosol]
(R-HSA-9661889)
RB1 K4* [cytosol]
(R-HSA-9661377)
RB1 P641Afs*12 [cytosol]
(R-HSA-9688002)
RB1 V450Sfs*13 [cytosol]
(R-HSA-9688003)
RB1 K524Rfs*28 [cytosol]
(R-HSA-9688028)
RB1 E280* [cytosol]
(R-HSA-9661916)
RB1 M825Ifs*13 [cytosol]
(R-HSA-9688029)
RB1 M761Nfs*21 [cytosol]
(R-HSA-9688030)
RB1 A11Rfs*20 [cytosol]
(R-HSA-9688031)
RB1 E275* [cytosol]
(R-HSA-9661919)
RB1 A635Gfs*6 [cytosol]
(R-HSA-9688024)
RB1 Q266* [cytosol]
(R-HSA-9661912)
RB1 I66Yfs*11 [cytosol]
(R-HSA-9688025)
RB1 Q257* [cytosol]
(R-HSA-9661913)
RB1 P39Rfs*26 [cytosol]
(R-HSA-9688026)
RB1 T664Nfs*4 [cytosol]
(R-HSA-9688027)
RB1 Y771Lfs*24 [cytosol]
(R-HSA-9688020)
RB1 R320Dfs*12 [cytosol]
(R-HSA-9688021)
RB1 E282* [cytosol]
(R-HSA-9661909)
RB1 L277Pfs*9 [cytosol]
(R-HSA-9688022)
RB1 I124* [cytosol]
(R-HSA-9688023)
RB1 N803Tfs*7 [cytosol]
(R-HSA-9688016)
RB1 M386Ifs*11 [cytosol]
(R-HSA-9688017)
RB1 E72Vfs*34 [cytosol]
(R-HSA-9688018)
RB1 R150Kfs*7 [cytosol]
(R-HSA-9688019)
RB1 L743* [cytosol]
(R-HSA-9687980)
RB1 R7Efs*58 [cytosol]
(R-HSA-9687981)
RB1 T140Nfs*6 [cytosol]
(R-HSA-9687982)
RB1 D479Efs*16 [cytosol]
(R-HSA-9687983)
RB1 L199* [cytosol]
(R-HSA-9661871)
RB1 G801* [cytosol]
(R-HSA-9662377)
RB1 S215* [cytosol]
(R-HSA-9661866)
RB1 G435* [cytosol]
(R-HSA-9662368)
RB1 G581* [cytosol]
(R-HSA-9662369)
RB1 L134* [cytosol]
(R-HSA-9687996)
RB1 Y529Lfs*26 [cytosol]
(R-HSA-9687997)
RB1 S816Qfs*10 [cytosol]
(R-HSA-9687998)
RB1 E693Nfs*3 [cytosol]
(R-HSA-9687999)
RB1 D346Rfs*4 [cytosol]
(R-HSA-9687992)
RB1 Q35* [cytosol]
(R-HSA-9661368)
RB1 I806Lfs*10 [cytosol]
(R-HSA-9687993)
RB1 E54* [cytosol]
(R-HSA-9661369)
RB1 L199Yfs*2 [cytosol]
(R-HSA-9687994)
RB1 E48* [cytosol]
(R-HSA-9661370)
RB1 N854* [cytosol]
(R-HSA-9687995)
RB1 W75* [cytosol]
(R-HSA-9661371)
RB1 L389Ffs*3 [cytosol]
(R-HSA-9687988)
RB1 S230* [cytosol]
(R-HSA-9661876)
RB1 H483Sfs*10 [cytosol]
(R-HSA-9687989)
RB1 S842* [cytosol]
(R-HSA-9687990)
RB1 W78* [cytosol]
(R-HSA-9661366)
RB1 G449Efs*8 [cytosol]
(R-HSA-9687991)
RB1 K63* [cytosol]
(R-HSA-9661367)
RB1 K537Nfs*14 [cytosol]
(R-HSA-9687984)
RB1 L206* [cytosol]
(R-HSA-9661872)
RB1 K63Rfs*38 [cytosol]
(R-HSA-9687985)
RB1 P732Lfs*12 [cytosol]
(R-HSA-9687986)
RB1 L158* [cytosol]
(R-HSA-9661874)
RB1 A562Hfs*49 [cytosol]
(R-HSA-9687987)
RB1 E72* [cytosol]
(R-HSA-9661363)
RB1 G540Afs*3 [cytosol]
(R-HSA-9688172)
RB1 N328Ifs*4 [cytosol]
(R-HSA-9688173)
RB1 E843* [cytosol]
(R-HSA-9662573)
RB1 L385* [cytosol]
(R-HSA-9688174)
RB1 E464* [cytosol]
(R-HSA-9662574)
RB1 N123Tfs*2 [cytosol]
(R-HSA-9688175)
RB1 E112Dfs*6 [cytosol]
(R-HSA-9688168)
RB1 E748* [cytosol]
(R-HSA-9662568)
RB1 M148Ifs*8 [cytosol]
(R-HSA-9688169)
RB1 R661* [cytosol]
(R-HSA-9688170)
RB1 Y453* [cytosol]
(R-HSA-9688164)
RB1 K95* [cytosol]
(R-HSA-9661540)
RB1 M484Vfs*8 [cytosol]
(R-HSA-9688165)
RB1 E533* [cytosol]
(R-HSA-9662565)
RB1 G86* [cytosol]
(R-HSA-9661541)
RB1 V654Sfs*14 [cytosol]
(R-HSA-9688166)
RB1 E747* [cytosol]
(R-HSA-9662566)
RB1 E79* [cytosol]
(R-HSA-9661542)
RB1 C553Wfs*53 [cytosol]
(R-HSA-9688167)
RB1 E677* [cytosol]
(R-HSA-9662567)
RB1 K96* [cytosol]
(R-HSA-9661543)
RB1 C102Yfs*7 [cytosol]
(R-HSA-9688160)
RB1 E737* [cytosol]
(R-HSA-9662560)
RB1 E97* [cytosol]
(R-HSA-9661536)
RB1 R579Qfs*29 [cytosol]
(R-HSA-9688161)
RB1 A525Pfs*7 [cytosol]
(R-HSA-9688162)
RB1 L542Kfs*11 [cytosol]
(R-HSA-9688163)
RB1 F482Sfs*10 [cytosol]
(R-HSA-9688188)
RB1 L797* [cytosol]
(R-HSA-9688189)
RB1 P250Afs*16 [cytosol]
(R-HSA-9688190)
RB1 S194Ffs*7 [cytosol]
(R-HSA-9688191)
RB1 N623Qfs*15 [cytosol]
(R-HSA-9688184)
RB1 T9Rfs*56 [cytosol]
(R-HSA-9688185)
RB1 Y813Qfs*10 [cytosol]
(R-HSA-9688187)
RB1 I768Cfs*23 [cytosol]
(R-HSA-9688180)
RB1 L477Mfs*17 [cytosol]
(R-HSA-9688181)
RB1 E675* [cytosol]
(R-HSA-9662581)
RB1 V654Cfs*4 [cytosol]
(R-HSA-9688182)
RB1 F650Lfs*5 [cytosol]
(R-HSA-9688183)
RB1 P39Sfs*10 [cytosol]
(R-HSA-9688176)
RB1 H281Sfs*2 [cytosol]
(R-HSA-9688177)
RB1 E551* [cytosol]
(R-HSA-9662577)
RB1 C61Vfs*4 [cytosol]
(R-HSA-9688178)
RB1 D145Ifs*8 [cytosol]
(R-HSA-9688179)
RB1 M148Hfs*9 [cytosol]
(R-HSA-9688140)
RB1 E837* [cytosol]
(R-HSA-9662540)
RB1 L158Mfs*19 [cytosol]
(R-HSA-9688141)
RB1 L832Ffs*5 [cytosol]
(R-HSA-9688142)
RB1 E440* [cytosol]
(R-HSA-9662542)
RB1 D224Afs*40 [cytosol]
(R-HSA-9688136)
RB1 P822Qfs*4 [cytosol]
(R-HSA-9688137)
RB1 M148Vfs*8 [cytosol]
(R-HSA-9688138)
RB1 L670Cfs*7 [cytosol]
(R-HSA-9688139)
RB1 E465* [cytosol]
(R-HSA-9662532)
RB1 S414Kfs*14 [cytosol]
(R-HSA-9688133)
RB1 K548Nfs*3 [cytosol]
(R-HSA-9688134)
RB1 L135Tfs*5 [cytosol]
(R-HSA-9688135)
RB1 Q207Tfs*5 [cytosol]
(R-HSA-9688128)
RB1 Q384Tfs*11 [cytosol]
(R-HSA-9688129)
RB1 L797Ffs*14 [cytosol]
(R-HSA-9688130)
RB1 P232Rfs*4 [cytosol]
(R-HSA-9688131)
RB1 T497Hfs*22 [cytosol]
(R-HSA-9688156)
RB1 E817* [cytosol]
(R-HSA-9662556)
RB1 N367* [cytosol]
(R-HSA-9688157)
RB1 L809Rfs*17 [cytosol]
(R-HSA-9688158)
RB1 E693* [cytosol]
(R-HSA-9662558)
RB1 K80* [cytosol]
(R-HSA-9661534)
RB1 W99Lfs*11 [cytosol]
(R-HSA-9688159)
RB1 A15Pfs*3 [cytosol]
(R-HSA-9688152)
RB1 Y239Lfs*25 [cytosol]
(R-HSA-9688153)
RB1 D571Lfs*41 [cytosol]
(R-HSA-9688154)
RB1 N186Ifs*6 [cytosol]
(R-HSA-9688155)
RB1 E837Dfs*12 [cytosol]
(R-HSA-9688148)
RB1 E672* [cytosol]
(R-HSA-9662548)
RB1 H483Yfs*9 [cytosol]
(R-HSA-9688149)
RB1 R775Gfs*35 [cytosol]
(R-HSA-9688150)
RB1 E580* [cytosol]
(R-HSA-9662550)
RB1 G617Rfs*36 [cytosol]
(R-HSA-9688151)
RB1 E492* [cytosol]
(R-HSA-9662551)
RB1 A333Ffs*13 [cytosol]
(R-HSA-9688144)
RB1 L564Sfs*47 [cytosol]
(R-HSA-9688145)
RB1 D156Vfs*19 [cytosol]
(R-HSA-9688147)
RB1 C438Vfs*19 [cytosol]
(R-HSA-9688108)
RB1 C278* [cytosol]
(R-HSA-9688109)
RB1 E209Vfs*3 [cytosol]
(R-HSA-9688110)
RB1 T116Lfs*8 [cytosol]
(R-HSA-9688111)
RB1 R698Afs*22 [cytosol]
(R-HSA-9688104)
RB1 V419* [cytosol]
(R-HSA-9688105)
RB1 I415Nfs*13 [cytosol]
(R-HSA-9688106)
RB1 Y173Ffs*11 [cytosol]
(R-HSA-9688107)
RB1 N133Tfs*3 [cytosol]
(R-HSA-9688100)
RB1 M695Rfs*10 [cytosol]
(R-HSA-9688101)
RB1 R418Sfs*9 [cytosol]
(R-HSA-9688102)
RB1 Q689* [cytosol]
(R-HSA-9662502)
RB1 A74Efs*4 [cytosol]
(R-HSA-9688103)
RB1 W99Yfs*5 [cytosol]
(R-HSA-9688096)
RB1 G442Dfs*15 [cytosol]
(R-HSA-9688097)
RB1 N258Efs*11 [cytosol]
(R-HSA-9688098)
RB1 S182Ifs*3 [cytosol]
(R-HSA-9688099)
RB1 Q436* [cytosol]
(R-HSA-9662499)
RB1 Q395Pfs*11 [cytosol]
(R-HSA-9688124)
RB1 Y606Lfs*47 [cytosol]
(R-HSA-9688125)
RB1 E539* [cytosol]
(R-HSA-9662525)
RB1 L317* [cytosol]
(R-HSA-9688126)
RB1 F104Lfs*7 [cytosol]
(R-HSA-9688127)
RB1 E691* [cytosol]
(R-HSA-9662527)
RB1 D340Yfs*5 [cytosol]
(R-HSA-9688120)
RB1 K740Tfs*10 [cytosol]
(R-HSA-9688121)
RB1 H483Ifs*12 [cytosol]
(R-HSA-9688122)
RB1 R611Lfs*43 [cytosol]
(R-HSA-9688123)
RB1 V291Ifs*9 [cytosol]
(R-HSA-9688116)
RB1 N133* [cytosol]
(R-HSA-9688117)
RB1 R334* [cytosol]
(R-HSA-9688118)
RB1 D697Qfs*23 [cytosol]
(R-HSA-9688119)
RB1 L647Ffs*5 [cytosol]
(R-HSA-9688112)
RB1 I723Nfs*28 [cytosol]
(R-HSA-9688113)
RB1 L486Ifs*6 [cytosol]
(R-HSA-9688114)
RB1 S565* [cytosol]
(R-HSA-9688115)
RB1 Y529Tfs*3 [cytosol]
(R-HSA-9688076)
RB1 Q631* [cytosol]
(R-HSA-9662476)
RB1 S318Nfs*13 [cytosol]
(R-HSA-9688077)
RB1 D856Efs*17 [cytosol]
(R-HSA-9688078)
RB1 P595Lfs*16 [cytosol]
(R-HSA-9688079)
RB1 P777Lfs*33 [cytosol]
(R-HSA-9688072)
RB1 G310Dfs*22 [cytosol]
(R-HSA-9688073)
RB1 P250Sfs*20 [cytosol]
(R-HSA-9688074)
RB1 Q850* [cytosol]
(R-HSA-9662474)
RB1 I124Rfs*6 [cytosol]
(R-HSA-9688075)
RB1 Q702* [cytosol]
(R-HSA-9662475)
RB1 E748Dfs*6 [cytosol]
(R-HSA-9688068)
RB1 Q736* [cytosol]
(R-HSA-9662468)
RB1 R798Qfs*4 [cytosol]
(R-HSA-9688069)
RB1 S588Ffs*6 [cytosol]
(R-HSA-9688070)
RB1 K574* [cytosol]
(R-HSA-9688071)
RB1 D156Mfs*19 [cytosol]
(R-HSA-9688064)
RB1 Y771Cfs*23 [cytosol]
(R-HSA-9688065)
RB1 I66Dfs*44 [cytosol]
(R-HSA-9688066)
RB1 Q685* [cytosol]
(R-HSA-9662466)
RB1 E125Kfs*11 [cytosol]
(R-HSA-9688067)
RB1 Y655Lfs*13 [cytosol]
(R-HSA-9688092)
RB1 R828Kfs*10 [cytosol]
(R-HSA-9688093)
RB1 Y659Ifs*4 [cytosol]
(R-HSA-9688094)
RB1 Q846* [cytosol]
(R-HSA-9662494)
RB1 E97Nfs*14 [cytosol]
(R-HSA-9688095)
RB1 Q770* [cytosol]
(R-HSA-9662495)
RB1 C666* [cytosol]
(R-HSA-9688088)
RB1 Q471* [cytosol]
(R-HSA-9662488)
RB1 R71Efs*39 [cytosol]
(R-HSA-9688089)
RB1 Q504* [cytosol]
(R-HSA-9662489)
RB1 R798Tfs*17 [cytosol]
(R-HSA-9688090)
RB1 Q639* [cytosol]
(R-HSA-9662490)
RB1 N328* [cytosol]
(R-HSA-9688091)
RB1 S576Rfs*34 [cytosol]
(R-HSA-9688084)
RB1 T726Nfs*25 [cytosol]
(R-HSA-9688085)
RB1 Q597* [cytosol]
(R-HSA-9662485)
RB1 I532Nfs*57 [cytosol]
(R-HSA-9688086)
RB1 K577Rfs*34 [cytosol]
(R-HSA-9688087)
RB1 R73Sfs*36 [cytosol]
(R-HSA-9688080)
RB1 E413Kfs*4 [cytosol]
(R-HSA-9688081)
RB1 K844Sfs*5 [cytosol]
(R-HSA-9688082)
RB1 A17Pfs*3 [cytosol]
(R-HSA-9688083)
RB1 Q395* [cytosol]
(R-HSA-9660655)
RB1 L523* [cytosol]
(R-HSA-9662176)
RB1 R251* [cytosol]
(R-HSA-9660640)
RB1 L389* [cytosol]
(R-HSA-9662178)
RB1 Q217* [cytosol]
(R-HSA-9660668)
RB1 Q344* [cytosol]
(R-HSA-9660669)
RB1 S634* [cytosol]
(R-HSA-9662207)
RB1 S565* [cytosol]
(R-HSA-9662200)
RB1 S397* [cytosol]
(R-HSA-9662202)
RB1 S838* [cytosol]
(R-HSA-9662203)
RB1 R556* [cytosol]
(R-HSA-9660661)
RB1 R787* [cytosol]
(R-HSA-9660656)
RB1 G304* [cytosol]
(R-HSA-9662152)
RB1 W516* [cytosol]
(R-HSA-9662660)
RB1 W681* [cytosol]
(R-HSA-9662661)
RB1 E322* [cytosol]
(R-HSA-9662149)
RB1 W563* [cytosol]
(R-HSA-9662656)
RB1 L550* [cytosol]
(R-HSA-9662173)
RB1 R552* [cytosol]
(R-HSA-9660637)
RB1 L512* [cytosol]
(R-HSA-9662168)
RB1 R455* [cytosol]
(R-HSA-9660632)
RB1 R763* [cytosol]
(R-HSA-9662681)
RB1 L779* [cytosol]
(R-HSA-9662169)
RB1 R445* [cytosol]
(R-HSA-9660633)
RB1 R544* [cytosol]
(R-HSA-9662677)
RB1 R320* [cytosol]
(R-HSA-9660630)
RB1 L832* [cytosol]
(R-HSA-9662167)
RB1 Y498* [cytosol]
(R-HSA-9662634)
RB1 Y446* [cytosol]
(R-HSA-9662628)
RB1 Y655* [cytosol]
(R-HSA-9662629)
RB1 E323* [cytosol]
(R-HSA-9662142)
RB1 E364* [cytosol]
(R-HSA-9662143)
RB1 C489* [cytosol]
(R-HSA-9662649)
RB1 G310* [cytosol]
(R-HSA-9662137)
RB1 L335* [cytosol]
(R-HSA-9662139)
RB1 E313* [cytosol]
(R-HSA-9662133)
RB1 E315* [cytosol]
(R-HSA-9662131)
RB1 D479Vfs*14 [cytosol]
(R-HSA-9688204)
RB1 C489Lfs*5 [cytosol]
(R-HSA-9688205)
RB1 Y454* [cytosol]
(R-HSA-9662605)
RB1 E137Rfs*3 [cytosol]
(R-HSA-9688206)
RB1 L676Ffs*16 [cytosol]
(R-HSA-9688207)
RB1 Y728* [cytosol]
(R-HSA-9662607)
RB1 I799Ffs*11 [cytosol]
(R-HSA-9688200)
RB1 D346Vfs*17 [cytosol]
(R-HSA-9688201)
RB1 F514Pfs*8 [cytosol]
(R-HSA-9688202)
RB1 N593Sfs*5 [cytosol]
(R-HSA-9688203)
RB1 T58Yfs*52 [cytosol]
(R-HSA-9688196)
RB1 N522Ifs*2 [cytosol]
(R-HSA-9688197)
RB1 C553Vfs*58 [cytosol]
(R-HSA-9688198)
RB1 P609Cfs*43 [cytosol]
(R-HSA-9688199)
RB1 N269* [cytosol]
(R-HSA-9688192)
RB1 E287Rfs*2 [cytosol]
(R-HSA-9688193)
RB1 E492Lfs*4 [cytosol]
(R-HSA-9688194)
RB1 Q383Nfs*3 [cytosol]
(R-HSA-9688195)
RB1 Y606* [cytosol]
(R-HSA-9662617)
RB1 Y756* [cytosol]
(R-HSA-9662619)
RB1 Y790* [cytosol]
(R-HSA-9662612)
RB1 T502Nfs*17 [cytosol]
(R-HSA-9688208)
RB1 Y709* [cytosol]
(R-HSA-9662608)
RB1 Y749* [cytosol]
(R-HSA-9662611)
RB1 T738_R775del [nucleoplasm]
(R-HSA-9661042)
RB1 [cytosol]
(R-HSA-9660621)
hyperphosphorylated RB1 [nucleoplasm]
(R-HSA-188389)
p-S249-RB1 [nucleoplasm]
(R-HSA-9687343)
p-S230-RB1 [nucleoplasm]
(R-HSA-9687336)
p-T356-RB1 [nucleoplasm]
(R-HSA-9687339)
p-T826-RB1 [nucleoplasm]
(R-HSA-9687334)
p-S252-RB1 [nucleoplasm]
(R-HSA-9687335)
p-S807-RB1 [nucleoplasm]
(R-HSA-9687356)
p-T821-RB1 [nucleoplasm]
(R-HSA-9687357)
p-S795-RB1 [nucleoplasm]
(R-HSA-69226)
p-S612-RB1 [nucleoplasm]
(R-HSA-9687352)
p-S780-RB1 [nucleoplasm]
(R-HSA-9687353)
p-S811-RB1 [nucleoplasm]
(R-HSA-9687354)
RB1 [nucleoplasm]
(R-HSA-68642)
p-S788-RB1 [nucleoplasm]
(R-HSA-9687347)
p-S608-RB1 [nucleoplasm]
(R-HSA-9687351)
p-T373-RB1 [nucleoplasm]
(R-HSA-9687355)
0.611
4
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